Doublecortin Polyclonal Antibody | Invitrogen 48-1200 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Doublecortin Polyclonal Antibody

catalog :

48-1200

quantity :

100 ug

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 11

Reference
Dumrongprechachan V, Salisbury R, Butler L, MacDonald M, Kozorovitskiy Y. Dynamic proteomic and phosphoproteomic atlas of corticostriatal axons in neurodevelopment. elife. 2022;11: pubmed publisher
Trinh V, Roland J, Wong J, Revetta F, Patel K, Shi C, et al. Peak density of immature nerve cells occurs with high-grade dysplasia in intraductal papillary mucinous neoplasms of the pancreas. J Pathol. 2022;258:69-82 pubmed publisher
Li W, Fu X, Wang Z, Li Z, Ma D, Sun P, et al. Krüppel-like factor 7 attenuates hippocampal neuronal injury after traumatic brain injury. Neural Regen Res. 2022;17:661-672 pubmed publisher
Jones N, Watson K, Rebeck G. High-fat diet increases gliosis and immediate early gene expression in APOE3 mice, but not APOE4 mice. J Neuroinflammation. 2021;18:214 pubmed publisher
Pottmeier P, Doszyn O, Peuckert C, Jazin E. Increased Expression of Y-Encoded Demethylases During Differentiation of Human Male Neural Stem Cells. Stem Cells Dev. 2020;29:1497-1509 pubmed publisher
Taylor A, González C, Ferretti P, Jackman R. Spontaneous Differentiation of Human Neural Stem Cells on Nanodiamonds. Adv Biosyst. 2019;3:e1800299 pubmed publisher
Helenes González C, Jayasinghe S, Ferretti P. Bio-electrosprayed human neural stem cells are viable and maintain their differentiation potential. F1000Res. 2020;9:267 pubmed publisher
Yohn C, Shifman S, Garino A, Diethorn E, Bokka L, Ashamalla S, et al. Fluoxetine effects on behavior and adult hippocampal neurogenesis in female C57BL/6J mice across the estrous cycle. Psychopharmacology (Berl). 2020;237:1281-1290 pubmed publisher
Yohn C, Ashamalla S, Bokka L, Gergues M, Garino A, Samuels B. Social instability is an effective chronic stress paradigm for both male and female mice. Neuropharmacology. 2019;160:107780 pubmed publisher
Papadimitriou C, Celikkaya H, Cosacak M, Mashkaryan V, Bray L, Bhattarai P, et al. 3D Culture Method for Alzheimer's Disease Modeling Reveals Interleukin-4 Rescues A?42-Induced Loss of Human Neural Stem Cell Plasticity. Dev Cell. 2018;46:85-101.e8 pubmed publisher
Moslehi M, Ng D, Bogoyevitch M. Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus. Sci Rep. 2017;7:5245 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Doublecortin Polyclonal Antibody

Catalog # :

48-1200

Quantity :

100 ug

Price :

US 451.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 2 ug/mL, Immunoprecipitation: 5 ug, Western Blot: 1-3 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.

Immunogen :

Synthetic peptide derived from the C-terminal region of the human doublecortin protein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 ug/mL, Immunoprecipitation: 5 ug, Western Blot: 1-3 ug/mL

Aliases :

DBCN; Dbct; DC; Dcn; DCX; doublecortex; doublecortin; doublin; lissencephalin-X; lissencephaly, X-linked (doublecortin); LISX; Lis-X; LIS-XD; Neuronal migration protein doublecortin; OTTHUMP00000023860; OTTHUMP00000216316; SCLH; XLIS