Mouse Persephin Recombinant Protein, PeproTech | Invitrogen 450-35-20UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Mouse Persephin Recombinant Protein, PeproTech

catalog :

450-35-20UG

quantity :

20 ug

price :

US 227.00

citations: 2

Reference
Gadomski S, Fielding C, Garc xed a Garc xed a A, Korn C, Kapeni C, Ashraf S, et al. A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise. Cell Stem Cell. 2022;29:528-544.e9 pubmed publisher
Cohen S, Sazan H, Kenigsberg A, Schori H, Piperno S, Shpaisman H, et al. Large-scale acoustic-driven neuronal patterning and directed outgrowth. Sci Rep. 2020;10:4932 pubmed publisher

product information

Product Type :

Protein

Product Name :

Mouse Persephin Recombinant Protein, PeproTech

Catalog # :

450-35-20UG

Quantity :

20 ug

Price :

US 227.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Mouse

Applications :

Functional Assay: Assay-dependent

Species :

Mouse

Storage :

-20 C

Description :

Persephin is a disulfide-linked, homodimeric, neurotrophic factor structurally related to GDNF, artemin, and neurturin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Persephin signals through a multicomponent receptor system, composed of RET and one of four GFR alpha (alpha1-alpha4) receptors. The GFRalpha4 was first identified in chicken, and was later shown to be the preferential binding subunit for persephin. Persephin promotes the survival of ventral midbrain dopaminergic neurons and motor neurons after sciatic nerve oxotomy, and, like GDNF, promotes ureteric bud branching. However, in contrast to GDNF and neurturin, persephin does not support the survival of peripheral neurons.

Format :

Lyophilized

Applications w/Dilutions :

Functional Assay: Assay-dependent

Aliases :

Persephin; PSP; Pspn