product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD16 Monoclonal Antibody (eBioCB16 (CB16)), eFluor 450, eBioscience™
catalog :
48-0168-42
quantity :
100 Tests
price :
US 309.00
clonality :
monoclonal
host :
mouse
conjugate :
eFluor 450
clone name :
eBioCB16 (CB16)
reactivity :
human
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 39
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:100; loading ...; fig s1a
Cassetta L, Fragkogianni S, Sims A, Swierczak A, Forrester L, Zhang H, et al. Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets. Cancer Cell. 2019;35:588-602.e10 pubmed publisher
  • flow cytometry; human; fig 3
Rönn R, Guibentif C, Moraghebi R, Chaves P, Saxena S, Garcia B, et al. Retinoic acid regulates hematopoietic development from human pluripotent stem cells. Stem Cell Reports. 2015;4:269-81 pubmed publisher
Wu X, Hollingshead N, Roberto J, Knupp A, Kenerson H, Chen A, et al. Human Liver Macrophage Subsets Defined by CD32. Front Immunol. 2020;11:2108 pubmed publisher
Violari A, Cotton M, Kuhn L, Schramm D, Paximadis M, Loubser S, et al. A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation. Nat Commun. 2019;10:412 pubmed publisher
Kan B, Michalski C, Fu H, Au H, Lee K, Marchant E, et al. Cellular metabolism constrains innate immune responses in early human ontogeny. Nat Commun. 2018;9:4822 pubmed publisher
Lebedeva A, Vorobyeva D, Vagida M, Ivanova O, Felker E, Fitzgerald W, et al. Ex vivo culture of human atherosclerotic plaques: A model to study immune cells in atherogenesis. Atherosclerosis. 2017;267:90-98 pubmed publisher
Dabas R, Lee R, Servito M, Dharmani Khan P, Modi M, van Slyke T, et al. Antithymocyte Globulin at Clinically Relevant Concentrations Kills Leukemic Blasts. Biol Blood Marrow Transplant. 2016;22:815-24 pubmed publisher
Wang H, Yu J, Li L. A DNA vaccine encoding mutated HPV58 mE6E7-Fc-GPI fusion antigen and GM-CSF and B7.1. Onco Targets Ther. 2015;8:3067-77 pubmed publisher
Sakthivel P, Grunewald J, Eklund A, Bruder D, Wahlström J. Pulmonary sarcoidosis is associated with high-level inducible co-stimulator (ICOS) expression on lung regulatory T cells--possible implications for the ICOS/ICOS-ligand axis in disease course and resolution. Clin Exp Immunol. 2016;183:294-306 pubmed publisher
Kragstrup T, Jalilian B, Hvid M, Kjærgaard A, Østgård R, Schiøttz Christensen B, et al. Decreased plasma levels of soluble CD18 link leukocyte infiltration with disease activity in spondyloarthritis. Arthritis Res Ther. 2014;16:R42 pubmed publisher
Oshansky C, Gartland A, Wong S, Jeevan T, Wang D, Roddam P, et al. Mucosal immune responses predict clinical outcomes during influenza infection independently of age and viral load. Am J Respir Crit Care Med. 2014;189:449-62 pubmed publisher
Zhang Y, Kwak Kim J, Huang D, Hu L, Liao A. Cyclic changes and relationship between peripheral and endometrial NK cells from women with repeated failure after artificial insemination by donor sperm. Am J Reprod Immunol. 2014;71:44-54 pubmed publisher
He X, Liang H, Hong K, Li H, Peng H, Zhao Y, et al. The potential role of CD16+ V?2V?2 T cell-mediated antibody-dependent cell-mediated cytotoxicity in control of HIV type 1 disease. AIDS Res Hum Retroviruses. 2013;29:1562-70 pubmed publisher
Peruzzi G, Femnou L, Gil Krzewska A, Borrego F, Weck J, Krzewski K, et al. Membrane-type 6 matrix metalloproteinase regulates the activation-induced downmodulation of CD16 in human primary NK cells. J Immunol. 2013;191:1883-94 pubmed publisher
Ohira M, Nishida S, Matsuura T, Muraoka I, Tryphonopoulos P, Fan J, et al. Comparative analysis of T-cell depletion method for clinical immunotherapy-anti-hepatitis c effects of natural killer cells via interferon-? production. Transplant Proc. 2013;45:2045-50 pubmed publisher
Schwarzmaier D, Foell D, Weinhage T, Varga G, Däbritz J. Peripheral monocyte functions and activation in patients with quiescent Crohn's disease. PLoS ONE. 2013;8:e62761 pubmed publisher
Lim S, Kim T, Lee J, Sonn C, Kim K, Kim J, et al. Ex vivo expansion of highly cytotoxic human NK cells by cocultivation with irradiated tumor cells for adoptive immunotherapy. Cancer Res. 2013;73:2598-607 pubmed publisher
Besser M, Shoham T, Harari Steinberg O, Zabari N, Ortenberg R, Yakirevitch A, et al. Development of allogeneic NK cell adoptive transfer therapy in metastatic melanoma patients: in vitro preclinical optimization studies. PLoS ONE. 2013;8:e57922 pubmed publisher
Domaica C, Fuertes M, Uriarte I, Girart M, Sardañons J, Comas D, et al. Human natural killer cell maturation defect supports in vivo CD56(bright) to CD56(dim) lineage development. PLoS ONE. 2012;7:e51677 pubmed publisher
Cloke T, Munder M, Taylor G, Muller I, Kropf P. Characterization of a novel population of low-density granulocytes associated with disease severity in HIV-1 infection. PLoS ONE. 2012;7:e48939 pubmed publisher
Al ofi E, Coffelt S, Anumba D. Monocyte subpopulations from pre-eclamptic patients are abnormally skewed and exhibit exaggerated responses to Toll-like receptor ligands. PLoS ONE. 2012;7:e42217 pubmed publisher
Fiedler R, Neugebauer F, Ulrich C, Wienke A, Gromann C, Storr M, et al. Randomized controlled pilot study of 2 weeks' treatment with high cutoff membrane for hemodialysis patients with elevated C-reactive protein. Artif Organs. 2012;36:886-93 pubmed publisher
Pham B, Piard Ruster K, Silva R, Gallo A, Esquivel C, Martinez O, et al. Changes in natural killer cell subsets in pediatric liver transplant recipients. Pediatr Transplant. 2012;16:176-82 pubmed publisher
Rudnicka K, Włodarczyk M, Moran A, Rechcinski T, Miszczyk E, Matusiak A, et al. Helicobacter pylori antigens as potential modulators of lymphocytes' cytotoxic activity. Microbiol Immunol. 2012;56:62-75 pubmed publisher
Lu Y, Zeng B, Zhang Y, Xiang W, Hu L, Liao A. Quantitative and functional changes in peripheral natural killer cells in women with reproductive failure after artificial insemination with donor sperm. J Reprod Immunol. 2011;91:83-9 pubmed publisher
Landrigan A, Wong M, Utz P. CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism. J Immunol. 2011;187:3033-43 pubmed publisher
Moustaki A, Argyropoulos K, Baxevanis C, Papamichail M, Perez S. Effect of the simultaneous administration of glucocorticoids and IL-15 on human NK cell phenotype, proliferation and function. Cancer Immunol Immunother. 2011;60:1683-95 pubmed publisher
Araya N, Takahashi K, Sato T, Nakamura T, Sawa C, Hasegawa D, et al. Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type-1-associated neurological disease. Antivir Ther. 2011;16:89-98 pubmed publisher
Qin H, Lee I, Panagiotopoulos C, Wang X, Chu A, Utz P, et al. Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling. Diabetes. 2011;60:857-66 pubmed publisher
Banerjee S, Lin C, Skinner K, Schiffhauer L, Peacock J, Hicks D, et al. Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression. Cancer Res. 2011;71:318-27 pubmed publisher
Allan D, Rybalov B, Awong G, Zuniga Pflucker J, Kopcow H, Carlyle J, et al. TGF-? affects development and differentiation of human natural killer cell subsets. Eur J Immunol. 2010;40:2289-95 pubmed publisher
Bankey P, Banerjee S, Zucchiatti A, De M, Sleem R, Lin C, et al. Cytokine induced expression of programmed death ligands in human neutrophils. Immunol Lett. 2010;129:100-7 pubmed publisher
Azakami K, Sato T, Araya N, Utsunomiya A, Kubota R, Suzuki K, et al. Severe loss of invariant NKT cells exhibiting anti-HTLV-1 activity in patients with HTLV-1-associated disorders. Blood. 2009;114:3208-15 pubmed publisher
Wang J, Chiu Y. Systemic hypoxia enhances exercise-mediated bactericidal and subsequent apoptotic responses in human neutrophils. J Appl Physiol (1985). 2009;107:1213-22 pubmed publisher
Wang J, Liu H. Systemic hypoxia enhances bactericidal activities of human polymorphonuclear leuocytes. Clin Sci (Lond). 2009;116:805-17 pubmed publisher
Cupedo T, Crellin N, Papazian N, Rombouts E, Weijer K, Grogan J, et al. Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells. Nat Immunol. 2009;10:66-74 pubmed publisher
Tokuyama H, Hagi T, Mattarollo S, Morley J, Wang Q, So H, et al. V gamma 9 V delta 2 T cell cytotoxicity against tumor cells is enhanced by monoclonal antibody drugs--rituximab and trastuzumab. Int J Cancer. 2008;122:2526-34 pubmed publisher
Deaglio S, Zubiaur M, Gregorini A, Bottarel F, Ausiello C, Dianzani U, et al. Human CD38 and CD16 are functionally dependent and physically associated in natural killer cells. Blood. 2002;99:2490-8 pubmed
Zilber M, Gregory S, Mallone R, Deaglio S, Malavasi F, Charron D, et al. CD38 expressed on human monocytes: a coaccessory molecule in the superantigen-induced proliferation. Proc Natl Acad Sci U S A. 2000;97:2840-5 pubmed
product information
Product Type :
Antibody
Product Name :
CD16 Monoclonal Antibody (eBioCB16 (CB16)), eFluor 450, eBioscience™
Catalog # :
48-0168-42
Quantity :
100 Tests
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 µL (0.25 µg)/test
Species :
Human
Clone :
eBioCB16 (CB16)
Isotype :
IgG1, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit. Besides IgG, FCGR3A can be triggered also by oligomeric IgE. FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype. Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 µL (0.25 µg)/test
Aliases :
4833442P21Rik; CD16; CD16-2; CD16A; CD16a antigen; CD16b; CD32; CD32 receptor 2; CDw32; cytolytic trigger molecule G7; Fc fragment of IgG intermediate affinity IV receptor; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG receptor IIIa; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor III; Fc gamma receptor IIIa; Fc gamma receptor III-A; Fc gamma receptor IIIb; Fc gamma RIIIa; Fc gammaRIV; Fc receptor, IgG, low affinity III; Fc receptor, IgG, low affinity IV; Fc receptor-like 3; Fcg receptor III; FCG2; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD 16); Fc-gamma receptor IIIb (CD16); Fc-gamma RII-b; Fc-gamma RII-c; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; fc-gamma RIIIb; fc-gamma RIII-beta; Fc-gamma-RIIb; Fc-gamma-RIIc; FcgammaRIII; FcgammaRIII a.1; FcgammaRIII a.2; FcgammaRIII a.3; FcgammaRIIIA; FcgammaRIV; FCGR2; FCGR2A; FCGR2B; FCGR2C; FCGR3; Fcgr3a; FCGR3B; Fcgr4; FCGRIII; FcgRIV; FcR-10; FcRII-b; FcRII-c; FcRIII; FCRIIIA; FCRIIIb; Fcrl3; IGFR3; IgG Fc gamma receptor III; igG Fc receptor III; IgG Fc receptor III-1; igG Fc receptor III-2; IMD20; immunoglobulin G Fc receptor III; LOC100911825; Low affinity immunoglobulin gamma Fc region receptor III; low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-B; low affinity immunoglobulin gamma Fc region receptor III-like; Low affinity immunoglobulin gamma Fc region receptor IV; neutrophil-specific antigen NA; RP11-5K23.1; transmembrane receptor FcgammaRIII-X
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA