CD87 (UPAR) Monoclonal Antibody (VIM5), PerCP-eFluor 710, eBioscience™ | Invitrogen 46-3879-41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD87 (UPAR) Monoclonal Antibody (VIM5), PerCP-eFluor 710, eBioscience™

catalog :

46-3879-41

quantity :

25Tests

price :

US 196

clonality :

monoclonal

host :

mouse

conjugate :

Percp/efluor 710

clone name :

VIM5

reactivity :

human

application :

flow cytometry

citations: 4

Reference
Ge Y, Elghetany M. Urokinase plasminogen activator receptor (CD87): something old, something new. Lab Hematol. 2003;9:67-71 pubmed
Tarui T, Mazar A, Cines D, Takada Y. Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction. J Biol Chem. 2001;276:3983-90 pubmed
Lanza F, Castoldi G, Castagnari B, Todd R, Moretti S, Spisani S, et al. Expression and functional role of urokinase-type plasminogen activator receptor in normal and acute leukaemic cells. Br J Haematol. 1998;103:110-23 pubmed
Gadd S, Majdic O, Kasinrerk W, Stockinger H, Maurer D, Eher R, et al. M5, a phosphoinositol-linked human myelomonocytic activation-associated antigen. Clin Exp Immunol. 1990;80:252-6 pubmed

product information

Product Type :

Antibody

Product Name :

CD87 (UPAR) Monoclonal Antibody (VIM5), PerCP-eFluor 710, eBioscience™

Catalog # :

46-3879-41

Quantity :

25Tests

Price :

US 196

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.25 µg)/test

Species :

Human

Clone :

VIM5

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Urokinase plasminogen activator receptor (uPAR), also known as CD87, is a glycolipid anchored cell surface protein consisting of three homologous domains. It binds uPA with high affinity and enhances and localizes uPA catalyzed plasminogen activation, and thereby plays a key role in cancer invasion and in several tissue remodelling processes. In addition uPAR also binds to vitronectin and may thereby have biological functions independent of its role in uPA mediated proteolysis. Elevated levels of uPAR are associated with poor prognosis in many types of cancer.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.25 µg)/test

Aliases :

PLAUR, U-PAR, UPAR, URKR, monocyte activation antigen Mo3, u-plasminogen activator receptor form 2, urokinase plasminogen activator surface receptor