CD81 Monoclonal Antibody (1D6-CD81), PerCP-eFluor 710, eBioscience | Invitrogen 46-0819-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD81 Monoclonal Antibody (1D6-CD81), PerCP-eFluor 710, eBioscience

catalog :

46-0819-42

quantity :

100 Tests

price :

US 422.00

clonality :

monoclonal

host :

mouse

conjugate :

Percp/efluor 710

clone name :

1D6-CD81

reactivity :

human

application :

flow cytometry

citations: 5

Reference
Juul N, Willacy O, Mamand D, Andaloussi S, Eisfeldt J, Chamorro C, et al. Insights into cellular behavior and micromolecular communication in urothelial micrografts. Sci Rep. 2023;13:13589 pubmed publisher
Sunartvanichkul T, Arayapisit T, Sangkhamanee S, Chaweewannakorn C, Iwasaki K, Klaihmon P, et al. Stem cell-derived exosomes from human exfoliated deciduous teeth promote angiogenesis in hyperglycemic-induced human umbilical vein endothelial cells. J Appl Oral Sci. 2023;31:e20220427 pubmed publisher
Porcelli L, Guida M, De Summa S, Di Fonte R, De Risi I, Garofoli M, et al. uPAR+ extracellular vesicles: a robust biomarker of resistance to checkpoint inhibitor immunotherapy in metastatic melanoma patients. J Immunother Cancer. 2021;9: pubmed publisher
Mitchell A, Wanczyk H, JENSEN T, Finck C. Human induced pluripotent stem cells ameliorate hyperoxia-induced lung injury in a mouse model. Am J Transl Res. 2020;12:292-307 pubmed
Giugliano S, Kriss M, Golden Mason L, Dobrinskikh E, Stone A, Soto Gutierrez A, et al. Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication. Gastroenterology. 2015;148:392-402.e13 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD81 Monoclonal Antibody (1D6-CD81), PerCP-eFluor 710, eBioscience

Catalog # :

46-0819-42

Quantity :

100 Tests

Price :

US 422.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.5 ug)/test

Species :

Human

Clone :

1D6-CD81

Isotype :

IgG1

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD81 (TAPA-1, target of anti-proliferative antibody-1) is a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T cells. In muscles, CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. Like members of the tetraspanin family that include CD9, CD37, CD53, CD63, and CD82, CD81 is a cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that is known to complex with integrins. CD81 appears to promote muscle cell fusion and support myotube maintenance. CD81 associates with CD19, CD21, Leu 13, and integrins on cell membrane and acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. CD81 is also localized in the tumor-suppressor gene region and is a candidate gene for malignancies.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.5 ug)/test

Aliases :

26 kDa cell surface protein TAPA-1; CD 81 antigen; Cd81; CD81 antigen; CD81 antigen (target of antiproliferative antibody 1); CD81 molecule; CVID6; S5.7; Tapa1; Tapa-1; Target of the antiproliferative antibody 1; Tetraspanin28; tetraspanin-28; Tspan28; Tspan-28