CD150 Monoclonal Antibody (mShad150), eFluor 450, eBioscience™ | Invitrogen 48-1502-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD150 Monoclonal Antibody (mShad150), eFluor 450, eBioscience™

catalog :

48-1502-80

quantity :

25 µg

price :

US 309.00

clonality :

monoclonal

host :

rat

conjugate :

eFluor 450

clone name :

mShad150

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 1h	Kaufmann E, Sanz J, Dunn J, Khan N, Mendonça L, Pacis A, et al. BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis. Cell. 2018;172:176-190.e19 pubmed publisher
	Xia P, Wang S, Ye B, Du Y, Li C, Xiong Z, et al. A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion. Immunity. 2018;48:688-701.e7 pubmed publisher
	Guo X, Chu L, Ke F, Mu L, Li Z, Cai J, et al. Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells. Oncotarget. 2017;8:108981-108988 pubmed publisher
	Zhao Y, Wu K, Nguyen C, Smbatyan G, Melendez E, Higuchi Y, et al. Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation. PLoS ONE. 2017;12:e0177245 pubmed publisher
	Barrett N, Malouf C, Kapeni C, Bacon W, Giotopoulos G, Jacobsen S, et al. Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development. Cell Rep. 2016;16:1039-1054 pubmed publisher
	Ku C, Hosoya T, Maillard I, Engel J. GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry. Blood. 2012;119:2242-51 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD150 Monoclonal Antibody (mShad150), eFluor 450, eBioscience™

Catalog # :

48-1502-80

Quantity :

25 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test

Species :

Mouse

Clone :

mShad150

Isotype :

IgG2b, lambda

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test

Aliases :

4933415F16; AA177906; CD150; CD150 antigen; CDw150; ESTM51; IPO-3; RGD1560634; signaling lymphocyte activation molecule; signaling lymphocytic activation molecule; signaling lymphocytic activation molecule family member 1; Slam; SLAM family member 1; Slamf1

more info or order :

Invitrogen product webpage