This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MHC Class I (H-2Kb) Monoclonal Antibody (AF6-88.5.5.3), APC-eFluor™ 780, eBioscience
catalog :
47-5958-82
quantity :
100 µg
price :
US 435
clonality :
monoclonal
host :
mouse
conjugate :
APC/efluor 780
clone name :
AF6-88.5.5.3

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
citations: 18
Reference
Bryan A, Pingali P, Joslyn M, Li H, Bernas T, Koblinski J, et al. High-Dose Acetaminophen with N-acetylcysteine Rescue Inhibits M2 Polarization of Tumor-Associated Macrophages. Cancers (Basel). 2023;15: pubmed publisher
del Rio M, de Juan C, Roncador G, Caleiras E, xc1 lvarez Esteban R, P xe9 rez Sim xf3 n J, et al. Genetic deletion of HVEM in a leukemia B cell line promotes a preferential increase of PD-1- stem cell-like T cells over PD-1+ T cells curbing tumor progression. Front Immunol. 2023;14:1113858 pubmed publisher
Lee S, Lee H, Lee K, Kim M, Kang S, Lee Y, et al. CD8α+ dendritic cells potentiate antitumor and immune activities against murine ovarian cancers. Sci Rep. 2023;13:98 pubmed publisher
Dada S, Ellis S, Wood C, Nohara L, Dreier C, Garcia N, et al. Specific cannabinoids revive adaptive immunity by reversing immune evasion mechanisms in metastatic tumours. Front Immunol. 2022;13:982082 pubmed publisher
Chen H, Ho Y, Mezzadra R, Adrover J, Smolkin R, Zhu C, et al. Senescence rewires microenvironment sensing to facilitate anti-tumor immunity. Cancer Discov. 2022;: pubmed publisher
Liu W, Zhou N, Liu Y, Zhang W, Li X, Wang Y, et al. Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells. Stem Cell Res Ther. 2021;12:153 pubmed publisher
Liu Y, Cai J, Liu W, Lin Y, Guo L, Liu X, et al. Intravenous injection of the oncolytic virus M1 awakens antitumor T cells and overcomes resistance to checkpoint blockade. Cell Death Dis. 2020;11:1062 pubmed publisher
Stokes J, Hoffman E, Molina M, Kummet N, Simpson R, Zeng Y, et al. Bendamustine with total body irradiation conditioning yields tolerant T-cells while preserving T-cell-dependent graft-versus-leukemia. Oncoimmunology. 2020;9:1758011 pubmed publisher
Hilt Z, Ture S, Mohan A, Arne A, Morrell C. Platelet-derived β2m regulates age related monocyte/macrophage functions. Aging (Albany NY). 2019;11:11955-11974 pubmed publisher
Westrich J, Vermeer D, Silva A, Bonney S, Berger J, Cicchini L, et al. CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8+ T-cell responses by upregulating MHC-I expression. Oncogene. 2019;: pubmed publisher
Bullock B, Kimball A, Poczobutt J, Neuwelt A, Li H, Johnson A, et al. Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti-PD-1 response in NSCLC. Life Sci Alliance. 2019;2: pubmed publisher
Li Y, Zhao C, Liu J, Lu Z, Lu M, Gu J, et al. CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity. Oncol Rep. 2019;41:2679-2688 pubmed publisher
Grotzke J, Kozik P, Morel J, Impens F, Pietrosemoli N, Cresswell P, et al. Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export. Proc Natl Acad Sci U S A. 2017;114:E5910-E5919 pubmed publisher
Alloatti A, Rookhuizen D, Joannas L, Carpier J, Iborra S, Magalhaes J, et al. Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity. J Exp Med. 2017;214:2231-2241 pubmed publisher
Baptista M, Keszei M, Oliveira M, Sunahara K, Andersson J, Dahlberg C, et al. Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells. Nat Commun. 2016;7:12175 pubmed publisher
Yuan D, Xia M, Meng G, Xu C, Song Y, Wei J. Anti-angiogenic efficacy of 5'-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs. Oncotarget. 2015;6:29664-74 pubmed publisher
Tähtinen S, Kaikkonen S, Merisalo Soikkeli M, Grönberg Vähä Koskela S, Kanerva A, Parviainen S, et al. Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors. PLoS ONE. 2015;10:e0131242 pubmed publisher
Ramakrishnan R, Tyurin V, Tuyrin V, Veglia F, Condamine T, Amoscato A, et al. Oxidized lipids block antigen cross-presentation by dendritic cells in cancer. J Immunol. 2014;192:2920-31 pubmed publisher
product information
Product Type :
Antibody
Product Name :
MHC Class I (H-2Kb) Monoclonal Antibody (AF6-88.5.5.3), APC-eFluor™ 780, eBioscience
Catalog # :
47-5958-82
Quantity :
100 µg
Price :
US 435
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 µg/test
Species :
Mouse
Clone :
AF6-88.5.5.3
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
This protein is an MHC class I alloantigen, which is involved in antigen presentation to T cells expressing CD3/TCR and CD8. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test
Aliases :
class I major histocompatibility antigen H-2Kd; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2K; H2-K; H-2K(B); H-2K(d); H-2K(K); H-2K(Q); H2-K1; histocompatibility 2, K1, K region; K-f; MHC class I antigen; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC H2-K transplantation antigen
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA