product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TCR gamma/delta Monoclonal Antibody (eBioGL3 (GL-3, GL3)), PerCP-eFluor 710, eBioscience™
catalog :
46-5711-82
quantity :
100 µg
price :
US 309.00
clonality :
monoclonal
host :
hamsters
conjugate :
Percp/efluor 710
clone name :
eBioGL3 (GL-3, GL3)
reactivity :
mouse
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 29
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s5f
Ponzetta A, Carriero R, Carnevale S, Barbagallo M, Molgora M, Perucchini C, et al. Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors. Cell. 2019;178:346-360.e24 pubmed publisher
Gal Oz S, Maier B, Yoshida H, Seddu K, Elbaz N, Czysz C, et al. ImmGen report: sexual dimorphism in the immune system transcriptome. Nat Commun. 2019;10:4295 pubmed publisher
Pokrovskii M, Hall J, Ochayon D, Yi R, Chaimowitz N, Seelamneni H, et al. Characterization of Transcriptional Regulatory Networks that Promote and Restrict Identities and Functions of Intestinal Innate Lymphoid Cells. Immunity. 2019;51:185-197.e6 pubmed publisher
Govindarajan S, Gaublomme D, Van der Cruyssen R, Verheugen E, Van Gassen S, Saeys Y, et al. Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha. Nat Commun. 2018;9:5340 pubmed publisher
Hong M, Gu B, Madison M, Landers C, Tung H, Kim M, et al. Protective role of γδ T cells in cigarette smoke and influenza infection. Mucosal Immunol. 2018;11:894-908 pubmed publisher
Cossarizza A, Chang H, Radbruch A, Akdis M, Andrä I, Annunziato F, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies. Eur J Immunol. 2017;47:1584-1797 pubmed publisher
Hoytema van Konijnenburg D, Reis B, Pedicord V, Farache J, Victora G, Mucida D. Intestinal Epithelial and Intraepithelial T Cell Crosstalk Mediates a Dynamic Response to Infection. Cell. 2017;171:783-794.e13 pubmed publisher
Pedicord V, Lockhart A, Rangan K, Craig J, Loschko J, Rogoz A, et al. Exploiting a host-commensal interaction to promote intestinal barrier function and enteric pathogen tolerance. Sci Immunol. 2016;1: pubmed publisher
Drennan M, Govindarajan S, Verheugen E, Coquet J, Staal J, McGuire C, et al. NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20. J Exp Med. 2016;213:1973-81 pubmed publisher
Akitsu A, Ishigame H, Kakuta S, Chung S, Ikeda S, Shimizu K, et al. IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2(+)Vγ6(+)γδ T cells. Nat Commun. 2015;6:7464 pubmed publisher
Sell S, Dietz M, Schneider A, Holtappels R, Mach M, Winkler T. Control of murine cytomegalovirus infection by γδ T cells. PLoS Pathog. 2015;11:e1004481 pubmed publisher
Nakamura M, Shibata K, Hatano S, Sato T, Ohkawa Y, Yamada H, et al. A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice. J Immunol. 2015;194:243-51 pubmed publisher
Shibata K, Yamada H, Nakamura M, Hatano S, Katsuragi Y, Kominami R, et al. IFN-?-producing and IL-17-producing ?? T cells differentiate at distinct developmental stages in murine fetal thymus. J Immunol. 2014;192:2210-8 pubmed publisher
Yamamoto H, Nakamura Y, Sato K, Takahashi Y, Nomura T, Miyasaka T, et al. Defect of CARD9 leads to impaired accumulation of gamma interferon-producing memory phenotype T cells in lungs and increased susceptibility to pulmonary infection with Cryptococcus neoformans. Infect Immun. 2014;82:1606-15 pubmed publisher
Grishkan I, Ntranos A, Calabresi P, Gocke A. Helper T cells down-regulate CD4 expression upon chronic stimulation giving rise to double-negative T cells. Cell Immunol. 2013;284:68-74 pubmed publisher
Guo Y, Sun X, Shibata K, Yamada H, Muta H, Podack E, et al. CD30 is required for activation of a unique subset of interleukin-17A-producing ?? T cells in innate immunity against Mycobacterium bovis Bacillus Calmette-Guerin infection. Infect Immun. 2013;81:3923-34 pubmed publisher
Kole A, He J, Rivollier A, Silveira D, Kitamura K, Maloy K, et al. Type I IFNs regulate effector and regulatory T cell accumulation and anti-inflammatory cytokine production during T cell-mediated colitis. J Immunol. 2013;191:2771-9 pubmed publisher
