Arginase 1 Monoclonal Antibody (A1exF5), PerCP-eFluor 710, eBioscience | Invitrogen 46-3697-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Arginase 1 Monoclonal Antibody (A1exF5), PerCP-eFluor 710, eBioscience

catalog :

46-3697-82

quantity :

100 ug

price :

US 424.00

clonality :

monoclonal

host :

rat

conjugate :

Percp/efluor 710

clone name :

A1exF5

reactivity :

human, mouse

application :

flow cytometry

citations: 24

Reference
Yang J, Xie Y, Xia Z, Ji S, Yang X, Yue D, et al. HucMSC-Exo Induced N2 Polarization of Neutrophils: Implications for Angiogenesis and Tissue Restoration in Wound Healing. Int J Nanomedicine. 2024;19:3555-3575 pubmed publisher
Zimarino C, MOODY W, Davidson S, Munir H, Shields J. Disruption of CD47-SIRPα signaling restores inflammatory function in tumor-associated myeloid-derived suppressor cells. iScience. 2024;27:109546 pubmed publisher
Yang F, Akhtar M, Zhang D, El Mayta R, Shin J, Dorsey J, et al. An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Sci Adv. 2024;10:eadj4678 pubmed publisher
Yang J, Shuai J, Siow L, Lu J, Sun M, An W, et al. MicroRNA-146a-loaded magnesium silicate nanospheres promote bone regeneration in an inflammatory microenvironment. Bone Res. 2024;12:2 pubmed publisher
Liu Y, Zhan Z, Kang Z, Li M, Lv Y, Li S, et al. Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma. Acta Pharm Sin B. 2023;13:4748-4764 pubmed publisher
Bokil A, Le Boulvais B xf8 rkja M, Wolowczyk C, Lamsal A, Prestvik W, Nonstad U, et al. Discovery of a new marker to identify myeloid cells associated with metastatic breast tumours. Cancer Cell Int. 2023;23:279 pubmed publisher
Sheng W, Qin H, Wang T, Zhao J, Fang C, Zhang P, et al. Advanced phosphocreatine-grafted chitosan hydrogel promote wound healing by macrophage modulation. Front Bioeng Biotechnol. 2023;11:1199939 pubmed publisher
Brigo N, Neumaier E, Pfeifhofer Obermair C, Grubwieser P, Engl S, Berger S, et al. Timing of Interleukin-4 Stimulation of Macrophages Determines Their Anti-Microbial Activity during Infection with Salmonella enterica Serovar Typhimurium. Cells. 2023;12: pubmed publisher
Feng L, Luo G, Li Y, Zhang C, Liu Y, Liu Y, et al. Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis. Vet Res. 2023;54:25 pubmed publisher
Li C, Anuraga G, Chang C, Weng T, Hsu H, Ta H, et al. Repurposing nitric oxide donating drugs in cancer therapy through immune modulation. J Exp Clin Cancer Res. 2023;42:22 pubmed publisher
Liao W, Foo H, Tran T, Chai C, Wong W. Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function. Br J Pharmacol. 2023;180:1056-1071 pubmed publisher
Wu H, Liu K, Zhang J. LINC00240/miR-155 axis regulates function of trophoblasts and M2 macrophage polarization via modulating oxidative stress-induced pyroptosis in preeclampsia. Mol Med. 2022;28:119 pubmed publisher
Liu Y, Zhai R, Tong J, Yu Y, Yang L, Gu Y, et al. Angiotensin 1-7 and its analogue decrease blood pressure but aggravate renal damage in preeclamptic mice. Exp Anim. 2022;71:519-528 pubmed publisher
Ding L, Chakrabarti J, Sheriff S, Li Q, Thi Hong H, Sontz R, et al. Toll-like Receptor 9 Pathway Mediates Schlafen+-MDSC Polarization During Helicobacter-induced Gastric Metaplasias. Gastroenterology. 2022;163:411-425.e4 pubmed publisher
Gao T, Huang F, Wang W, Xie Y, Wang B. Interleukin-10 genetically modified clinical-grade mesenchymal stromal cells markedly reinforced functional recovery after spinal cord injury via directing alternative activation of macrophages. Cell Mol Biol Lett. 2022;27:27 pubmed publisher
Dichtl S, Sanin D, Koss C, Willenborg S, Petzold A, Tanzer M, et al. Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF. Life Sci Alliance. 2022;5: pubmed publisher
Trofimova O, Korotkaja K, Skrastina D, Jansons J, Spunde K, Isaguliants M, et al. Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model. Vaccines (Basel). 2021;9: pubmed publisher
Choi J, Kim J, Yi M, Kim M, Yong T. Anisakis pegreffii Extract Induces Airway Inflammation with Airway Remodeling in a Murine Model System. Biomed Res Int. 2021;2021:2522305 pubmed publisher
Dichtl S, Lindenthal L, Zeitler L, Behnke K, Schlösser D, Strobl B, et al. Lactate and IL6 define separable paths of inflammatory metabolic adaptation. Sci Adv. 2021;7: pubmed publisher
Deng J, Tan S, Liu R, Yu W, Chen H, Tang N, et al. Chinese Medicine Formula PSORI-CM02 Alleviates Psoriatic Dermatitis via M-MDSCs and Th17 Crosstalk. Front Pharmacol. 2020;11:563433 pubmed publisher
Hu Q, Peng J, Jiang L, Li W, Su Q, Zhang J, et al. Metformin as a senostatic drug enhances the anticancer efficacy of CDK4/6 inhibitor in head and neck squamous cell carcinoma. Cell Death Dis. 2020;11:925 pubmed publisher
Mirando A, Patil A, Rafie C, Christmas B, Pandey N, Stearns V, et al. Regulation of the tumor immune microenvironment and vascular normalization in TNBC murine models by a novel peptide. Oncoimmunology. 2020;9:1760685 pubmed publisher
Sharma M, Schlegel M, Afonso M, Brown E, RAHMAN K, Weinstock A, et al. Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression. Circ Res. 2020;127:335-353 pubmed publisher
Kang S, Park M, Park S, Choi J, Lee D, Song S, et al. Adoptive transfer of Trichinella spiralis-activated macrophages can ameliorate both Th1- and Th2-activated inflammation in murine models. Sci Rep. 2019;9:6547 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Arginase 1 Monoclonal Antibody (A1exF5), PerCP-eFluor 710, eBioscience

Catalog # :

46-3697-82

Quantity :

100 ug

Price :

US 424.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 0.25 ug/test

Species :

Human, Mouse

Clone :

A1exF5

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Arginase-1 (Arg1) is a 35 kDa enzyme converting L-arginine to urea and L-ornithine, which is the final step in the urea cycle. The resulting polyamines are important for cell proliferation and removal of toxins that arise from protein degradation. By degrading arginine, Arginase 1 deprives NO synthase of its substrate and down-regulates nitric oxide production. In both human and mouse, Arginase 1 is expressed in the liver, neutrophils, myeloid derived suppressor cells (MDSC) and neural stem cells. In human, expression in blood neutrophils but not in CCR3+ granulocytes has been reported. In mice, expression of Arginase 1 is one of the hallmarks of alternatively activated macrophages (M2a). Arginase-1 may be expressed in the myeloid cells infiltrating tumors, and is typically found in the majority of hepatocellular carcinomas. Defects in Arginase 1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia.

Immunogen :

E.coli-derived Recombinant mouse Arginase 1

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test

Aliases :

AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase