TIGIT Monoclonal Antibody (MBSA43), PerCP-eFluor™ 710, eBioscience | Invitrogen 46-9500-41 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TIGIT Monoclonal Antibody (MBSA43), PerCP-eFluor™ 710, eBioscience

catalog :

46-9500-41

quantity :

25 Tests

price :

US 192.00

clonality :

monoclonal

host :

mouse

conjugate :

Percp/efluor 710

clone name :

MBSA43

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 1	Fromentin R, Bakeman W, Lawani M, Khoury G, Hartogensis W, DaFonseca S, et al. CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART. PLoS Pathog. 2016;12:e1005761 pubmed publisher
	Mekkaoui L, Tejerizo J, Abreu S, Rubat L, Nikoniuk A, Macmorland W, et al. Efficient clinical-grade γ-retroviral vector purification by high-speed centrifugation for CAR T cell manufacturing. Mol Ther Methods Clin Dev. 2023;28:116-128 pubmed publisher
	Ueda T, Shiina S, Iriguchi S, Terakura S, Kawai Y, Kabai R, et al. Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells. Nat Biomed Eng. 2022;: pubmed publisher
	Zebley C, Brown C, Mi T, Fan Y, Alli S, Boi S, et al. CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia. Cell Rep. 2021;37:110079 pubmed publisher
	Lutter L, Roosenboom B, Brand E, Ter Linde J, Oldenburg B, Van Lochem E, et al. Homeostatic Function and Inflammatory Activation of Ileal CD8+ Tissue-Resident T Cells Is Dependent on Mucosal Location. Cell Mol Gastroenterol Hepatol. 2021;12:1567-1581 pubmed publisher
	Abdelsamed H, Zebley C, Nguyen H, Rutishauser R, Fan Y, Ghoneim H, et al. Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nat Immunol. 2020;21:578-587 pubmed publisher
	Esfahani K, Al Aubodah T, Thebault P, Lapointe R, Hudson M, Johnson N, et al. Targeting the mTOR pathway uncouples the efficacy and toxicity of PD-1 blockade in renal transplantation. Nat Commun. 2019;10:4712 pubmed publisher
	Murray D, McMurray J, Eldershaw S, Pearce H, Davies N, Scarisbrick J, et al. Progression of mycosis fungoides occurs through divergence of tumor immunophenotype by differential expression of HLA-DR. Blood Adv. 2019;3:519-530 pubmed publisher
	Fourcade J, Sun Z, Chauvin J, Ka M, Davar D, Pagliano O, et al. CD226 opposes TIGIT to disrupt Tregs in melanoma. JCI Insight. 2018;3: pubmed publisher
	Catakovic K, Gassner F, Ratswohl C, Zaborsky N, Rebhandl S, Schubert M, et al. TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia. Oncoimmunology. 2017;7:e1371399 pubmed publisher
	Belkina A, Snyder Cappione J. OMIP-037: 16-color panel to measure inhibitory receptor signatures from multiple human immune cell subsets. Cytometry A. 2017;91:175-179 pubmed publisher
	Chew G, Fujita T, Webb G, Burwitz B, Wu H, Reed J, et al. TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection. PLoS Pathog. 2016;12:e1005349 pubmed publisher
	Fuhrman C, Yeh W, Seay H, Saikumar Lakshmi P, Chopra G, Zhang L, et al. Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226. J Immunol. 2015;195:145-55 pubmed publisher
	Rueda C, Wells C, Gisslen T, Jobe A, Kallapur S, Chougnet C. Effect of chorioamnionitis on regulatory T cells in moderate/late preterm neonates. Hum Immunol. 2015;76:65-73 pubmed publisher
	Lozano E, Dominguez Villar M, Kuchroo V, Hafler D. The TIGIT/CD226 axis regulates human T cell function. J Immunol. 2012;188:3869-75 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TIGIT Monoclonal Antibody (MBSA43), PerCP-eFluor™ 710, eBioscience

Catalog # :

46-9500-41

Quantity :

25 Tests

Price :

US 192.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.125 µg)/test

Species :

Human

Clone :

MBSA43

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.125 µg)/test

Aliases :

ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM

more info or order :

Invitrogen product webpage