This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
COX3 Monoclonal Antibody (DA5BC4)
catalog :
459300
quantity :
100 ug
price :
US 524.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DA5BC4

The same clone is also sold as:
reactivity :
Saccharomyces cerevisiae S288C, human, mouse, rat
application :
western blot
citations: 4
Reference
Timón Gómez A, Garlich J, Stuart R, Ugalde C, Barrientos A. Distinct Roles of Mitochondrial HIGD1A and HIGD2A in Respiratory Complex and Supercomplex Biogenesis. Cell Rep. 2020;31:107607 pubmed publisher
Strogolova V, Hoang N, Hosler J, Stuart R. The yeast mitochondrial proteins Rcf1 and Rcf2 support the enzymology of the cytochrome c oxidase complex and generation of the proton motive force. J Biol Chem. 2019;294:4867-4877 pubmed publisher
Box J, Kaur J, Stuart R. MrpL35, a mitospecific component of mitoribosomes, plays a key role in cytochrome c oxidase assembly. Mol Biol Cell. 2017;28:3489-3499 pubmed publisher
Garlich J, Strecker V, Wittig I, Stuart R. Mutational Analysis of the QRRQ Motif in the Yeast Hig1 Type 2 Protein Rcf1 Reveals a Regulatory Role for the Cytochrome c Oxidase Complex. J Biol Chem. 2017;292:5216-5226 pubmed publisher
product information
Product Type :
Antibody
Product Name :
COX3 Monoclonal Antibody (DA5BC4)
Catalog # :
459300
Quantity :
100 ug
Price :
US 524.00
Clonality :
Monoclonal
Purity :
IgG fraction
Host :
Mouse
Reactivity :
Human, Mouse, Rat, Yeast
Applications :
Western Blot: 2-4 ug/mL
Species :
Human, Mouse, Rat, Yeast
Clone :
DA5BC4
Isotype :
IgG2a, kappa
Storage :
4 C, do not freeze
Description :
COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
Immunogen :
Full length native Yeast Cytochrome C Oxidase subunit III
Format :
Liquid
Applications w/Dilutions :
Western Blot: 2-4 ug/mL
Aliases :
ACI60_gp01; Co3; Coiii; COX3; COXIII; cytchrome c oxidase sububnit 3; Cytochrome c oxidase polypeptide III; Cytochrome c oxidase subunit 3; cytochrome c oxidase subunit III; mitochondrially encoded cytochrome c oxidase III; Mtco3; mt-Co3; OXI2; Q0275
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA