CD170 (Siglec F) Monoclonal Antibody (1RNM44N), PerCP-eFluor™ 710, eBioscience | Invitrogen 46-1702-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD170 (Siglec F) Monoclonal Antibody (1RNM44N), PerCP-eFluor™ 710, eBioscience

catalog :

46-1702-80

quantity :

25 µg

price :

US 160

clonality :

monoclonal

host :

rat

conjugate :

Percp/efluor 710

clone name :

1RNM44N

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:100; loading ...; fig 6a	Jürgensen H, Nørregaard K, Sibree M, Santoni Rugiu E, Madsen D, Wassilew K, et al. Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins. J Cell Biol. 2019;218:333-349 pubmed publisher
	Lee S, Ishitsuka A, Kuroki T, Lin Y, Shibuya A, Hongu T, et al. Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes. JCI Insight. 2021;6: pubmed publisher
	Liu J, Yang C, Liu T, Deng Z, Fang W, Zhang X, et al. Eosinophils improve cardiac function after myocardial infarction. Nat Commun. 2020;11:6396 pubmed publisher
	Moreau G, Burgess S, Sturek J, Donlan A, Petri W, Mann B. Evaluation of K18-hACE2 Mice as a Model of SARS-CoV-2 Infection. Am J Trop Med Hyg. 2020;103:1215-1219 pubmed publisher
	Toubal A, Kiaf B, Beaudoin L, Cagninacci L, Rhimi M, Fruchet B, et al. Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity. Nat Commun. 2020;11:3755 pubmed publisher
	Casulli J, Fife M, Houston S, Rossi S, Dow J, Williamson E, et al. CD200R deletion promotes a neutrophil niche for Francisella tularensis and increases infectious burden and mortality. Nat Commun. 2019;10:2121 pubmed publisher
	Duong L, Radley Crabb H, Gardner J, Tomay F, Dye D, Grounds M, et al. Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia. Front Genet. 2018;9:526 pubmed publisher
	Hardy R, Fenton C, Croft A, Naylor A, Begum R, Desanti G, et al. 11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis. J Autoimmun. 2018;92:104-113 pubmed publisher
	Wang H, Lin J, Zeng L, Ouyang C, Ran P, Yang P, et al. Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells. Sci Rep. 2017;7:8519 pubmed publisher
	Cohen T, Jones Nelson O, Hotz M, Cheng L, Miller L, Suzich J, et al. S. aureus blocks efferocytosis of neutrophils by macrophages through the activity of its virulence factor alpha toxin. Sci Rep. 2016;6:35466 pubmed publisher
	Hall B, Balan V, Gleiberman A, Strom E, Krasnov P, Virtuoso L, et al. Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells. Aging (Albany NY). 2016;8:1294-315 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD170 (Siglec F) Monoclonal Antibody (1RNM44N), PerCP-eFluor™ 710, eBioscience

Catalog # :

46-1702-80

Quantity :

25 µg

Pricing :

US 160

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.125 µg/test

Species :

Mouse

Clone :

1RNM44N

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 µg/test

Aliases :

CD170; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OBBP2; OB-BP2; Obesity-binding protein 2; sialic acid binding Ig like lectin 5; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin F; sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; sialic acid-binding immunoglobulin-like lectin 5; sialic acid-binding lectin Siglec-F; Siglec; SIGLEC5; siglec-5; Siglecf; Siglec-F

more info or order :

Invitrogen product webpage