This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NKG2AB6 Monoclonal Antibody (16a11), PerCP-eFluor 710, eBioscience
catalog :
46-5897-82
quantity :
100 ug
price :
US 394.00
clonality :
monoclonal
host :
mouse
conjugate :
Percp/efluor 710
clone name :
16A11

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
citations: 7
Reference
Li S, Bern M, Miao B, Fan C, Xing X, Inoue T, et al. The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function. elife. 2022;11: pubmed publisher
Patil N, Domingues O, Masquelier C, Thérésine M, Schlienger O, Njinju Amin Asaba C, et al. Imprint of Initial Education and Loss of Ly49C/I in Activated Natural Killer Cells of TAP1-KO and C57BL/6 Wildtype Mice. Front Immunol. 2022;13:818015 pubmed publisher
Reyes R, Zhang C, Deng Y, Ji N, Mukherjee N, Padrón A, et al. CD122-targeted interleukin-2 and αPD-L1 treat bladder cancer and melanoma via distinct mechanisms, including CD122-driven natural killer cell maturation. Oncoimmunology. 2021;10:2006529 pubmed publisher
Han Q, Mu Y, Zhao H, Zhao R, Guo Q, Su Y, et al. Fasudil prevents liver fibrosis via activating natural killer cells and suppressing hepatic stellate cells. World J Gastroenterol. 2021;27:3581-3594 pubmed publisher
Narasimhan P, Eggert T, Zhu Y, Marcovecchio P, Meyer M, Wu R, et al. Patrolling Monocytes Control NK Cell Expression of Activating and Stimulatory Receptors to Curtail Lung Metastases. J Immunol. 2020;204:192-198 pubmed publisher
Zhang X, Feng J, Chen S, Yang H, Dong Z. Synergized regulation of NK cell education by NKG2A and specific Ly49 family members. Nat Commun. 2019;10:5010 pubmed publisher
Yang M, Chen S, Du J, He J, Wang Y, Li Z, et al. NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. Nat Commun. 2016;7:12730 pubmed publisher
product information
Product Type :
Antibody
Product Name :
NKG2AB6 Monoclonal Antibody (16a11), PerCP-eFluor 710, eBioscience
Catalog # :
46-5897-82
Quantity :
100 ug
Price :
US 394.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Mouse
Applications :
Flow Cytometry: 1 ug/test
Species :
Mouse
Clone :
16a11
Isotype :
IgG2b, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 ug/test
Aliases :
CD159 antigen-like family member A; CD159A; C-lectin type II protein; Cluster of Differentiation 159a; killer cell lectin like receptor C1; killer cell lectin-like receptor subfamily C, member 1; Klrc1; natural killer cell lectin; natural killer group protein 2; NK cell receptor A; NKG2; NKG2-1/B activating NK receptor; NKG2A; NKG2-A/B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2B; rNKG2A
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA