This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ly-49G2 Monoclonal Antibody (eBio4D11 (4D11)), PerCP-eFluor 710, eBioscience
catalog :
46-5781-82
quantity :
100 ug
price :
US 444.00
clonality :
monoclonal
host :
rat
conjugate :
Percp/efluor 710
clone name :
eBio4D11 (4D11)
reactivity :
mouse
application :
flow cytometry
citations: 23
Reference
Kissiov D, Ethell A, Chen S, Wolf N, Zhang C, Dang S, et al. Binary outcomes of enhancer activity underlie stable random monoallelic expression. elife. 2022;11: pubmed publisher
Sheppard S, Santosa E, Lau C, Violante S, Giovanelli P, Kim H, et al. Lactate dehydrogenase A-dependent aerobic glycolysis promotes natural killer cell anti-viral and anti-tumor function. Cell Rep. 2021;35:109210 pubmed publisher
Wagner J, Wong P, Schappe T, Berrien Elliott M, Cubitt C, Jaeger N, et al. Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity. Cell Rep. 2020;31:107720 pubmed publisher
Zhang X, Feng J, Chen S, Yang H, Dong Z. Synergized regulation of NK cell education by NKG2A and specific Ly49 family members. Nat Commun. 2019;10:5010 pubmed publisher
Xu W, Cherrier D, Chea S, Vosshenrich C, Serafini N, Petit M, et al. An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials. Immunity. 2019;50:1054-1068.e3 pubmed publisher
Yang M, Chen S, Du J, He J, Wang Y, Li Z, et al. NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. Nat Commun. 2016;7:12730 pubmed publisher
Yang E, Singh B, Paustian A, Kambayashi T. Diacylglycerol Kinase ? Is a Target To Enhance NK Cell Function. J Immunol. 2016;197:934-41 pubmed publisher
Pyzik M, Dumaine A, Dumaine A, Charbonneau B, Fodil Cornu N, Jonjic S, et al. Viral MHC class I-like molecule allows evasion of NK cell effector responses in vivo. J Immunol. 2014;193:6061-9 pubmed publisher
Sullivan R, Fogel L, Leong J, Schneider S, Wong R, Romee R, et al. MicroRNA-155 tunes both the threshold and extent of NK cell activation via targeting of multiple signaling pathways. J Immunol. 2013;191:5904-13 pubmed publisher
McFall E, Tu M, Al Khattabi N, Tai L, St Laurent A, Tzankova V, et al. Optimized tetramer analysis reveals Ly49 promiscuity for MHC ligands. J Immunol. 2013;191:5722-9 pubmed publisher
Pyzik M, Charbonneau B, Gendron Pontbriand E, Babic M, Krmpotic A, Jonjic S, et al. Distinct MHC class I-dependent NK cell-activating receptors control cytomegalovirus infection in different mouse strains. J Exp Med. 2011;208:1105-17 pubmed publisher
Stadnisky M, Xie X, Coats E, BULLOCK T, Brown M. Self MHC class I-licensed NK cells enhance adaptive CD8 T-cell viral immunity. Blood. 2011;117:5133-41 pubmed publisher
Luther C, Warner K, Takei F. Unique progenitors in mouse lymph node develop into CD127+ NK cells: thymus-dependent and thymus-independent pathways. Blood. 2011;117:4012-21 pubmed publisher
Jonsson A, Yang L, Kim S, Taffner S, Yokoyama W. Effects of MHC class I alleles on licensing of Ly49A+ NK cells. J Immunol. 2010;184:3424-32 pubmed publisher
Hirohashi T, Uehara S, Chase C, Dellapelle P, Madsen J, Russell P, et al. Complement independent antibody-mediated endarteritis and transplant arteriopathy in mice. Am J Transplant. 2010;10:510-7 pubmed publisher
Fodil Cornu N, Pyzik M, Vidal S. Use of inbred mouse strains to map recognition receptors of MCMV infected cells in the NK cell gene locus. Methods Mol Biol. 2010;612:393-409 pubmed publisher
Castillo E, Stonier S, Frasca L, Schluns K. Dendritic cells support the in vivo development and maintenance of NK cells via IL-15 trans-presentation. J Immunol. 2009;183:4948-56 pubmed publisher
Ohno S, Sato T, Kohu K, Takeda K, Okumura K, Satake M, et al. Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation. Int Immunol. 2008;20:71-9 pubmed
Kitchens W, Chase C, Uehara S, Cornell L, Colvin R, Russell P, et al. Macrophage depletion suppresses cardiac allograft vasculopathy in mice. Am J Transplant. 2007;7:2675-82 pubmed
Malarkannan S, Regunathan J, Chu H, Kutlesa S, Chen Y, Zeng H, et al. Bcl10 plays a divergent role in NK cell-mediated cytotoxicity and cytokine generation. J Immunol. 2007;179:3752-62 pubmed
Boos M, Yokota Y, Eberl G, Kee B. Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity. J Exp Med. 2007;204:1119-30 pubmed
Robbins S, Tessmer M, Van Kaer L, Brossay L. Direct effects of T-bet and MHC class I expression, but not STAT1, on peripheral NK cell maturation. Eur J Immunol. 2005;35:757-65 pubmed
Regunathan J, Chen Y, Wang D, Malarkannan S. NKG2D receptor-mediated NK cell function is regulated by inhibitory Ly49 receptors. Blood. 2005;105:233-40 pubmed
product information
Product Type :
Antibody
Product Name :
Ly-49G2 Monoclonal Antibody (eBio4D11 (4D11)), PerCP-eFluor 710, eBioscience
Catalog # :
46-5781-82
Quantity :
100 ug
Price :
US 444.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.125 ug/test
Species :
Mouse
Clone :
eBio4D11 (4D11)
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.125 ug/test
Aliases :
Killer cell lectin-like receptor 7; killer cell lectin-like receptor, subfamily A, member 7; Klra7; LGL-1; Ly49g; ly-49g; Ly49-g; Ly-49G.1; Ly-49G.2; Ly-49G.3; Ly49G.4; Ly49g1; Ly49g2; Ly49g4; Lymphocyte antigen 49g; T-cell surface glycoprotein Ly-49G
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA