EZH2 Polyclonal Antibody | Invitrogen 49-1043 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EZH2 Polyclonal Antibody

catalog :

49-1043

quantity :

50 ug

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 4

Reference
Diaz Bulnes P, Sáiz M, Corte Iglesias V, Rodrigues Diez R, Bernardo Flórez A, Ruiz Bernet C, et al. Demethylation of H3K9 and H3K27 Contributes to the Tubular Renal Damage Triggered by Endoplasmic Reticulum Stress. Antioxidants (Basel). 2022;11: pubmed publisher
Zhang F, Luo H, Peng W, Wang L, Wang T, Xie Z, et al. Hypoxic condition induced H3K27me3 modification of the LncRNA Tmem235 promoter thus supporting apoptosis of BMSCs. Apoptosis. 2022;27:762-777 pubmed publisher
Hng C, Camp E, Anderson P, Breen J, Zannettino A, Gronthos S. HOPX regulates bone marrow-derived mesenchymal stromal cell fate determination via suppression of adipogenic gene pathways. Sci Rep. 2020;10:11345 pubmed publisher
Shen W, Lai Y, Li L, Liao K, Lai H, Kao S, et al. Methylation and PTEN activation in dental pulp mesenchymal stem cells promotes osteogenesis and reduces oncogenesis. Nat Commun. 2019;10:2226 pubmed publisher

product information

Product Type :

Antibody

Product Name :

EZH2 Polyclonal Antibody

Catalog # :

49-1043

Quantity :

50 ug

Price :

US 451.00

Clonality :

Polyclonal

Purity :

Protein G

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ChIP Assay: 1-10 ug/4x10^6 cells, ChIP-Sequencing: 2 ug/4x10^6 cells, Immunocytochemistry: 1:1,000, Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).

Immunogen :

N-terminus (aa1-343) of the mouse Ezh2 protein

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 1-10 ug/4x10^6 cells, ChIP-Sequencing: 2 ug/4x10^6 cells, Immunocytochemistry: 1:1,000, Western Blot: 1:1,000

Aliases :

an; enhancer of zeste 2 polycomb repressive complex 2 subunit; enhancer of zeste homolog 2; enhancer of zeste homolog 2 (Drosophila); ENX 1; ENX1; Enx-1; Enx1h; EZH 2; EZH1; EZH2; EZH-2; EZH2b; histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; lysine N-methyltransferase 6; mKIAA4065; OTTHUMP00000213774; OTTHUMP00000213778; OTTHUMP00000213779; OTTHUMP00000213780; WVS; WVS2