CD196 (CCR6) Monoclonal Antibody (R6H1), PerCP-eFluor 710, eBioscience | Invitrogen 46-1969-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD196 (CCR6) Monoclonal Antibody (R6H1), PerCP-eFluor 710, eBioscience

catalog :

46-1969-42

quantity :

100 Tests

price :

US 459.00

clonality :

monoclonal

host :

mouse

conjugate :

Percp/efluor 710

clone name :

R6H1

reactivity :

human

application :

flow cytometry

citations: 8

Reference
Macdonald K, Dawson N, Huang Q, Dunne J, Levings M, Broady R. Regulatory T cells produce profibrotic cytokines in the skin of patients with systemic sclerosis. J Allergy Clin Immunol. 2015;135:946-.e9 pubmed publisher
Zhang W, Nie L, Wang Y, Wang X, Zhao H, Dongol S, et al. CCL20 Secretion from the Nucleus Pulposus Improves the Recruitment of CCR6-Expressing Th17 Cells to Degenerated IVD Tissues. PLoS ONE. 2013;8:e66286 pubmed publisher
Melis L, Van Praet L, Pircher H, Venken K, Elewaut D. Senescence marker killer cell lectin-like receptor G1 (KLRG1) contributes to TNF-? production by interaction with its soluble E-cadherin ligand in chronically inflamed joints. Ann Rheum Dis. 2014;73:1223-31 pubmed publisher
Tang X, Jo J, Tan A, Sandalova E, Chia A, Tan K, et al. IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells. J Immunol. 2013;190:3142-52 pubmed publisher
Lang J, Kelly M, Freed B, McCarter M, Kedl R, Torres R, et al. Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturation. J Immunol. 2013;190:2090-101 pubmed publisher
Kenna T, Davidson S, Duan R, Bradbury L, McFarlane J, Smith M, et al. Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive ?/? T cells in patients with active ankylosing spondylitis. Arthritis Rheum. 2012;64:1420-9 pubmed publisher
Lugering A, Ross M, Sieker M, Heidemann J, Williams I, Domschke W, et al. CCR6 identifies lymphoid tissue inducer cells within cryptopatches. Clin Exp Immunol. 2010;160:440-9 pubmed publisher
Carramolino L, Kremer L, Goya I, Varona R, Buesa J, Gutierrez J, et al. Down-regulation of the beta-chemokine receptor CCR6 in dendritic cells mediated by TNF-alpha and IL-4. J Leukoc Biol. 1999;66:837-44 pubmed

product information

Product Type :

Antibody

Product Name :

CD196 (CCR6) Monoclonal Antibody (R6H1), PerCP-eFluor 710, eBioscience

Catalog # :

46-1969-42

Quantity :

100 Tests

Price :

US 459.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.125 ug)/test

Species :

Human

Clone :

R6H1

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.125 ug)/test

Aliases :

BN-1; CC chemokine receptor 6; C-C chemokine receptor type 6; C-C CKR-6; C-C motif chemokine receptor 6; CC-CKR-6; CCR6; CCR-6; CD196; chemokine (C-C motif) receptor 6; chemokine (C-C) receptor 6; chemokine receptor-like 3; CKR6; CKRL3; CKR-L3; Cmkbr6; DCR2; DRY6; DRY-6; G protein-coupled receptor 29; GPR29; GPRCY4; GPR-CY4; G-protein coupled receptor 29; KY411; LARC receptor; seven-transmembrane receptor, lymphocyte, 22; STRL22