Phospho-beta Catenin (Ser33, Ser37) Polyclonal Antibody | Invitrogen 48-6000 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-beta Catenin (Ser33, Ser37) Polyclonal Antibody

catalog :

48-6000

quantity :

100µL

price :

US 309.00

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat, common platanna

application :

western blot

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:500; fig 3a	MartÃnez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed publisher
western blot; mouse; 1:300; fig 4	Bautista García P, Reyes J, Martin D, Namorado M, Chavez Munguia B, Soria Castro E, et al. Zona occludens-2 protects against podocyte dysfunction induced by ADR in mice. Am J Physiol Renal Physiol. 2013;304:F77-87 pubmed publisher
	He P, Shen Y. Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. J Neurosci. 2009;29:6545-57 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-beta Catenin (Ser33, Ser37) Polyclonal Antibody

Catalog # :

48-6000

Quantity :

100µL

Price :

US 309.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat, Xenopus laevis

Applications :

Western Blot: 1:1,000

Species :

Human, Mouse, Rat, Xenopus laevis

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.

Immunogen :

Phosphopeptide corresponding to amino acid residues surrounding the phosphoserines 33 and 37 of human -beta -catenin.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

CATNB, CTNB1, CTNNB, catenin, beta