CD25 Monoclonal Antibody (P4A10), eFluor 660, eBioscience™ | Invitrogen 50-0250-41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD25 Monoclonal Antibody (P4A10), eFluor 660, eBioscience™

catalog :

50-0250-41

quantity :

25 Tests

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

efluor 660

clone name :

P4A10

reactivity :

dogs

application :

flow cytometry

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; dogs; 1:20; fig 2	Guzera M, Szulc Dąbrowska L, Cywinska A, Archer J, Winnicka A. In Vitro Influence of Mycophenolic Acid on Selected Parameters of Stimulated Peripheral Canine Lymphocytes. PLoS ONE. 2016;11:e0154429 pubmed publisher
	Gori J, Beard B, Williams N, Ironside C, Swanson D, Scott McIvor R, et al. In vivo protection of activated Tyr22-dihydrofolate reductase gene-modified canine T lymphocytes from methotrexate. J Gene Med. 2013;15:233-41 pubmed publisher
	Bismarck D, Schütze N, Moore P, Büttner M, Alber G, Buttlar H. Canine CD4+CD8+ double positive T cells in peripheral blood have features of activated T cells. Vet Immunol Immunopathol. 2012;149:157-66 pubmed publisher
	Liou L, Walsh K, Vartanian A, Beltran Valero de Bernabe D, Welch M, Campbell K, et al. Functional glycosylation of dystroglycan is crucial for thymocyte development in the mouse. PLoS ONE. 2010;5:e9915 pubmed publisher
	Abrams V, Hwang B, Lesnikova M, Gass M, Wayner E, Castilla Llorente C, et al. A novel monoclonal antibody specific for canine CD25 (P4A10): selection and evaluation of canine Tregs. Vet Immunol Immunopathol. 2010;135:257-65 pubmed publisher
	Mizuno T, Suzuki R, Umeki S, Okuda M. Crossreactivity of antibodies to canine CD25 and Foxp3 and identification of canine CD4+CD25 +Foxp3+ cells in canine peripheral blood. J Vet Med Sci. 2009;71:1561-8 pubmed
	Helfand S, Modiano J, Nowell P. Immunophysiological studies of interleukin-2 and canine lymphocytes. Vet Immunol Immunopathol. 1992;33:1-16 pubmed

product information

Product Type :

Antibody

Product Name :

CD25 Monoclonal Antibody (P4A10), eFluor 660, eBioscience™

Catalog # :

50-0250-41

Quantity :

25 Tests

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Canine

Applications :

Flow Cytometry: 5 µL (0.125 µg)/test

Species :

Canine

Clone :

P4A10

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD25 (IL2 receptor alpha chain/IL2RA) is a cytokine that plays a role in the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2RA) is a heterotrimeric protein complex with a gamma chain also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL2RA, IL2R beta chain (IL2RB), and the IL2R gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric IL2RA chains result in low-affinity receptor, while homodimeric IL2RB chains produce a medium-affinity receptor. The expression of IL2 in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. IL2 is primarily produced by mature T cells. IL2 plays an important role as a growth factor, differentiation factor, and regulator of cell death. IL-2 stimulates the proliferation of B cells, augments natural killer cell activity, and inhibits granulocyte macrophage colony formation. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests a role in the immune response to antigenic stimuli. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.125 µg)/test

Aliases :

ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR