This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD70 Monoclonal Antibody (113-16), eFluor 660, eBioscience
catalog :
50-0709-42
quantity :
100 Tests
price :
US 448.00
clonality :
monoclonal
host :
mouse
conjugate :
efluor 660
clone name :
113-16

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 6
Reference
Parakrama R, Fogel E, Chandy C, Augustine T, Coffey M, Tesfa L, et al. Immune characterization of metastatic colorectal cancer patients post reovirus administration. BMC Cancer. 2020;20:569 pubmed publisher
Goel S, Ocean A, Parakrama R, Ghalib M, Chaudhary I, Shah U, et al. Elucidation of Pelareorep Pharmacodynamics in A Phase I Trial in Patients with KRAS-Mutated Colorectal Cancer. Mol Cancer Ther. 2020;19:1148-1156 pubmed publisher
Dong H, Franklin N, Roberts D, Yagita H, Glennie M, Bullock T. CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help. J Immunol. 2012;188:3829-38 pubmed publisher
Shaw J, Wang Y, Ito T, Arima K, Liu Y. Plasmacytoid dendritic cells regulate B-cell growth and differentiation via CD70. Blood. 2010;115:3051-7 pubmed publisher
Yang Z, Novak A, Ziesmer S, Witzig T, Ansell S. Malignant B cells skew the balance of regulatory T cells and TH17 cells in B-cell non-Hodgkin's lymphoma. Cancer Res. 2009;69:5522-30 pubmed publisher
Croft M. The role of TNF superfamily members in T-cell function and diseases. Nat Rev Immunol. 2009;9:271-85 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD70 Monoclonal Antibody (113-16), eFluor 660, eBioscience
Catalog # :
50-0709-42
Quantity :
100 Tests
Price :
US 448.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 uL (0.5 ug)/test
Species :
Human
Clone :
113-16
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.5 ug)/test
Aliases :
CD27 ligand; Cd27l; CD27-L; CD27LG; CD70; CD70 antigen; Cd70 molecule; Ki-24 antigen; surface antigen CD70; Tnfsf7; TNLG8A; tumor necrosis factor (ligand) superfamily, member 7; tumor necrosis factor ligand 8A; tumor necrosis factor ligand superfamily member 7
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA