CD177 Monoclonal Antibody (MEM-166 (MEM166)), eFluor 660, eBioscience | Invitrogen 50-1779-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD177 Monoclonal Antibody (MEM-166 (MEM166)), eFluor 660, eBioscience

catalog :

50-1779-42

quantity :

100 Tests

price :

US 272.00

clonality :

monoclonal

host :

mouse

conjugate :

efluor 660

clone name :

MEM-166 (MEM166)

reactivity :

human

application :

flow cytometry

citations: 3

Reference
Caruccio L, Walkovich K, Bettinotti M, Schuller R, Stroncek D. CD177 polymorphisms: correlation between high-frequency single nucleotide polymorphisms and neutrophil surface protein expression. Transfusion. 2004;44:77-82 pubmed
Kissel K, Scheffler S, Kerowgan M, Bux J. Molecular basis of NB1 (HNA-2a, CD177) deficiency. Blood. 2002;99:4231-3 pubmed
Kissel K, Santoso S, Hofmann C, Stroncek D, Bux J. Molecular basis of the neutrophil glycoprotein NB1 (CD177) involved in the pathogenesis of immune neutropenias and transfusion reactions. Eur J Immunol. 2001;31:1301-9 pubmed

product information

Product Type :

Antibody

Product Name :

CD177 Monoclonal Antibody (MEM-166 (MEM166)), eFluor 660, eBioscience

Catalog # :

50-1779-42

Quantity :

100 Tests

Price :

US 272.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.015 ug)/test

Species :

Human

Clone :

MEM-166 (MEM166)

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.015 ug)/test

Aliases :

1190003K14Rik; CD177; CD177 antigen; CD177 molecule; cell surface receptor; HNA2A; HNA-2a; Human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; Pdp3; Polycythemia rubra vera protein 1; PRV1; PRV-1; RGD1562941; UNQ595/PRO1181