Published Application/Species/Sample/Dilution | Reference |
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- western blot; mouse; loading ...; fig 1c
| Busch J, Cipullo M, Atanassov I, Bratic A, Silva Ramos E, Schondorf T, et al. MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition. Cell Rep. 2019;29:1728-1738.e9 pubmed publisher
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- western blot; mouse; loading ...; fig 2a
| Hammerschmidt P, Ostkotte D, Nolte H, Gerl M, Jais A, Brunner H, et al. CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity. Cell. 2019;177:1536-1552.e23 pubmed publisher
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- western blot; human; loading ...; fig 2a
| Richter F, Dennerlein S, Nikolov M, Jans D, Naumenko N, Aich A, et al. ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. J Cell Biol. 2019;218:598-614 pubmed publisher
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- western blot; mouse; loading ...; fig 6b
| Schatton D, Pla Martín D, Marx M, Hansen H, Mourier A, Nemazanyy I, et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017;216:675-693 pubmed publisher
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- western blot; rat; 1:2000; loading ...; fig 1
| Aukrust I, Rosenberg L, Ankerud M, Bertelsen V, Hollås H, Saraste J, et al. Post-translational modifications of Annexin A2 are linked to its association with perinuclear nonpolysomal mRNP complexes. FEBS Open Bio. 2017;7:160-173 pubmed publisher
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- western blot; rat; 1:1000; loading ...; fig 6d
| Merdzo I, Rutkai I, Sure V, McNulty C, Katakam P, Busija D. Impaired Mitochondrial Respiration in Large Cerebral Arteries of Rats with Type 2 Diabetes. J Vasc Res. 2017;54:1-12 pubmed publisher
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- western blot; human; 1:500; loading ...; fig 2
| Cabre R, Naudi A, Dominguez Gonzalez M, Ayala V, Jove M, Mota Martorell N, et al. Sixty years old is the breakpoint of human frontal cortex aging. Free Radic Biol Med. 2017;103:14-22 pubmed publisher
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- western blot; human; fig 1j
| Lorendeau D, Rinaldi G, Boon R, Spincemaille P, Metzger K, Jäger C, et al. Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors. Metab Eng. 2017;43:187-197 pubmed publisher
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- immunoprecipitation; mouse; loading ...; fig s6c
- western blot; mouse; 1:10,000; loading ...; fig s6c
| Cao L, Riascos Bernal D, Chinnasamy P, Dunaway C, Hou R, Pujato M, et al. Control of mitochondrial function and cell growth by the atypical cadherin Fat1. Nature. 2016;539:575-578 pubmed publisher
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- western blot; human; loading ...; fig 5a
| Richter Dennerlein R, Oeljeklaus S, Lorenzi I, Ronsör C, Bareth B, Schendzielorz A, et al. Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein. Cell. 2016;167:471-483.e10 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 3a
| Lauritzen K, Hasan Olive M, Regnell C, Kleppa L, Scheibye Knudsen M, Gjedde A, et al. A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain. Neurobiol Aging. 2016;48:34-47 pubmed publisher
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- western blot; mouse; fig 1d
| D Andrea A, Gritti I, Nicoli P, Giorgio M, Doni M, Conti A, et al. The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas. Oncotarget. 2016;7:72415-72430 pubmed publisher
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- western blot; human; loading ...; fig 2b
| Cenini G, Rüb C, Bruderek M, Voos W. Amyloid ?-peptides interfere with mitochondrial preprotein import competence by a coaggregation process. Mol Biol Cell. 2016;27:3257-3272 pubmed
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- western blot; mouse; 1:1000; fig 4
| Winter L, Wittig I, Peeva V, Eggers B, Heidler J, Chevessier F, et al. Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in skeletal muscle tissue. Acta Neuropathol. 2016;132:453-73 pubmed publisher
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- western blot; mouse; 1:5000; loading ...; fig 1b
| Garaude J, Acin Perez R, Martínez Cano S, Enamorado M, Ugolini M, Nistal Villán E, et al. Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense. Nat Immunol. 2016;17:1037-1045 pubmed publisher
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- western blot; mouse; fig 6
| Inoue T, Ikeda M, Ide T, Fujino T, Matsuo Y, Arai S, et al. Twinkle overexpression prevents cardiac rupture after myocardial infarction by alleviating impaired mitochondrial biogenesis. Am J Physiol Heart Circ Physiol. 2016;311:H509-19 pubmed publisher
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- western blot; mouse; 1:1000; fig 3
| Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, et al. Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep. 2016;17:953-64 pubmed publisher
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- western blot; human; fig 4
