This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD68 Monoclonal Antibody (FA-11), eFluor 660, eBioscience
catalog :
50-0681-82
quantity :
100 ug
price :
US 415.00
clonality :
monoclonal
host :
rat
conjugate :
efluor 660
clone name :
FA-11

The same clone is also sold as:
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
citations: 15
Reference
Li Q, Du Y, Xiang P, Chen G, Qian X, Li S, et al. Re-Visiting Antioxidant Therapy in Murine Advanced Atherosclerosis with Brussels Chicory, a Typical Vegetable in Mediterranean Diets. Nutrients. 2023;15: pubmed publisher
Pernet E, Sun S, Sarden N, Gona S, Nguyen A, Khan N, et al. Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE. Nature. 2023;614:530-538 pubmed publisher
Tomimatsu M, Matsumoto K, Ashizuka M, Kumagai S, Tanaka S, Nakae T, et al. Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling. Sci Rep. 2022;12:16656 pubmed publisher
Zorzin S, Corsi A, Ciarpella F, Bottani E, Dolci S, Malpeli G, et al. Environmental Enrichment Induces Meningeal Niche Remodeling through TrkB-Mediated Signaling. Int J Mol Sci. 2021;22: pubmed publisher
Golden G, Toledo A, Marki A, Sorrentino J, Morris C, Riley R, et al. Endothelial Heparan Sulfate Mediates Hepatic Neutrophil Trafficking and Injury during Staphylococcus aureus Sepsis. MBio. 2021;12:e0118121 pubmed publisher
He J, Ma M, Li D, Wang K, Wang Q, Li Q, et al. Sulfiredoxin-1 attenuates injury and inflammation in acute pancreatitis through the ROS/ER stress/Cathepsin B axis. Cell Death Dis. 2021;12:626 pubmed publisher
Geng S, Zhang Y, Lee C, Li L. Novel reprogramming of neutrophils modulates inflammation resolution during atherosclerosis. Sci Adv. 2019;5:eaav2309 pubmed publisher
Roy S, Bag A, Dutta S, Polavaram N, Islam R, Schellenburg S, et al. Macrophage-Derived Neuropilin-2 Exhibits Novel Tumor-Promoting Functions. Cancer Res. 2018;78:5600-5617 pubmed publisher
Mucci A, Lopez Rodriguez E, Hetzel M, Liu S, Suzuki T, Happle C, et al. iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice. Stem Cell Reports. 2018;11:696-710 pubmed publisher
Chi B, Wang S, Bi S, Qin W, Wu D, Luo Z, et al. Effects of ganoderic acid A on lipopolysaccharide-induced proinflammatory cytokine release from primary mouse microglia cultures. Exp Ther Med. 2018;15:847-853 pubmed publisher
Masola V, Zaza G, Bellin G, Dall Olmo L, Granata S, Vischini G, et al. Heparanase regulates the M1 polarization of renal macrophages and their crosstalk with renal epithelial tubular cells after ischemia/reperfusion injury. FASEB J. 2018;32:742-756 pubmed publisher
Du J, Paz K, Flynn R, Vulic A, Robinson T, Lineburg K, et al. Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production. Blood. 2017;129:2570-2580 pubmed publisher
Ma S, Sun R, Jiang B, Gao J, Deng W, Liu P, et al. L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration. Mol Cell Biol. 2017;37: pubmed publisher
Stevens S, von Gise A, VanDusen N, Zhou B, Pu W. Epicardium is required for cardiac seeding by yolk sac macrophages, precursors of resident macrophages of the adult heart. Dev Biol. 2016;413:153-159 pubmed publisher
Baruch K, Rosenzweig N, Kertser A, Deczkowska A, Sharif A, Spinrad A, et al. Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology. Nat Commun. 2015;6:7967 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD68 Monoclonal Antibody (FA-11), eFluor 660, eBioscience
Catalog # :
50-0681-82
Quantity :
100 ug
Price :
US 415.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 ug/test, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent
Species :
Mouse
Clone :
FA-11
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 ug/test, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent
Aliases :
CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA