CD150 Monoclonal Antibody (mShad150), PerCP-eFluor 710, eBioscience | Invitrogen 46-1502-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD150 Monoclonal Antibody (mShad150), PerCP-eFluor 710, eBioscience

catalog :

46-1502-82

quantity :

100 ug

price :

US 436.00

clonality :

monoclonal

host :

rat

conjugate :

Percp/efluor 710

clone name :

mShad150

reactivity :

mouse

application :

flow cytometry

citations: 12

Reference
Wang Z, Sim H, Liu W, Kim J, Lee J, Kook S, et al. Differential Effects of Endurance Exercise on Musculoskeletal and Hematopoietic Modulation in Old Mice. Aging Dis. 2024;15:755-766 pubmed publisher
Boroumand P, Prescott D, Mukherjee T, Bilan P, Wong M, Shen J, et al. Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity. elife. 2022;11: pubmed publisher
Wu G, Murugesan G, Nagala M, McCraw A, Haslam S, Dell A, et al. Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses. Wellcome Open Res. 2021;6:134 pubmed publisher
Rosu A, El Hachem N, Rapino F, Rouault Pierre K, Jorssen J, Somja J, et al. Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis. J Exp Med. 2021;218: pubmed publisher
Hohsfield L, Najafi A, Ghorbanian Y, Soni N, Hingco E, Kim S, et al. Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNS. J Neuroinflammation. 2020;17:279 pubmed publisher
Shikatani E, Besla R, Ensan S, Upadhye A, Khyzha N, Li A, et al. c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells. Cell Rep. 2019;27:2304-2312.e6 pubmed publisher
Srivastava S, Salter A, Liggitt D, Yechan Gunja S, Sarvothama M, Cooper K, et al. Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting. Cancer Cell. 2019;35:489-503.e8 pubmed publisher
Guo X, Chu L, Ke F, Mu L, Li Z, Cai J, et al. Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells. Oncotarget. 2017;8:108981-108988 pubmed publisher
Zhao Y, Wu K, Nguyen C, Smbatyan G, Melendez E, Higuchi Y, et al. Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation. PLoS ONE. 2017;12:e0177245 pubmed publisher
Luo B, Tseng C, Adams G, Lee A. Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells. Stem Cells Dev. 2013;22:3062-73 pubmed publisher
Capitano M, Nemeth M, Mace T, Salisbury Ruf C, Segal B, McCarthy P, et al. Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner. Blood. 2012;120:2600-9 pubmed
Ku C, Hosoya T, Maillard I, Engel J. GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry. Blood. 2012;119:2242-51 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD150 Monoclonal Antibody (mShad150), PerCP-eFluor 710, eBioscience

Catalog # :

46-1502-82

Quantity :

100 ug

Price :

US 436.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.125 ug/test

Species :

Mouse

Clone :

mShad150

Isotype :

IgG2b, lambda

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 ug/test

Aliases :

4933415F16; AA177906; CD150; CD150 antigen; CDw150; ESTM51; IPO-3; RGD1560634; signaling lymphocyte activation molecule; signaling lymphocytic activation molecule; signaling lymphocytic activation molecule family member 1; Slam; SLAM family member 1; Slamf1