| Winter L, Türk M, Harter P, Mittelbronn M, Kornblum C, Norwood F, et al. Downstream effects of plectin mutations in epidermolysis bullosa simplex with muscular dystrophy. Acta Neuropathol Commun. 2016;4:44 pubmed publisher
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- western blot; mouse; 1:5000; fig 5
| Horton J, Martin O, Lai L, Riley N, Richards A, Vega R, et al. Mitochondrial protein hyperacetylation in the failing heart. JCI Insight. 2016;2: pubmed
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- western blot; human; 1:5000; fig s1
| Chang H, Wu R, Shang M, Sato T, Chen C, Shapiro J, et al. Reduction in mitochondrial iron alleviates cardiac damage during injury. EMBO Mol Med. 2016;8:247-67 pubmed publisher
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- western blot; rat; 1:1000; fig 6
| Merdzo I, Rutkai I, Tokés T, Sure V, Katakam P, Busija D. The mitochondrial function of the cerebral vasculature in insulin-resistant Zucker obese rats. Am J Physiol Heart Circ Physiol. 2016;310:H830-8 pubmed publisher
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- western blot; mouse; fig s3a
| Wai T, GarcÃa Prieto J, Baker M, Merkwirth C, Benit P, Rustin P, et al. Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice. Science. 2015;350:aad0116 pubmed publisher
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- western blot; mouse; fig s1
| Korwitz A, Merkwirth C, Richter Dennerlein R, Tröder S, Sprenger H, Quirós P, et al. Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria. J Cell Biol. 2016;212:157-66 pubmed publisher
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- western blot; rat; 1:1000
| Rutkai I, Dutta S, Katakam P, Busija D. Dynamics of enhanced mitochondrial respiration in female compared with male rat cerebral arteries. Am J Physiol Heart Circ Physiol. 2015;309:H1490-500 pubmed publisher
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| Brandauer J, Andersen M, Kellezi H, Risis S, Frøsig C, Vienberg S, et al. AMP-activated protein kinase controls exercise training- and AICAR-induced increases in SIRT3 and MnSOD. Front Physiol. 2015;6:85 pubmed publisher
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| Ikeda M, Ide T, Fujino T, Arai S, Saku K, Kakino T, et al. Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress. PLoS ONE. 2015;10:e0119687 pubmed publisher
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| Schüll S, Günther S, Brodesser S, Seeger J, Tosetti B, Wiegmann K, et al. Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6. Cell Death Dis. 2015;6:e1691 pubmed publisher
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- western blot; mouse; 1:1000; fig 5
| Zheng H, Fu J, Xue P, Zhao R, Dong J, Liu D, et al. CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion. Antioxid Redox Signal. 2015;22:819-31 pubmed publisher
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- western blot; mouse; fig 2
| Rivera Torres J, Acin Perez R, Cabezas Sánchez P, Osorio F, Gonzalez Gomez C, Megias D, et al. Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture. J Proteomics. 2013;91:466-77 pubmed publisher
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- immunocytochemistry; mouse; fig 3
| Springer H, Schramm M, Taylor G, Howard J. Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-?-induced mouse cells. J Immunol. 2013;191:1765-74 pubmed publisher
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- western blot; rat; 1:10,000; fig 5
| Wappler E, Institoris A, Dutta S, Katakam P, Busija D. Mitochondrial dynamics associated with oxygen-glucose deprivation in rat primary neuronal cultures. PLoS ONE. 2013;8:e63206 pubmed publisher
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- immunocytochemistry; human; 10 ug/ml; fig 8
| Pircher H, Straganz G, Ehehalt D, Morrow G, Tanguay R, Jansen Durr P. Identification of human fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) as a novel mitochondrial acylpyruvase. J Biol Chem. 2011;286:36500-8 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; 1:1000; fig 1
| Lauritzen K, Cheng C, Wiksen H, Bergersen L, Klungland A. Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses. DNA Repair (Amst). 2011;10:639-53 pubmed publisher
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| Borna N, Kishita Y, Sakai N, Hamada Y, Kamagata K, Kohda M, et al. Leigh Syndrome Due to NDUFV1 Mutations Initially Presenting as LBSL. Genes (Basel). 2020;11: pubmed publisher
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| Bondy Chorney E, Abramchuk I, Nasser R, Holinier C, Denoncourt A, Baijal K, et al. A Broad Response to Intracellular Long-Chain Polyphosphate in Human Cells. Cell Rep. 2020;33:108318 pubmed publisher
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| Abed F, Brown M, Al Mahmood O, Dark M. SDHB and SDHA Immunohistochemistry in Canine Pheochromocytomas. Animals (Basel). 2020;10: pubmed publisher
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| Keller F, Bruch R, Schneider R, Meier Hubberten J, Hafner M, Rudolf R. A Scaffold-Free 3-D Co-Culture Mimics the Major Features of the Reverse Warburg Effect In Vitro. Cells. 2020;9: pubmed publisher
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| Koh J, Kim K, Park S, Kim Y, Kim J. PPARδ Attenuates Alcohol-Mediated Insulin Resistance by Enhancing Fatty Acid-Induced Mitochondrial Uncoupling and Antioxidant Defense in Skeletal Muscle. Front Physiol. 2020;11:749 pubmed publisher
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| Kishita Y, Shimura M, Kohda M, Akita M, Imai Okazaki A, Yatsuka Y, et al. A novel homozygous variant in MICOS13/QIL1 causes hepato-encephalopathy with mitochondrial DNA depletion syndrome. Mol Genet Genomic Med. 2020;8:e1427 pubmed publisher
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| Hernansanz Agustín P, Choya Foces C, Carregal Romero S, Ramos E, Oliva T, Villa Piña T, et al. Na+ controls hypoxic signalling by the mitochondrial respiratory chain. Nature. 2020;586:287-291 pubmed publisher
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| Yamamoto Y, Kasai A, Omori H, Takino T, Sugihara M, Umemoto T, et al. ERdj8 governs the size of autophagosomes during the formation process. J Cell Biol. 2020;219: pubmed publisher
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| Delavallée L, Mathiah N, Cabon L, Mazeraud A, Brunelle Navas M, Lerner L, et al. Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus. Mol Metab. 2020;40:101027 pubmed publisher
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| Timper K, Del Río Martín A, Cremer A, Bremser S, Alber J, Giavalisco P, et al. GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function. Cell Metab. 2020;31:1189-1205.e13 pubmed publisher
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| Acin Perez R, Benador I, Petcherski A, Veliova M, Benavides G, Lagarrigue S, et al. A novel approach to measure mitochondrial respiration in frozen biological samples. EMBO J. 2020;39:e104073 pubmed publisher
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| Hara T, Shibata Y, Amagai R, Okado Matsumoto A. Use of in-gel peroxidase assay for cytochrome c to visualize mitochondrial complexes III and IV. Biol Open. 2020;9: pubmed publisher
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| Emperador S, Garrido Pérez N, Amezcua Gil J, Gaudó P, Andrés Sanz J, Yubero D, et al. Molecular Characterization of New FBXL4 Mutations in Patients With mtDNA Depletion Syndrome. Front Genet. 2019;10:1300 pubmed publisher
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| Pesini A, Iglesias E, Bayona Bafaluy M, Garrido Pérez N, Meade P, Gaudó P, et al. Brain pyrimidine nucleotide synthesis and Alzheimer disease. Aging (Albany NY). 2019;11:8433-8462 pubmed publisher
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| Han J, Kim S, Ryu M, Jang Y, Lee M, Ju X, et al. Chloramphenicol Mitigates Oxidative Stress by Inhibiting Translation of Mitochondrial Complex I in Dopaminergic Neurons of Toxin-Induced Parkinson's Disease Model. Oxid Med Cell Longev. 2019;2019:4174803 pubmed publisher
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| Ikeda K, Horie Inoue K, Suzuki T, Hobo R, Nakasato N, Takeda S, et al. Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alterations and enhanced hypoxia tolerance. Nat Commun. 2019;10:4108 pubmed publisher
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| Lin S, Huang C, Gunda V, Sun J, Chellappan S, Li Z, et al. Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments. Cell Rep. 2019;28:2824-2836.e8 pubmed publisher
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| Merdzo I, Rutkai I, Sure V, Katakam P, Busija D. Effects of prolonged type 2 diabetes on mitochondrial function in cerebral blood vessels. Am J Physiol Heart Circ Physiol. 2019;317:H1086-H1092 pubmed publisher
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| Panhale A, Richter F, Ramirez F, Shvedunova M, Manke T, Mittler G, et al. CAPRI enables comparison of evolutionarily conserved RNA interacting regions. Nat Commun. 2019;10:2682 pubmed publisher
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| Deng J, Guo Y, Yuan F, Chen S, Yin H, Jiang X, et al. Autophagy inhibition prevents glucocorticoid-increased adiposity via suppressing BAT whitening. Autophagy. 2019;:1-15 pubmed publisher
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| Uchino S, Iida A, Sato A, Ishikawa K, Mimaki M, Nishino I, et al. A novel compound heterozygous variant of ECHS1 identified in a Japanese patient with Leigh syndrome. Hum Genome Var. 2019;6:19 pubmed publisher
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| Horton J, Davidson M, Kurishima C, Vega R, Powers J, Matsuura T, et al. The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense. JCI Insight. 2019;4: pubmed publisher
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| Nadeau L, Patten D, Caron A, Garneau L, Pinault Masson E, Foretz M, et al. IL-15 improves skeletal muscle oxidative metabolism and glucose uptake in association with increased respiratory chain supercomplex formation and AMPK pathway activation. Biochim Biophys Acta Gen Subj. 2019;1863:395-407 pubmed publisher
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| Sprenger H, Wani G, Hesseling A, König T, Patron M, MacVicar T, et al. Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med. 2019;11: pubmed publisher
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| Lo S, Macmillan Crow L, Parajuli N. Renal cold storage followed by transplantation impairs proteasome function and mitochondrial protein homeostasis. Am J Physiol Renal Physiol. 2019;316:F42-F53 pubmed publisher
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| Widdrington J, Gómez Durán A, Pyle A, Ruchaud Sparagano M, Scott J, Baudouin S, et al. Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses. Front Immunol. 2018;9:2217 pubmed publisher
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| Timper K, Paeger L, Sánchez Lasheras C, Varela L, Jais A, Nolte H, et al. Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity. Cell Rep. 2018;25:383-397.e10 pubmed publisher
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| Kauppila J, Bonekamp N, Mourier A, Isokallio M, Just A, Kauppila T, et al. Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res. 2018;46:6642-6669 pubmed publisher
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| Jia Y, Liu N, Viswakarma N, Sun R, Schipma M, Shang M, et al. PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism. Int J Mol Sci. 2018;19: pubmed publisher
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| Becker C, Kukat A, Szczepanowska K, Hermans S, Senft K, Brandscheid C, et al. CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis. EMBO Rep. 2018;19: pubmed publisher
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| Ravà M, D Andrea A, Nicoli P, Gritti I, Donati G, Doni M, et al. Therapeutic synergy between tigecycline and venetoclax in a preclinical model of MYC/BCL2 double-hit B cell lymphoma. Sci Transl Med. 2018;10: pubmed publisher
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| Saita S, Tatsuta T, Lampe P, König T, Ohba Y, Langer T. PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. EMBO J. 2018;37: pubmed publisher
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| Milosevic T, Payen V, Sonveaux P, Muccioli G, Tulkens P, Van Bambeke F. Mitochondrial Alterations (Inhibition of Mitochondrial Protein Expression, Oxidative Metabolism, and Ultrastructure) Induced by Linezolid and Tedizolid at Clinically Relevant Concentrations in Cultured Human HL-60 Promyelocytes and THP-1 Monocytes. Antimicrob Agents Chemother. 2018;62: pubmed publisher
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| Vazquez Fonseca L, Doimo M, Calderan C, Desbats M, Acosta M, Cerqua C, et al. Mutations in COQ8B (ADCK4) found in patients with steroid resistant nephrotic syndrome alter COQ8B function. Hum Mutat. 2017;: pubmed publisher
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| Kühl I, Miranda M, Atanassov I, Kuznetsova I, Hinze Y, Mourier A, et al. Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals. elife. 2017;6: pubmed publisher
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| Feichtinger R, Oláhová M, Kishita Y, Garone C, Kremer L, Yagi M, et al. Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies. Am J Hum Genet. 2017;101:525-538 pubmed publisher
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| Nakazawa H, Ikeda K, Shinozaki S, Kobayashi M, Ikegami Y, Fu M, et al. Burn-induced muscle metabolic derangements and mitochondrial dysfunction are associated with activation of HIF-1α and mTORC1: Role of protein farnesylation. Sci Rep. 2017;7:6618 pubmed publisher
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| Tezze C, Romanello V, Desbats M, Fadini G, Albiero M, Favaro G, et al. Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence. Cell Metab. 2017;25:1374-1389.e6 pubmed publisher
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| Shintaku J, Peterson J, Talbert E, Gu J, Ladner K, Williams D, et al. MyoD Regulates Skeletal Muscle Oxidative Metabolism Cooperatively with Alternative NF-?B. Cell Rep. 2016;17:514-526 pubmed publisher
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| Kumar V, Bouameur J, Bär J, Rice R, Hornig Do H, Roop D, et al. A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015;211:1057-75 pubmed publisher
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| Lee Y, Min C, Kim T, Song H, Lim Y, Kim D, et al. Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter. EMBO Rep. 2015;16:1318-33 pubmed publisher
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| Bakkar N, Ladner K, Canan B, Liyanarachchi S, Bal N, Pant M, et al. IKK? and alternative NF-?B regulate PGC-1? to promote oxidative muscle metabolism. J Cell Biol. 2012;196:497-511 pubmed publisher
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