CD301b (MGL2) Monoclonal Antibody (11A10-B7), eFluor™ 660, eBioscience | Invitrogen 50-3011-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD301b (MGL2) Monoclonal Antibody (11A10-B7), eFluor™ 660, eBioscience

catalog :

50-3011-82

quantity :

100 µg

price :

US 370

clonality :

monoclonal

host :

rat

conjugate :

efluor 660

clone name :

11A10-B7

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 4

Reference
Kumamoto Y, Linehan M, Weinstein J, Laidlaw B, Craft J, Iwasaki A. CD301b? dermal dendritic cells drive T helper 2 cell-mediated immunity. Immunity. 2013;39:733-43 pubmed publisher
Murakami R, Denda Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T. A unique dermal dendritic cell subset that skews the immune response toward Th2. PLoS ONE. 2013;8:e73270 pubmed publisher
Denda Nagai K, Aida S, Saba K, Suzuki K, Moriyama S, Oo Puthinan S, et al. Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cells. J Biol Chem. 2010;285:19193-204 pubmed publisher
Kumamoto Y, Denda Nagai K, Aida S, Higashi N, Irimura T. MGL2 Dermal dendritic cells are sufficient to initiate contact hypersensitivity in vivo. PLoS ONE. 2009;4:e5619 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD301b (MGL2) Monoclonal Antibody (11A10-B7), eFluor™ 660, eBioscience

Catalog # :

50-3011-82

Quantity :

100 µg

Pricing :

US 370

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test

Species :

Mouse

Clone :

11A10-B7

Isotype :

IgG2a, lambda

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test

Aliases :

CD301; CD301b; macrophage galactose N-acetyl-galactosamine specific lectin 2; macrophage galactose-type C-type lectin 2; Mgl2

more info or order :

Invitrogen product webpage