This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD94 Monoclonal Antibody (18d3), eFluor 450, eBioscience
catalog :
48-0941-82
quantity :
100 ug
price :
US 174.00
clonality :
monoclonal
host :
rat
conjugate :
eFluor 450
clone name :
18d3

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
citations: 19
Reference
Parikh B, Bern M, Piersma S, Yang L, Beckman D, Poursine Laurent J, et al. Control of Viral Infection by Natural Killer Cell Inhibitory Receptors. Cell Rep. 2020;32:107969 pubmed publisher
Liu Q, Sanai N, Jin W, La Cava A, Van Kaer L, Shi F. Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation. Nat Neurosci. 2016;19:243-52 pubmed publisher
Liu R, Engels B, Schreiber K, Ciszewski C, Schietinger A, Schreiber H, et al. IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner. Proc Natl Acad Sci U S A. 2013;110:8158-63 pubmed publisher
Wortham B, Eppert B, Motz G, Flury J, Orozco Levi M, Hoebe K, et al. NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. J Immunol. 2012;188:4468-75 pubmed publisher
Barao I, Alvarez M, Ames E, Orr M, Stefanski H, Blazar B, et al. Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC. Blood. 2011;117:7032-41 pubmed publisher
Elliott J, Wahle J, Yokoyama W. MHC class I-deficient natural killer cells acquire a licensed phenotype after transfer into an MHC class I-sufficient environment. J Exp Med. 2010;207:2073-9 pubmed publisher
Pegram H, Haynes N, Smyth M, Kershaw M, Darcy P. Characterizing the anti-tumor function of adoptively transferred NK cells in vivo. Cancer Immunol Immunother. 2010;59:1235-46 pubmed publisher
Sadri N, Lu J, Badura M, Schneider R. AUF1 is involved in splenic follicular B cell maintenance. BMC Immunol. 2010;11:1 pubmed publisher
Yu J, Wei M, Mao H, Zhang J, Hughes T, Mitsui T, et al. CD94 defines phenotypically and functionally distinct mouse NK cell subsets. J Immunol. 2009;183:4968-74 pubmed publisher
Itsumi M, Yoshikai Y, Yamada H. IL-15 is critical for the maintenance and innate functions of self-specific CD8(+) T cells. Eur J Immunol. 2009;39:1784-93 pubmed publisher
Lee S, Salek Ardakani S, Mittler R, Croft M. Hypercostimulation through 4-1BB distorts homeostasis of immune cells. J Immunol. 2009;182:6753-62 pubmed publisher
French J, Roark C, Born W, O Brien R. Gammadelta T lymphocyte homeostasis is negatively regulated by beta2-microglobulin. J Immunol. 2009;182:1892-900 pubmed publisher
Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, et al. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytometry A. 2008;73:351-60 pubmed publisher
Jänner N, Hahnke K, Mollenkopf H, Steinhoff U, Kaufmann S, Mittrücker H. Restricted expression of C-type lectin-like natural killer receptors by CD8 T cells in the murine small intestine. Immunology. 2008;125:38-47 pubmed publisher
Ohno S, Sato T, Kohu K, Takeda K, Okumura K, Satake M, et al. Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation. Int Immunol. 2008;20:71-9 pubmed
Robbins S, Tessmer M, Van Kaer L, Brossay L. Direct effects of T-bet and MHC class I expression, but not STAT1, on peripheral NK cell maturation. Eur J Immunol. 2005;35:757-65 pubmed
Vance R, Jamieson A, Raulet D. Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells. J Exp Med. 1999;190:1801-12 pubmed
Vance R, Kraft J, Altman J, Jensen P, Raulet D. Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b). J Exp Med. 1998;188:1841-8 pubmed
Vance R, Tanamachi D, Hanke T, Raulet D. Cloning of a mouse homolog of CD94 extends the family of C-type lectins on murine natural killer cells. Eur J Immunol. 1997;27:3236-41 pubmed
product information
Product Type :
Antibody
Product Name :
CD94 Monoclonal Antibody (18d3), eFluor 450, eBioscience
Catalog # :
48-0941-82
Quantity :
100 ug
Price :
US 174.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.125 ug/test
Species :
Mouse
Clone :
18d3
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Natural killer (NK) cells, like CD94, are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.125 ug/test
Aliases :
Cd94; CD94 antigen; CD94 antigen (located within the rat natural killer gene complex); killer cell lectin like receptor D1; Killer cell lectin-like receptor subfamily D member 1; killer cell lectin-like receptor subfamily D, member 1; killer cell lectin-like receptor, subfamily D, member 1; KLRD1; KP43; natural killer cell receptor; natural killer cells antigen CD94; NK cell receptor
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA