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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD335 (NKp46) Monoclonal Antibody (29A1.4), PerCP-eFluor™ 710, eBioscience
catalog :
46-3351-82
quantity :
100 µg
price :
US 401
clonality :
monoclonal
host :
rat
conjugate :
Percp/efluor 710
clone name :
29A1.4
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:100; loading ...
Piersma S, Poursine Laurent J, Yang L, Barber G, Parikh B, Yokoyama W. Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1d
Tizian C, Lahmann A, Hölsken O, Cosovanu C, Kofoed Branzk M, Heinrich F, et al. c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells. elife. 2020;9: pubmed publisher
Sobecki M, Krzywinska E, Nagarajan S, Audig xe9 A, Hu x1ef3 nh K, Zacharjasz J, et al. NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence. Nat Commun. 2021;12:4700 pubmed publisher
Cho S, Rudloff I, Lao J, Pang M, Goldberg R, Bui C, et al. Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities. Nat Commun. 2020;11:5794 pubmed publisher
Zeis P, Lian M, Fan X, Herman J, Hernandez D, Gentek R, et al. In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors. Immunity. 2020;53:775-792.e9 pubmed publisher
Parikh B, Bern M, Piersma S, Yang L, Beckman D, Poursine Laurent J, et al. Control of Viral Infection by Natural Killer Cell Inhibitory Receptors. Cell Rep. 2020;32:107969 pubmed publisher
Zhang X, Feng J, Chen S, Yang H, Dong Z. Synergized regulation of NK cell education by NKG2A and specific Ly49 family members. Nat Commun. 2019;10:5010 pubmed publisher
Sifuentes Dominguez L, Li H, Llano E, Liu Z, Singla A, Patel A, et al. SCGN deficiency results in colitis susceptibility. elife. 2019;8: pubmed publisher
Krzywinska E, Kantari Mimoun C, Kerdiles Y, Sobecki M, Isagawa T, Gotthardt D, et al. Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis. Nat Commun. 2017;8:1597 pubmed publisher
Cuff A, Male V. Conventional NK cells and ILC1 are partially ablated in the livers of Ncr1 iCreTbx21 fl/fl mice. Wellcome Open Res. 2017;2:39 pubmed publisher
Yang M, Chen S, Du J, He J, Wang Y, Li Z, et al. NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. Nat Commun. 2016;7:12730 pubmed publisher
Yang E, Singh B, Paustian A, Kambayashi T. Diacylglycerol Kinase ? Is a Target To Enhance NK Cell Function. J Immunol. 2016;197:934-41 pubmed publisher
Everaere L, Ait Yahia S, Molendi Coste O, Vorng H, Quemener S, LeVu P, et al. Innate lymphoid cells contribute to allergic airway disease exacerbation by obesity. J Allergy Clin Immunol. 2016;138:1309-1318.e11 pubmed publisher
Krneta T, Gillgrass A, Chew M, Ashkar A. The breast tumor microenvironment alters the phenotype and function of natural killer cells. Cell Mol Immunol. 2016;13:628-39 pubmed publisher
Donnelly R, Loftus R, Keating S, Liou K, Biron C, Gardiner C, et al. mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function. J Immunol. 2014;193:4477-84 pubmed publisher
Dengler L, Kühn N, Shin D, Hatesuer B, Schughart K, Wilk E. Cellular changes in blood indicate severe respiratory disease during influenza infections in mice. PLoS ONE. 2014;9:e103149 pubmed publisher
Longman R, Diehl G, Victorio D, Huh J, Galan C, Miraldi E, et al. CX?CR1? mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. J Exp Med. 2014;211:1571-83 pubmed publisher
Menning A, Walter A, Rudolph M, Gashaw I, Fritzemeier K, Roese L. Granulocytes and vascularization regulate uterine bleeding and tissue remodeling in a mouse menstruation model. PLoS ONE. 2012;7:e41800 pubmed publisher
Ota N, Wong K, Valdez P, Zheng Y, Crellin N, Diehl L, et al. IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium. Nat Immunol. 2011;12:941-8 pubmed publisher
Walzer T, Chiossone L, Chaix J, Calver A, Carozzo C, Garrigue Antar L, et al. Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor. Nat Immunol. 2007;8:1337-44 pubmed
Walzer T, Blery M, Chaix J, Fuseri N, Chasson L, Robbins S, et al. Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46. Proc Natl Acad Sci U S A. 2007;104:3384-9 pubmed
product information
Product Type :
Antibody
Product Name :
CD335 (NKp46) Monoclonal Antibody (29A1.4), PerCP-eFluor™ 710, eBioscience
Catalog # :
46-3351-82
Quantity :
100 µg
Pricing :
US 401
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 µg/test
Species :
Mouse
Clone :
29A1.4
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
NKp46 (CD335, NCR1, ) is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. NKp46 consists of two Ig-like domains assembled to leukocyte immunoglobulin-like (LIR) and killer inhibitory receptors (KIR).
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test
Aliases :
1-Mar; activating receptor 1; Ar1; CD335; hNKp46; Kilr1; KILR-1; LY94; Ly-94; lymphocyte antigen 94; Lymphocyte antigen 94 homolog; lymphocyte antigen 94 homolog (activating NK-receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); mAR-1; MAR1 (mouse activating receptor 1); mNKp46; natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; natural killer cell receptor; Ncr1; NK cell-activating receptor; NK receptor KILR-1; NKACTR; Nkp46; NK-p46; NK-p46); rAR-1; rat-activating receptor 1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA