CD5 Monoclonal Antibody (53-7.3), APC-eFluor 780, eBioscience™ | Invitrogen 47-0051-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD5 Monoclonal Antibody (53-7.3), APC-eFluor 780, eBioscience™

catalog :

47-0051-82

quantity :

100 µg

price :

307 USD

clonality :

monoclonal

host :

rat

conjugate :

APC/efluor 780

clone name :

53-7.3

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 7

Reference
Moretti F, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, et al. Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. elife. 2018;7: pubmed publisher
Ruscher R, Hogquist K. Intravenous Labeling and Analysis of the Content of Thymic Perivascular Spaces. Bio Protoc. 2018;8: pubmed publisher
Niemeyer B, Oko L, Medina E, Oldenburg D, White D, Cool C, et al. Host Tumor Suppressor p18INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis. J Virol. 2018;92: pubmed publisher
Freitas C, Hamblin G, Raymond C, Weber K. Naïve helper T cells with high CD5 expression have increased calcium signaling. PLoS ONE. 2017;12:e0178799 pubmed publisher
Thylur R, Wu X, Gowda N, Punnath K, Neelgund S, Febbraio M, et al. CD36 receptor regulates malaria-induced immune responses primarily at early blood stage infection contributing to parasitemia control and resistance to mortality. J Biol Chem. 2017;292:9394-9408 pubmed publisher
Alrefai H, Muhammad K, Rudolf R, Pham D, Klein Hessling S, Patra A, et al. NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells. Nat Commun. 2016;7:11724 pubmed publisher
Pone E, Lam T, Lou Z, Wang R, Chen Y, Liu D, et al. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. J Immunol. 2015;194:3065-78 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD5 Monoclonal Antibody (53-7.3), APC-eFluor 780, eBioscience™

Catalog # :

47-0051-82

Quantity :

100 µg

Price :

307 USD

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.125 µg/test

Species :

Mouse

Clone :

53-7.3

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 µg/test

Aliases :

CD antigen CD5; CD5; CD5 antigen; CD5 antigen (p56-62); CD5 antigen p56-62; Cd5 molecule; CD5 protein; CD74 antigen, invariant polypeptide of major; fCD5; LEU1; Ly-1; Ly-12; Ly-A; Lymphocyte antigen 1; Lymphocyte antigen CD5; lymphocyte antigen T1/Leu-1; Lyt-1; Pan T cell; T1; T-cell surface glycoprotein CD5; unnamed protein product

more info or order :

Invitrogen product webpage