Ki-67 Monoclonal Antibody (20Raj1), PerCP-eFluor 710, eBioscience™ | Invitrogen 46-5699-41 product information

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product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Ki-67 Monoclonal Antibody (20Raj1), PerCP-eFluor 710, eBioscience™

catalog :

46-5699-41

quantity :

25Tests

price :

US 127

clonality :

monoclonal

host :

mouse

conjugate :

Percp/efluor 710

clone name :

20Raj1

reactivity :

human, dogs

application :

flow cytometry

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 9h	Goodier M, Rodríguez Galán A, Lusa C, Nielsen C, Darboe A, Moldoveanu A, et al. Influenza Vaccination Generates Cytokine-Induced Memory-like NK Cells: Impact of Human Cytomegalovirus Infection. J Immunol. 2016;197:313-25 pubmed publisher
flow cytometry; human; fig s3	Tsai C, Liong K, Gunalan M, Li N, Lim D, Fisher D, et al. Type I IFNs and IL-18 regulate the antiviral response of primary human Î³Î´ T cells against dendritic cells infected with Dengue virus. J Immunol. 2015;194:3890-900 pubmed publisher
	Nguyen H, Noguchi S, Sugie K, Matsuo Y, Nguyen C, Koito H, et al. Small-Vessel Vasculopathy Due to Aberrant Autophagy in LAMP-2 Deficiency. Sci Rep. 2018;8:3326 pubmed publisher
	Bikker A, Kruize A, van der Wurff Jacobs K, Peters R, Kleinjan M, Redegeld F, et al. Interleukin-7 and Toll-like receptor 7 induce synergistic B cell and T cell activation. PLoS ONE. 2014;9:e94756 pubmed publisher
	Labuda L, Ateba Ngoa U, Feugap E, Heeringa J, van der Vlugt L, Pires R, et al. Alterations in peripheral blood B cell subsets and dynamics of B cell responses during human schistosomiasis. PLoS Negl Trop Dis. 2013;7:e2094 pubmed publisher
	Jiao Y, Hua W, Zhang T, Zhang Y, Ji Y, Zhang H, et al. Characteristics of CD8+ T cell subsets in Chinese patients with chronic HIV infection during initial ART. AIDS Res Ther. 2011;8:15 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Ki-67 Monoclonal Antibody (20Raj1), PerCP-eFluor 710, eBioscience™

Catalog # :

46-5699-41

Quantity :

25Tests

Price :

US 127

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Canine, Human

Applications :

Flow Cytometry: 5 µL (0.03 µg)/test

Species :

Canine, Human

Clone :

20Raj1

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.03 µg)/test

Aliases :

antigen identified by monoclonal antibody Ki-67; antigen KI-67; KIA; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2