This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD49a (Integrin alpha 1) Monoclonal Antibody (TS2/7), PerCP-eFluor 710, eBioscience
catalog :
46-9490-42
quantity :
100 Tests
price :
US 351.00
clonality :
monoclonal
host :
mouse
conjugate :
Percp/efluor 710
clone name :
TS2/7

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 6
Reference
Corgnac S, Damei I, Gros G, Caidi A, Terry S, Chouaib S, et al. Cancer stem-like cells evade CD8+CD103+ tumor-resident memory T (TRM) lymphocytes by initiating an epithelial-to-mesenchymal transition program in a human lung tumor model. J Immunother Cancer. 2022;10: pubmed publisher
Kramer B, Knoll R, Bonaguro L, ToVinh M, Raabe J, Astaburuaga García R, et al. Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19. Immunity. 2021;54:2650-2669.e14 pubmed publisher
Becker H, Rullo J, Chen M, Ghazarian M, Bak S, Xiao H, et al. ?1?1 integrin-mediated adhesion inhibits macrophage exit from a peripheral inflammatory lesion. J Immunol. 2013;190:4305-14 pubmed publisher
Goldstein I, Ben Horin S, Koltakov A, Chermoshnuk H, Polevoy V, Berkun Y, et al. alpha1beta1 Integrin+ and regulatory Foxp3+ T cells constitute two functionally distinct human CD4+ T cell subsets oppositely modulated by TNFalpha blockade. J Immunol. 2007;178:201-10 pubmed
Goldstein I, Ben Horin S, Li J, Bank I, Jiang H, Chess L. Expression of the alpha1beta1 integrin, VLA-1, marks a distinct subset of human CD4+ memory T cells. J Clin Invest. 2003;112:1444-54 pubmed
Hemler M, Sanchez Madrid F, Flotte T, Krensky A, Burakoff S, Bhan A, et al. Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines. J Immunol. 1984;132:3011-8 pubmed
product information
Product Type :
Antibody
Product Name :
CD49a (Integrin alpha 1) Monoclonal Antibody (TS2/7), PerCP-eFluor 710, eBioscience
Catalog # :
46-9490-42
Quantity :
100 Tests
Price :
US 351.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 uL (0.125 ug)/test
Species :
Human
Clone :
TS2/7
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.125 ug)/test
Aliases :
CD49 antigen-like family member A; CD49a; E130012M19Rik; integrin alpha 1; integrin alpha-1; integrin subunit alpha 1; integrin, alpha 1; Itga1; Laminin and collagen receptor; very late activation protein 1; Vla1; VLA-1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA