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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cytochrome C Monoclonal Antibody (37BA11)
catalog :
45-6100
quantity :
100 µg
price :
US 458.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
37BA11
reactivity :
human, mouse, rat, bovine, roundworm
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 1
Tamada H, Kiryu Seo S, Hosokawa H, Ohta K, Ishihara N, Nomura M, et al. Three-dimensional analysis of somatic mitochondrial dynamics in fission-deficient injured motor neurons using FIB/SEM. J Comp Neurol. 2017;525:2535-2548 pubmed publisher
  • immunohistochemistry; mouse; 1:300; loading ...; fig 2c
  • western blot; mouse; 1:2000; loading ...; fig 2e
Wang X, Wang L, Sun Y, Li R, Deng J, Deng J. DNA methylation and histone deacetylation regulating insulin sensitivity due to chronic cold exposure. Cryobiology. 2017;74:36-42 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; fig s2
Lauritzen K, Hasan Olive M, Regnell C, Kleppa L, Scheibye Knudsen M, Gjedde A, et al. A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain. Neurobiol Aging. 2016;48:34-47 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
Sharma P, Abbasi C, Lazic S, Teng A, Wang D, Dubois N, et al. Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nat Commun. 2015;6:8391 pubmed publisher
  • western blot; bovine
Althoff T, Mills D, Popot J, Kuhlbrandt W. Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1. EMBO J. 2011;30:4652-64 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 1
Lauritzen K, Cheng C, Wiksen H, Bergersen L, Klungland A. Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses. DNA Repair (Amst). 2011;10:639-53 pubmed publisher
Chen Y, Wang P, Huang B, Chen Y, Lee W, Chen Y. 16-Hydroxycleroda-3,13-dien-15,16-olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways. Molecules. 2020;25: pubmed publisher
Fu B, Xue W, Zhang H, Zhang R, Feldman K, Zhao Q, et al. MicroRNA-325-3p Facilitates Immune Escape of Mycobacterium tuberculosis through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 Signaling. MBio. 2020;11: pubmed publisher
Matia González A, Laing E, Gerber A. Conserved mRNA-binding proteomes in eukaryotic organisms. Nat Struct Mol Biol. 2015;22:1027-33 pubmed publisher
Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed publisher
Nedosekin D, Galanzha E, Ayyadevara S, Shmookler Reis R, Zharov V. Photothermal confocal spectromicroscopy of multiple cellular chromophores and fluorophores. Biophys J. 2012;102:672-81 pubmed publisher
Yang H, Brosel S, Acin Perez R, Slavkovich V, Nishino I, Khan R, et al. Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in Sco2. Hum Mol Genet. 2010;19:170-80 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Cytochrome C Monoclonal Antibody (37BA11)
Catalog # :
45-6100
Quantity :
100 µg
Price :
US 458.00
Clonality :
Monoclonal
Purity :
IgG fraction
Host :
Mouse
Reactivity :
Bovine, C. elegans, Human, Mouse, Rat
Applications :
Flow Cytometry: 1 µg/mL, Immunocytochemistry: 0.5-2 µg/mL, Western Blot: 0.25-1 µg/mL
Species :
Bovine, C. elegans, Human, Mouse, Rat
Clone :
37BA11
Isotype :
IgG2a, kappa
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
Immunogen :
Bovine heart Cytochrome C
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 µg/mL, Immunocytochemistry: 0.5-2 µg/mL, Western Blot: 0.25-1 µg/mL
Aliases :
CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA