This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
phospho-Tyrosine Monoclonal Antibody (pY20), eFluor 450, eBioscience
catalog :
48-5001-42
quantity :
100 Tests
price :
US 408.00
clonality :
monoclonal
host :
mouse
conjugate :
eFluor 450
clone name :
PY20
application :
flow cytometry
citations: 7
| Reference |
|---|
Oseguera López I, Pérez Cerezales S, Ortiz Sánchez P, Mondragon Payne O, Sanchez Sanchez R, Jiménez Morales I, et al. Perfluorooctane Sulfonate (PFOS) and Perfluorohexane Sulfonate (PFHxS) Alters Protein Phosphorylation, Increase ROS Levels and DNA Fragmentation during In Vitro Capacitation of Boar Spermatozoa. Animals (Basel). 2020;10: pubmed publisher
|
Ruiz Díaz S, Oseguera López I, De La Cuesta Díaz D, García López B, Serres C, Sanchez Calabuig M, et al. The Presence of D-Penicillamine during the In Vitro Capacitation of Stallion Spermatozoa Prolongs Hyperactive-Like Motility and Allows for Sperm Selection by Thermotaxis. Animals (Basel). 2020;10: pubmed publisher
|
Yamakawa N, Tsuchida K, Sugino H. The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors. EMBO J. 2002;21:1684-94 pubmed
|
Lund Johansen F, Davis K, Bishop J, de Waal Malefyt R. Flow cytometric analysis of immunoprecipitates: high-throughput analysis of protein phosphorylation and protein-protein interactions. Cytometry. 2000;39:250-9 pubmed
|
Glenney J, Zokas L, Kamps M. Monoclonal antibodies to phosphotyrosine. J Immunol Methods. 1988;109:277-85 pubmed
|
Takagi S, Daibata M, Last T, Humphreys R, Parker D, Sairenji T. Intracellular localization of tyrosine kinase substrates beneath crosslinked surface immunoglobulins in B cells. J Exp Med. 1991;174:381-8 pubmed
|
product information
Product Type :
Antibody
Product Name :
phospho-Tyrosine Monoclonal Antibody (pY20), eFluor 450, eBioscience
Catalog # :
48-5001-42
Quantity :
100 Tests
Price :
US 408.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Chemical
Applications :
Flow Cytometry: 5 uL (0.06 ug)/test
Species :
Chemical
Clone :
pY20
Isotype :
IgG2b, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
The role of tyrosine phosphorylation in transduction of the mitogenic signal from transmembrane receptors and in transformation by oncogene tyrosine kinases has been the subject of intense investigation for several years. While the phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine -phosphorylated proteins and the biochemical pathways in which they function. The fluorescein (FITC) conjugate of clone PY20 anti-phosphotyrosine is especially useful for the detection of these P-Tyr proteins in immunohistochemical and immunocytochemical protocols in situations wherein the use of a secondary antibody would complicate detection of the protein(s) of interest.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.06 ug)/test
Aliases :
Phosphotyrosine; pTyr; pY
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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