This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD25 Monoclonal Antibody (OX39), PerCP-eFluor 710, eBioscience
catalog :
46-0390-82
quantity :
100 ug
price :
US 360.00
clonality :
monoclonal
host :
mouse
conjugate :
Percp/efluor 710
clone name :
OX39

The same clone is also sold as:
reactivity :
rat
application :
flow cytometry
citations: 19
Reference
Zhou Y, Zhang Z, Sun Y, Zhou D, Zhao Y, Li J, et al. Liangxue Tongyu Prescription Alleviates Brain Damage in Acute Intracerebral Hemorrhage Rats by Regulating Intestinal Mucosal Barrier Function. Evid Based Complement Alternat Med. 2022;2022:2197763 pubmed publisher
Zou Q, Liu C, Hu N, Wang W, Wang H. miR-126 ameliorates multiple organ dysfunction in septic rats by regulating the differentiation of Th17/Treg. Mol Biol Rep. 2022;49:2985-2998 pubmed publisher
Huang G, Ge Y, Gui Z, Zhu M, Liu J, Wang H. Toxicity of Melastoma dodecandrum Lour. and its effects on lipopolysaccharide-induced inflammation and oxidative stress. Exp Ther Med. 2021;22:807 pubmed publisher
Ge N, Peng J, Yu L, Huang S, Xu L, Su Y, et al. Orthodontic treatment induces Th17/Treg cells to regulate tooth movement in rats with periodontitis. Iran J Basic Med Sci. 2020;23:1315-1322 pubmed publisher
Pai A, West C, de Souza A, Kadam P, Pollner E, West D, et al. Renal T cell infiltration occurs despite attenuation of development of hypertension with hydralazine in Envigo's female Dahl rat maintained on a low-Na+ diet. Am J Physiol Renal Physiol. 2019;317:F572-F583 pubmed publisher
Li Y, Li H, Cao Y, Wu F, Ma W, Wang Y, et al. Placenta‑derived mesenchymal stem cells improve airway hyperresponsiveness and inflammation in asthmatic rats by modulating the Th17/Treg balance. Mol Med Rep. 2017;16:8137-8145 pubmed publisher
Wang G, Zhang Q, Yang Y, Chen W, Liu W, Jiang N, et al. Rapamycin combined with allogenic immature dendritic cells selectively expands CD4+CD25+Foxp3+ regulatory T cells in rats. Hepatobiliary Pancreat Dis Int. 2012;11:203-8 pubmed
Schu S, Nosov M, O Flynn L, Shaw G, Treacy O, Barry F, et al. Immunogenicity of allogeneic mesenchymal stem cells. J Cell Mol Med. 2012;16:2094-103 pubmed publisher
Wang G, Yang Y, Li H, Zhang J, Li M, Zhang Q, et al. Rapamycin combined with donor immature dendritic cells promotes liver allograft survival in association with CD4(+) CD25(+) Foxp3(+) regulatory T cell expansion. Hepatol Res. 2012;42:192-202 pubmed publisher
Tamosiuniene R, Tian W, Dhillon G, Wang L, Sung Y, Gera L, et al. Regulatory T cells limit vascular endothelial injury and prevent pulmonary hypertension. Circ Res. 2011;109:867-79 pubmed publisher
Wu C, Xia Y, Wang P, Lu L, Zhang F. Triptolide protects mice from ischemia/reperfusion injury by inhibition of IL-17 production. Int Immunopharmacol. 2011;11:1564-72 pubmed publisher
Takabatake Y, Li X, Mizui M, Miyasato K, Matsui I, Kawada N, et al. A superagonistic monoclonal antibody for CD28 ameliorates crescentic glomerulonephritis in wistar-kyoto rats. Mol Med. 2011;17:686-96 pubmed publisher
Dominguez M, Lorenzo N, Barbera A, Darrasse Jèze G, Hernández M, Torres A, et al. An altered peptide ligand corresponding to a novel epitope from heat-shock protein 60 induces regulatory T cells and suppresses pathogenic response in an animal model of adjuvant-induced arthritis. Autoimmunity. 2011;44:471-82 pubmed publisher
Visser J, Hillebrands J, Walther Boer M, Bos N, Rozing J. Prevention of diabetes by a hydrolysed casein-based diet in diabetes-prone BioBreeding rats does not involve restoration of the defective natural regulatory T cell function. Diabetologia. 2009;52:1445-7 pubmed publisher
Brugman S, Visser J, Hillebrands J, Bos N, Rozing J. Prolonged exclusive breastfeeding reduces autoimmune diabetes incidence and increases regulatory T-cell frequency in bio-breeding diabetes-prone rats. Diabetes Metab Res Rev. 2009;25:380-7 pubmed publisher
Tischner D, Weishaupt A, van den Brandt J, Müller N, Beyersdorf N, Ip C, et al. Polyclonal expansion of regulatory T cells interferes with effector cell migration in a model of multiple sclerosis. Brain. 2006;129:2635-47 pubmed
Beyersdorf N, Balbach K, Hunig T, Kerkau T. Large-scale expansion of rat CD4+ CD25+ T(reg) cells in the absence of T-cell receptor stimulation. Immunology. 2006;119:441-50 pubmed
Beyersdorf N, Gaupp S, Balbach K, Schmidt J, Toyka K, Lin C, et al. Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis. J Exp Med. 2005;202:445-55 pubmed
Paterson D, Jefferies W, Green J, Brandon M, Corthesy P, Puklavec M, et al. Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Mol Immunol. 1987;24:1281-90 pubmed
product information
Product Type :
Antibody
Product Name :
CD25 Monoclonal Antibody (OX39), PerCP-eFluor 710, eBioscience
Catalog # :
46-0390-82
Quantity :
100 ug
Price :
US 360.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Rat
Applications :
Flow Cytometry: 0.06 ug/test
Species :
Rat
Clone :
OX39
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD25 (IL2 receptor alpha chain/IL2RA) is a cytokine that plays a role in the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2RA) is a heterotrimeric protein complex with a gamma chain also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL2RA, IL2R beta chain (IL2RB), and the IL2R gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric IL2RA chains result in low-affinity receptor, while homodimeric IL2RB chains produce a medium-affinity receptor. The expression of IL2 in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. IL2 is primarily produced by mature T cells. IL2 plays an important role as a growth factor, differentiation factor, and regulator of cell death. IL-2 stimulates the proliferation of B cells, augments natural killer cell activity, and inhibits granulocyte macrophage colony formation. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests a role in the immune response to antigenic stimuli. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.06 ug/test
Aliases :
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA