This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD104 (Integrin beta 4) Monoclonal Antibody (439-9B), eFluor 660, eBioscience
catalog :
50-1049-80
quantity :
25 ug
price :
US 177.00
clonality :
monoclonal
host :
rat
conjugate :
efluor 660
clone name :
439-9B

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, flow cytometry
citations: 7
Reference
Brown M, Abdollahi B, Wilkins O, Lu H, Chakraborty P, Ognjenovic N, et al. Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer. Sci Adv. 2022;8:eabj8002 pubmed publisher
Zhu N, Xu X, Wang Y, Zeng M, Yuan Y. EBV latent membrane proteins promote hybrid epithelial-mesenchymal and extreme mesenchymal states of nasopharyngeal carcinoma cells for tumorigenicity. PLoS Pathog. 2021;17:e1009873 pubmed publisher
Menon V, Thomas R, Elgueta C, Horl M, Osborn T, Hallett P, et al. Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells. Stem Cells. 2019;37:1293-1306 pubmed publisher
Bierie B, Pierce S, Kroeger C, Stover D, Pattabiraman D, Thiru P, et al. Integrin-?4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells. Proc Natl Acad Sci U S A. 2017;114:E2337-E2346 pubmed publisher
Wansom D, Light E, Thomas D, Worden F, Prince M, Urba S, et al. Infiltrating lymphocytes and human papillomavirus-16--associated oropharyngeal cancer. Laryngoscope. 2012;122:121-7 pubmed publisher
Simon Assmann P, Leberquier C, Molto N, Uezato T, Bouziges F, Kedinger M. Adhesive properties and integrin expression profiles of two colonic cancer populations differing by their spreading on laminin. J Cell Sci. 1994;107 ( Pt 3):577-87 pubmed
Falcioni R, Sacchi A, Resau J, Kennel S. Monoclonal antibody to human carcinoma-associated protein complex: quantitation in normal and tumor tissue. Cancer Res. 1988;48:816-21 pubmed
product information
Product Type :
Antibody
Product Name :
CD104 (Integrin beta 4) Monoclonal Antibody (439-9B), eFluor 660, eBioscience
Catalog # :
50-1049-80
Quantity :
25 ug
Price :
US 177.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human
Applications :
Flow Cytometry: 1 ug/test, Immunohistochemistry: Assay-Dependent
Species :
Human
Clone :
439-9B
Isotype :
IgG2b
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 ug/test, Immunohistochemistry: Assay-Dependent
Aliases :
AA407042; C230078O20; CD antigen CD104; CD104; CD104 antigen; GP150; integrin beta 4; integrin beta-4; integrin subunit beta 4; integrin, beta 4; Itgb4
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA