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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD14 Monoclonal Antibody (61D3), eFluor 450, eBioscience™
catalog :
48-0149-41
quantity :
25 Tests
price :
US 309.00
clonality :
monoclonal
host :
mouse
conjugate :
eFluor 450
clone name :
61D3
reactivity :
human
application :
flow cytometry
more info or order :
citations: 109
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s1b
Hadadi E, Zhang B, Baidžajevas K, Yusof N, Puan K, Ong S, et al. Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability. Sci Rep. 2016;6:39035 pubmed publisher
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Ly J, Lagman M, Saing T, Singh M, Tudela E, Morris D, et al. Liposomal Glutathione Supplementation Restores TH1 Cytokine Response to Mycobacterium tuberculosis Infection in HIV-Infected Individuals. J Interferon Cytokine Res. 2015;35:875-87 pubmed publisher
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Wang Y, Wu H, Yang Z, Chi Y, Meng L, Mao A, et al. Human mesenchymal stem cells possess different biological characteristics but do not change their therapeutic potential when cultured in serum free medium. Stem Cell Res Ther. 2014;5:132 pubmed publisher
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Brescia A, Simonds M, McCahan S, Fawcett P, Rose C. The role of transforming growth factor ? signaling in fibroblast-like synoviocytes from patients with oligoarticular juvenile idiopathic arthritis: dysregulation of transforming growth factor ? signaling, including overexpression of bone morphogeneti. Arthritis Rheumatol. 2014;66:1352-62 pubmed publisher
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Spaan M, Groothuismink Z, Koning L, Roomer R, Janssen H, de Knegt R, et al. Erythropoietin administration suppresses human monocyte function in vitro and during therapy-induced anemia in HCV patients. Antiviral Res. 2013;98:469-75 pubmed publisher
Simhadri V, Mariano J, Gil Krzewska A, Zhou Q, Borrego F. CD300c is an activating receptor expressed on human monocytes. J Innate Immun. 2013;5:389-400 pubmed publisher
de Oliveira A, Amadeu T, de França Gomes A, Menezes V, da Costa Nery J, Pinheiro R, et al. Role of CD8(+) T cells in triggering reversal reaction in HIV/leprosy patients. Immunology. 2013;140:47-60 pubmed publisher
Fossati Jimack L, Ling G, Cortini A, Szajna M, Malik T, McDonald J, et al. Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells. PLoS ONE. 2013;8:e57082 pubmed publisher
Lin C, Kift Morgan A, Moser B, Topley N, Eberl M. Suppression of pro-inflammatory T-cell responses by human mesothelial cells. Nephrol Dial Transplant. 2013;28:1743-50 pubmed publisher
Cai W, Qin A, Guo P, Yan D, Hu F, Yang Q, et al. Clinical significance and functional studies of myeloid-derived suppressor cells in chronic hepatitis C patients. J Clin Immunol. 2013;33:798-808 pubmed publisher
Hostmann A, Kapp K, Beutner M, Ritz J, Loddenkemper C, Ignatius R, et al. Dendritic cells from human mesenteric lymph nodes in inflammatory and non-inflammatory bowel diseases: subsets and function of plasmacytoid dendritic cells. Immunology. 2013;139:100-8 pubmed publisher
Amir O, Spivak I, Lavi I, Rahat M. Changes in the monocytic subsets CD14(dim)CD16(+) and CD14(++)CD16(-) in chronic systolic heart failure patients. Mediators Inflamm. 2012;2012:616384 pubmed publisher
Yakubenko V, Hsi L, Cathcart M, Bhattacharjee A. From macrophage interleukin-13 receptor to foam cell formation: mechanisms for ?M?2 integrin interference. J Biol Chem. 2013;288:2778-88 pubmed publisher
Belmonte L, Beutheu Youmba S, Bertiaux Vandaële N, Antonietti M, Lecleire S, Zalar A, et al. Role of toll like receptors in irritable bowel syndrome: differential mucosal immune activation according to the disease subtype. PLoS ONE. 2012;7:e42777 pubmed publisher
Li W, Katz B, Spinola S. Haemophilus ducreyi-induced interleukin-10 promotes a mixed M1 and M2 activation program in human macrophages. Infect Immun. 2012;80:4426-34 pubmed publisher
Dvorakova D, Racil Z, Borsky M, Robesova B, Jeziskova I, Razga F, et al. Clonal heterogeneity in patients with cytogenetically normal acute myeloid leukemia with NPM1 mutations. Leuk Lymphoma. 2013;54:1056-60 pubmed publisher
Søndergaard J, Brix S. Isolation of IL-12p70-competent human monocyte-derived dendritic cells. J Immunol Methods. 2012;386:112-6 pubmed publisher
Shen C, Jia Y, Tian R, Ding M, Zhang C, Wang J. Translation of Pur-? is targeted by cellular miRNAs to modulate the differentiation-dependent susceptibility of monocytes to HIV-1 infection. FASEB J. 2012;26:4755-64 pubmed publisher
Son H, Kim J, Hahn Y, Seo S. Negative regulation of JAK2 by H3K9 methyltransferase G9a in leukemia. Mol Cell Biol. 2012;32:3681-94 pubmed publisher
Leoratti F, Trevelin S, Cunha F, Rocha B, Costa P, Gravina H, et al. Neutrophil paralysis in Plasmodium vivax malaria. PLoS Negl Trop Dis. 2012;6:e1710 pubmed publisher
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McGovern J, Nguyen D, Notley C, Mauri C, Isenberg D, Ehrenstein M. Th17 cells are restrained by Treg cells via the inhibition of interleukin-6 in patients with rheumatoid arthritis responding to anti-tumor necrosis factor antibody therapy. Arthritis Rheum. 2012;64:3129-38 pubmed publisher
Suarez J, Romero Zerbo Y, Márquez L, Rivera P, Iglesias M, Bermudez Silva F, et al. Ulcerative colitis impairs the acylethanolamide-based anti-inflammatory system reversal by 5-aminosalicylic acid and glucocorticoids. PLoS ONE. 2012;7:e37729 pubmed publisher
Bjerg L, Brosbøl Ravnborg A, Tørring C, Dige A, Bundgaard B, Petersen T, et al. Altered frequency of T regulatory cells is associated with disability status in relapsing-remitting multiple sclerosis patients. J Neuroimmunol. 2012;249:76-82 pubmed publisher
Ambarus C, Noordenbos T, de Hair M, Tak P, Baeten D. Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis. Arthritis Res Ther. 2012;14:R74 pubmed publisher
Nair A, Kanda V, Bush Joseph C, Verma N, Chubinskaya S, Mikecz K, et al. Synovial fluid from patients with early osteoarthritis modulates fibroblast-like synoviocyte responses to toll-like receptor 4 and toll-like receptor 2 ligands via soluble CD14. Arthritis Rheum. 2012;64:2268-77 pubmed publisher
Sekine C, Koyanagi A, Koyama N, Hozumi K, Chiba S, Yagita H. Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes. Arthritis Res Ther. 2012;14:R45 pubmed publisher
Osterholt H, Lundeland B, Sonerud T, Saugstad O, Nakstad B. The impact of hyaluronan on monocyte Toll-like receptor expression in term infant cord blood. Acta Paediatr. 2012;101:706-13 pubmed publisher
Liverani E, Banerjee S, Roberts W, Naseem K, Perretti M. Prednisolone exerts exquisite inhibitory properties on platelet functions. Biochem Pharmacol. 2012;83:1364-73 pubmed publisher
Zhang Y, Morgan M, Chen K, Choksi S, Liu Z. Induction of autophagy is essential for monocyte-macrophage differentiation. Blood. 2012;119:2895-905 pubmed publisher
Santer D, Wiedeman A, Teal T, Ghosh P, Elkon K. Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes. J Immunol. 2012;188:902-15 pubmed publisher
Brindley S, Lanham A, Karrer F, Tucker R, Fontenot A, Mack C. Cytomegalovirus-specific T-cell reactivity in biliary atresia at the time of diagnosis is associated with deficits in regulatory T cells. Hepatology. 2012;55:1130-8 pubmed publisher
Ambarus C, Krausz S, van Eijk M, Hamann J, Radstake T, Reedquist K, et al. Systematic validation of specific phenotypic markers for in vitro polarized human macrophages. J Immunol Methods. 2012;375:196-206 pubmed publisher
Doi H, Iyer T, Carpenter E, Li H, Chang K, Vonderheide R, et al. Dysfunctional B-cell activation in cirrhosis resulting from hepatitis C infection associated with disappearance of CD27-positive B-cell population. Hepatology. 2012;55:709-19 pubmed publisher
Landrigan A, Wong M, Utz P. CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism. J Immunol. 2011;187:3033-43 pubmed publisher
Sen A, Chowdhury I, Mukhopadhyay D, Paine S, Mukherjee A, Mondal L, et al. Increased Toll-like receptor-2 expression on nonclassic CD16+ monocytes from patients with inflammatory stage of Eales' disease. Invest Ophthalmol Vis Sci. 2011;52:6940-8 pubmed publisher
Niehage C, Steenblock C, Pursche T, Bornhauser M, Corbeil D, Hoflack B. The cell surface proteome of human mesenchymal stromal cells. PLoS ONE. 2011;6:e20399 pubmed publisher
Li W, Katz B, Spinola S. Haemophilus ducreyi lipooligosaccharides induce expression of the immunosuppressive enzyme indoleamine 2,3-dioxygenase via type I interferons and tumor necrosis factor alpha in human dendritic cells. Infect Immun. 2011;79:3338-47 pubmed publisher
Peng C, Liu B, de Knegt R, Janssen H, Boonstra A. The response to TLR ligation of human CD16?CD14? monocytes is weakly modulated as a consequence of persistent infection with the hepatitis C virus. Mol Immunol. 2011;48:1505-11 pubmed publisher
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Kina K, Masuda H, Nakayama H, Nagatsuka Y, Nabetani T, Hirabayashi Y, et al. The novel neutrophil differentiation marker phosphatidylglucoside mediates neutrophil apoptosis. J Immunol. 2011;186:5323-32 pubmed publisher
von Scheele I, Larsson K, Dahlen B, Billing B, Skedinger M, Lantz A, et al. Toll-like receptor expression in smokers with and without COPD. Respir Med. 2011;105:1222-30 pubmed publisher
Zhang Y, Li J, Lou J, Zhou Y, Bo L, Zhu J, et al. Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients. Crit Care. 2011;15:R70 pubmed publisher
Kwajah M M S, Mustafa N, Holme A, Pervaiz S, Schwarz H. Biphasic activity of CD137 ligand-stimulated monocytes on T cell apoptosis and proliferation. J Leukoc Biol. 2011;89:707-20 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
CD14 Monoclonal Antibody (61D3), eFluor 450, eBioscience™
Catalog # :
48-0149-41
Quantity :
25 Tests
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 µL (0.5 µg)/test
Species :
Human
Clone :
61D3
Isotype :
IgG1, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 µL (0.5 µg)/test
Aliases :
CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA