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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Porin Monoclonal Antibody (16G9E6BC4)
catalog :
459500
quantity :
100 µg
price :
425 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
16G9E6BC4
reactivity :
Saccharomycetales, rice blast fungus, fission yeast, Saccharomyces cerevisiae S288C, human, brewer's yeast
application :
western blot, immunocytochemistry
more info or order :
citations: 24
Published Application/Species/Sample/DilutionReference
  • western blot; brewer's yeast; fig 2c
Taylor N, Swenson S, Harris N, Germany E, Fox J, Khalimonchuk O. The Assembly Factor Pet117 Couples Heme a Synthase Activity to Cytochrome Oxidase Assembly. J Biol Chem. 2017;292:1815-1825 pubmed publisher
  • western blot; brewer's yeast; 1:1000; fig 3a
Robertson A, Schaltz K, Neimanis K, Staples J, McDonald A. Heterologous expression of the Crassostrea gigas (Pacific oyster) alternative oxidase in the yeast Saccharomyces cerevisiae. J Bioenerg Biomembr. 2016;48:509-520 pubmed
  • western blot; rice blast fungus; 1:2000; fig 12
Zhong K, Li X, Le X, Kong X, Zhang H, Zheng X, et al. MoDnm1 Dynamin Mediating Peroxisomal and Mitochondrial Fission in Complex with MoFis1 and MoMdv1 Is Important for Development of Functional Appressorium in Magnaporthe oryzae. PLoS Pathog. 2016;12:e1005823 pubmed publisher
  • western blot; brewer's yeast; fig 1
Swenson S, Cannon A, Harris N, Taylor N, Fox J, Khalimonchuk O. Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes. J Biol Chem. 2016;291:10411-25 pubmed publisher
  • western blot; brewer's yeast; fig 2
Shirozu R, Yashiroda H, Murata S. Proteasome Impairment Induces Recovery of Mitochondrial Membrane Potential and an Alternative Pathway of Mitochondrial Fusion. Mol Cell Biol. 2016;36:347-62 pubmed publisher
  • western blot; brewer's yeast; fig 1
Bohovych I, Fernandez M, Rahn J, Stackley K, Bestman J, Anandhan A, et al. Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability. Sci Rep. 2015;5:13989 pubmed publisher
  • western blot; fission yeast; 1:1000; fig 4d
Santarriaga S, Petersen A, Ndukwe K, Brandt A, GERGES N, Bruns Scaglione J, et al. The Social Amoeba Dictyostelium discoideum Is Highly Resistant to Polyglutamine Aggregation. J Biol Chem. 2015;290:25571-8 pubmed publisher
  • immunocytochemistry; human
Niu H, Rikihisa Y. Investigating interference with apoptosis induction by bacterial proteins. Methods Mol Biol. 2014;1197:169-84 pubmed publisher
  • western blot; Saccharomycetales; 1:1000
Schroeder E, Shadel G. Crosstalk between mitochondrial stress signals regulates yeast chronological lifespan. Mech Ageing Dev. 2014;135:41-9 pubmed publisher
  • western blot; rice blast fungus; fig 4
Deng Y, Qu Z, Naqvi N. The role of snx41-based pexophagy in magnaporthe development. PLoS ONE. 2013;8:e79128 pubmed publisher
  • western blot; brewer's yeast; fig 3
Beach A, Richard V, Leonov A, Burstein M, Bourque S, Koupaki O, et al. Mitochondrial membrane lipidome defines yeast longevity. Aging (Albany NY). 2013;5:551-74 pubmed
  • western blot; brewer's yeast; fig 5
Richard V, Leonov A, Beach A, Burstein M, Koupaki O, Gomez Perez A, et al. Macromitophagy is a longevity assurance process that in chronologically aging yeast limited in calorie supply sustains functional mitochondria and maintains cellular lipid homeostasis. Aging (Albany NY). 2013;5:234-69 pubmed
  • western blot; brewer's yeast; 1:20,000; fig 5
Avalos J, Fink G, Stephanopoulos G. Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols. Nat Biotechnol. 2013;31:335-41 pubmed publisher
  • western blot; Saccharomycetales; 1:1000; fig 5
Chatenay Lapointe M, Shadel G. Repression of mitochondrial translation, respiration and a metabolic cycle-regulated gene, SLF1, by the yeast Pumilio-family protein Puf3p. PLoS ONE. 2011;6:e20441 pubmed publisher
  • western blot; brewer's yeast; 1:1000; fig 3
Lin H, Li L, Jia X, Ward D, Kaplan J. Genetic and biochemical analysis of high iron toxicity in yeast: iron toxicity is due to the accumulation of cytosolic iron and occurs under both aerobic and anaerobic conditions. J Biol Chem. 2011;286:3851-62 pubmed publisher
Montllor Albalate C, Colin A, Chandrasekharan B, Bolaji N, Andersen J, Wayne Outten F, et al. Extra-mitochondrial Cu/Zn superoxide dismutase (Sod1) is dispensable for protection against oxidative stress but mediates peroxide signaling in Saccharomyces cerevisiae. Redox Biol. 2019;21:101064 pubmed publisher
Vigié P, Cougouilles E, Bhatia Kiššová I, Salin B, Blancard C, Camougrand N. The mitochondrial phosphatidylserine decarboxylase Psd1 is involved in nitrogen starvation-induced mitophagy in yeast. J Cell Sci. 2019;132: pubmed publisher
Sreelatha A, Yee S, Lopez V, Park B, Kinch L, Pilch S, et al. Protein AMPylation by an Evolutionarily Conserved Pseudokinase. Cell. 2018;175:809-821.e19 pubmed publisher
Herwaldt E, Rivett E, White A, Hegg E. Cox15 interacts with the cytochrome bc 1 dimer within respiratory supercomplexes as well as in the absence of cytochrome c oxidase. J Biol Chem. 2018;293:16426-16439 pubmed publisher
Wu X, Li L, Jiang H. Mitochondrial inner-membrane protease Yme1 degrades outer-membrane proteins Tom22 and Om45. J Cell Biol. 2018;217:139-149 pubmed publisher
Gomes F, Palma F, Barros M, Tsuchida E, Turano H, Alegria T, et al. Proteolytic cleavage by the inner membrane peptidase (IMP) complex or Oct1 peptidase controls the localization of the yeast peroxiredoxin Prx1 to distinct mitochondrial compartments. J Biol Chem. 2017;292:17011-17024 pubmed publisher
Bannon A, Kent J, Forquer I, Town A, Klug L, McCann K, et al. Biochemical, Molecular, and Clinical Characterization of Succinate Dehydrogenase Subunit A Variants of Unknown Significance. Clin Cancer Res. 2017;23:6733-6743 pubmed publisher
Deng Y, Qu Z, Naqvi N. Twilight, a Novel Circadian-Regulated Gene, Integrates Phototropism with Nutrient and Redox Homeostasis during Fungal Development. PLoS Pathog. 2015;11:e1004972 pubmed publisher
He Y, Deng Y, Naqvi N. Atg24-assisted mitophagy in the foot cells is necessary for proper asexual differentiation in Magnaporthe oryzae. Autophagy. 2013;9:1818-27 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Porin Monoclonal Antibody (16G9E6BC4)
Catalog # :
459500
Quantity :
100 µg
Price :
425 USD
Clonality :
Monoclonal
Purity :
IgG fraction
Host :
Mouse
Reactivity :
Yeast
Applications :
Western Blot: 1.0 µg/mL
Species :
Yeast
Clone :
16G9E6BC4
Isotype :
IgG1, kappa
Storage :
4° C, do not freeze
Description :
Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC constitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.
Immunogen :
Full length native protein (purified) corresponding to Saccharomyces cerevisiae VDAC1/Porin
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1.0 µg/mL
Aliases :
AL033343; BR1-VDAC; brain-derived voltage-dependent anion channel 1; hVDAC1; MGC111064; Mitochondrial outer membrane protein porin 1; Mitochondrial Porin; mVDAC1; mVDAC5; N2441; OMP2; Outer mitochondrial membrane protein porin 1; plasmalemmal porin; POR1; PORIN; Porin 31HL; porin 31HM; porin POR1; PORIN-31-HL; rVDAC1; VD; VDAC; VDAC1; VDAC-1; Vdac5; VDAC-5; voltage dependent anion channel 1; voltage-dependent anion channel 1; voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 5; YNL055C; YNL2441C
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA