CD123 Monoclonal Antibody (6H6), PerCP-Cyanine5.5, eBioscience | Invitrogen 45-1239-41 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD123 Monoclonal Antibody (6H6), PerCP-Cyanine5.5, eBioscience

catalog :

45-1239-41

quantity :

25 Tests

price :

US 159

clonality :

monoclonal

host :

mouse

conjugate :

PerCP/Cy5.5

clone name :

6H6

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Maney N, Reynolds G, Krippner Heidenreich A, Hilkens C. Dendritic cell maturation and survival are differentially regulated by TNFR1 and TNFR2. J Immunol. 2014;193:4914-4923 pubmed publisher
flow cytometry; human; fig s5	Ataide M, Andrade W, Zamboni D, Wang D, Souza M, Franklin B, et al. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection. PLoS Pathog. 2014;10:e1003885 pubmed publisher
	Baumgaertner P, Sankar M, Herrera F, Benedetti F, Barras D, Thierry A, et al. Unsupervised Analysis of Flow Cytometry Data in a Clinical Setting Captures Cell Diversity and Allows Population Discovery. Front Immunol. 2021;12:633910 pubmed publisher
	Nguyen M, Hosokawa K, Yoroidaka T, Maruyama H, Espinoza J, Elbadry M, et al. Resistance of KIR Ligand-Missing Leukocytes to NK Cells In Vivo in Patients with Acquired Aplastic Anemia. Immunohorizons. 2020;4:430-441 pubmed publisher
	PLUM T, Wang X, Rettel M, Krijgsveld J, Feyerabend T, Rodewald H. Human Mast Cell Proteome Reveals Unique Lineage, Putative Functions, and Structural Basis for Cell Ablation. Immunity. 2020;52:404-416.e5 pubmed publisher
	Bastian O, Croes M, Alblas J, Koenderman L, Leenen L, Blokhuis T. Neutrophils Inhibit Synthesis of Mineralized Extracellular Matrix by Human Bone Marrow-Derived Stromal Cells In Vitro. Front Immunol. 2018;9:945 pubmed publisher
	Jiang A, Jiang J, Wei J, Guo M, Qin Y, Guo Q, et al. Human Mucosal Mast Cells Capture HIV-1 and Mediate Viral trans-Infection of CD4+ T Cells. J Virol. 2015;90:2928-37 pubmed publisher
	Jiang A, Jiang J, Guo M, Jin Y, Li Y, Wang J. Human Blood-Circulating Basophils Capture HIV-1 and Mediate Viral trans-Infection of CD4+ T Cells. J Virol. 2015;89:8050-62 pubmed publisher
	Derkow K, Bauer J, Hecker M, Paap B, Thamilarasan M, Koczan D, et al. Multiple sclerosis: modulation of toll-like receptor (TLR) expression by interferon-? includes upregulation of TLR7 in plasmacytoid dendritic cells. PLoS ONE. 2013;8:e70626 pubmed publisher
	Compte N, Zouaoui Boudjeltia K, Vanhaeverbeek M, De Breucker S, Tassignon J, Trelcat A, et al. Frailty in old age is associated with decreased interleukin-12/23 production in response to toll-like receptor ligation. PLoS ONE. 2013;8:e65325 pubmed publisher
	Xu W, He B, Chiu A, Chadburn A, Shan M, Buldys M, et al. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI. Nat Immunol. 2007;8:294-303 pubmed
	Peduzzi E, Groeper C, Schütte D, Zajac P, Rondini S, Mensah Quainoo E, et al. Local activation of the innate immune system in Buruli ulcer lesions. J Invest Dermatol. 2007;127:638-45 pubmed
	Assaf C, Gellrich S, Whittaker S, Robson A, Cerroni L, Massone C, et al. CD56-positive haematological neoplasms of the skin: a multicentre study of the Cutaneous Lymphoma Project Group of the European Organisation for Research and Treatment of Cancer. J Clin Pathol. 2007;60:981-9 pubmed
	Jaye D, Geigerman C, Herling M, Eastburn K, Waller E, Jones D. Expression of the plasmacytoid dendritic cell marker BDCA-2 supports a spectrum of maturation among CD4+ CD56+ hematodermic neoplasms. Mod Pathol. 2006;19:1555-62 pubmed

product information

Product Type :

Antibody

Product Name :

CD123 Monoclonal Antibody (6H6), PerCP-Cyanine5.5, eBioscience

Catalog # :

45-1239-41

Quantity :

25 Tests

Price :

US 159

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.25 µg)/test

Species :

Human

Clone :

6H6

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.25 µg)/test

Aliases :

CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1

more info or order :

Invitrogen product webpage