Gonzalo Gil E, Criado G, Santiago B, Dotor J, Pablos J, Galindo M. Transforming growth factor (TGF)-? signalling is increased in rheumatoid synovium but TGF-? blockade does not modify experimental arthritis. Clin Exp Immunol. 2013;174:245-55 pubmed publisher
Cheng H, Wu R, Gebre A, Hanna R, Smith D, Parks J, et al. Increased cholesterol content in gammadelta (??) T lymphocytes differentially regulates their activation. PLoS ONE. 2013;8:e63746 pubmed publisher
Mielke L, Jones S, Raverdeau M, Higgs R, Stefanska A, Groom J, et al. Retinoic acid expression associates with enhanced IL-22 production by ?? T cells and innate lymphoid cells and attenuation of intestinal inflammation. J Exp Med. 2013;210:1117-24 pubmed publisher
Oda H, Tamehiro N, Patrick M, Hayakawa K, Suzuki H. Differential requirement for RhoH in development of TCR?? CD8?? IELs and other types of T cells. Immunol Lett. 2013;151:1-9 pubmed publisher
Jiang J, Champion C, Wei B, Liu G, Kelly K. CD8?CXCR5? T cells regulate pathology in the genital tract. Infect Dis Obstet Gynecol. 2013;2013:813238 pubmed publisher
Bahri R, Bollinger A, Bollinger T, Orinska Z, Bulfone Paus S. Ectonucleotidase CD38 demarcates regulatory, memory-like CD8+ T cells with IFN-?-mediated suppressor activities. PLoS ONE. 2012;7:e45234 pubmed publisher
Ribot J, deBarros A, Mancio Silva L, Pamplona A, Silva Santos B. B7-CD28 costimulatory signals control the survival and proliferation of murine and human ?? T cells via IL-2 production. J Immunol. 2012;189:1202-8 pubmed publisher
Hwang J, Kita R, Kwon H, Choi E, Lee S, Udey M, et al. Epidermal ablation of Dlx3 is linked to IL-17-associated skin inflammation. Proc Natl Acad Sci U S A. 2011;108:11566-71 pubmed publisher
Carmi Y, Rinott G, Dotan S, Elkabets M, Rider P, Voronov E, et al. Microenvironment-derived IL-1 and IL-17 interact in the control of lung metastasis. J Immunol. 2011;186:3462-71 pubmed publisher
Gossens K, Naus S, Hollander G, Ziltener H. Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity. PLoS ONE. 2010;5:e12766 pubmed publisher
Redford P, Boonstra A, Read S, Pitt J, Graham C, Stavropoulos E, et al. Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung. Eur J Immunol. 2010;40:2200-10 pubmed publisher
Shang L, Thirunarayanan N, Viejo Borbolla A, Martin A, Bogunovic M, Marchesi F, et al. Expression of the chemokine binding protein M3 promotes marked changes in the accumulation of specific leukocytes subsets within the intestine. Gastroenterology. 2009;137:1006-18, 1018.e1-3 pubmed publisher
product information
Product Type :
Antibody
Product Name :
TCR gamma/delta Monoclonal Antibody (eBioGL3 (GL-3, GL3)), PerCP-eFluor 710, eBioscience™
Catalog # :
46-5711-82
Quantity :
100 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Armenian Hamster
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.125 µg/test
Species :
Mouse
Clone :
eBioGL3 (GL-3, GL3)
Isotype :
IgG
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
TCR gamma/delta (T-cell receptor gamma/delta) are specialized T-cells in the immune system. The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory auto-destructive reactions and are believed to be a method by which the immune system compensates for disease. Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP). However, a small number of T cells lack both CD4 and CD8 (double negative, DN). Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders. Gamma-delta T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than alpha-beta T cells. Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.125 µg/test
Aliases :
RGD1311300; similar to T cell receptor V delta 6; T cell receptor gamma locus; T3/TCR complex; TCR delta gamma; TCR gamma/delta; TCR-CD3 complex; Tcrg; Trg; Trg@
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA