CD14 Monoclonal Antibody (Sa2-8), PerCP-Cyanine5.5, eBioscience | Invitrogen 45-0141-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD14 Monoclonal Antibody (Sa2-8), PerCP-Cyanine5.5, eBioscience

catalog :

45-0141-82

quantity :

100 µg

price :

US 360.00

clonality :

monoclonal

host :

rat

conjugate :

PerCP/Cy5.5

clone name :

Sa2-8

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 43

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; tbl 1	Hersrud S, Kovács A, Pearce D. Antigen presenting cell abnormalities in the Cln3(-/-) mouse model of juvenile neuronal ceroid lipofuscinosis. Biochim Biophys Acta. 2016;1862:1324-36 pubmed publisher
flow cytometry; mouse	Longman R, Diehl G, Victorio D, Huh J, Galan C, Miraldi E, et al. CX?CR1? mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. J Exp Med. 2014;211:1571-83 pubmed publisher
	Wang Y, Jing L, Lei X, Ma Z, Li B, Shi Y, et al. Umbilical cord mesenchymal stem cell-derived apoptotic extracellular vesicles ameliorate cutaneous wound healing in type 2 diabetic mice via macrophage pyroptosis inhibition. Stem Cell Res Ther. 2023;14:257 pubmed publisher
	Wu Y, Fan X, Yu H, Liu J, Duan Y, Zhang S, et al. Macrophage polarization is involved in liver fibrosis induced by β 1-adrenoceptor autoantibody. Acta Biochim Biophys Sin (Shanghai). 2022;54:1100-1112 pubmed publisher
	Flamant M, Mougenot N, Balse E, Le Fevre L, Atassi F, Gautier E, et al. Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure. Sci Rep. 2021;11:17982 pubmed publisher
	Shen T, Chen C, Jhan M, Tseng P, Lin C. CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain. Front Cell Infect Microbiol. 2020;10:557610 pubmed publisher
	Xue J, Xu L, Zhu H, Bai M, Li X, Zhao Z, et al. CD14+CD16- monocytes are the main precursors of osteoclasts in rheumatoid arthritis via expressing Tyro3TK. Arthritis Res Ther. 2020;22:221 pubmed publisher
	Lee J, Hall J, Kroehling L, Wu L, Najar T, Nguyen H, et al. Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease. Cell. 2020;180:79-91.e16 pubmed publisher
	Aloor J, Azzam K, Guardiola J, Gowdy K, Madenspacher J, Gabor K, et al. Leucine-rich repeats and calponin homology containing 4 (Lrch4) regulates the innate immune response. J Biol Chem. 2019;294:1997-2008 pubmed publisher
	Xiao T, Wu S, Yan C, Zhao C, Jin H, Yan N, et al. Butyrate upregulates the TLR4 expression and the phosphorylation of MAPKs and NK-κB in colon cancer cell in vitro. Oncol Lett. 2018;16:4439-4447 pubmed publisher
	Wu H, Xu X, Li J, Gong J, Li M. TIM‑4 blockade of KCs combined with exogenous TGF‑β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts. Int J Mol Med. 2018;42:346-358 pubmed publisher
	Bi L, Sun L, Jin Z, Zhang S, Shen Z. MicroRNA-10a/b are regulators of myeloid differentiation and acute myeloid leukemia. Oncol Lett. 2018;15:5611-5619 pubmed publisher
	Schappe M, Szteyn K, Stremska M, Mendu S, Downs T, Seegren P, et al. Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation. Immunity. 2018;48:59-74.e5 pubmed publisher
	Pal B, Chen Y, Vaillant F, Jamieson P, Gordon L, Rios A, et al. Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling. Nat Commun. 2017;8:1627 pubmed publisher
	Thevaranjan N, Puchta A, Schulz C, Naidoo A, Szamosi J, Verschoor C, et al. Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction. Cell Host Microbe. 2017;21:455-466.e4 pubmed publisher
	Mucci A, Kunkiel J, Suzuki T, Brennig S, Glage S, Kühnel M, et al. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency. Stem Cell Reports. 2016;7:292-305 pubmed publisher
	Baliram R, Latif R, Morshed S, Zaidi M, Davies T. T3 Regulates a Human Macrophage-Derived TSH-? Splice Variant: Implications for Human Bone Biology. Endocrinology. 2016;157:3658-67 pubmed publisher
	Tan Y, Zanoni I, Cullen T, Goodman A, Kagan J. Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria. Immunity. 2015;43:909-22 pubmed publisher
	Tran C, Stary C, Schilling J, Bentley B, Patel H, Roth D. Role of caveolin-3 in lymphocyte activation. Life Sci. 2015;121:35-9 pubmed publisher
	Crane M, Daley J, Van Houtte O, Brancato S, Henry W, Albina J. The monocyte to macrophage transition in the murine sterile wound. PLoS ONE. 2014;9:e86660 pubmed publisher
	Roehrich M, Spicher A, Milano G, Vassalli G. Characterization of cardiac-resident progenitor cells expressing high aldehyde dehydrogenase activity. Biomed Res Int. 2013;2013:503047 pubmed publisher
	Jux B, Staratschek Jox A, Penninger J, Schultze J, Kolanus W. Vav1 regulates MHCII expression in murine resting and activated B cells. Int Immunol. 2013;25:307-17 pubmed publisher
	Hagman D, Kuzma J, Larson I, Foster Schubert K, Kuan L, Cignarella A, et al. Characterizing and quantifying leukocyte populations in human adipose tissue: impact of enzymatic tissue processing. J Immunol Methods. 2012;386:50-9 pubmed publisher
	Satpathy A, Kc W, Albring J, Edelson B, Kretzer N, Bhattacharya D, et al. Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages. J Exp Med. 2012;209:1135-52 pubmed publisher
	Hasenberg M, Köhler A, Bonifatius S, Borucki K, Riek Burchardt M, Achilles J, et al. Rapid immunomagnetic negative enrichment of neutrophil granulocytes from murine bone marrow for functional studies in vitro and in vivo. PLoS ONE. 2011;6:e17314 pubmed publisher
	Michelow I, Lear C, Scully C, Prugar L, Longley C, Yantosca L, et al. High-dose mannose-binding lectin therapy for Ebola virus infection. J Infect Dis. 2011;203:175-9 pubmed publisher
	Marchlik E, Thakker P, Carlson T, Jiang Z, Ryan M, Marusic S, et al. Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality. J Leukoc Biol. 2010;88:1171-80 pubmed publisher
	Tanaka C, Fujimoto M, Hamaguchi Y, Sato S, Takehara K, Hasegawa M. Inducible costimulator ligand regulates bleomycin-induced lung and skin fibrosis in a mouse model independently of the inducible costimulator/inducible costimulator ligand pathway. Arthritis Rheum. 2010;62:1723-32 pubmed publisher
	Miellot Gafsou A, Biton J, Bourgeois E, Herbelin A, Boissier M, Bessis N. Early activation of invariant natural killer T cells in a rheumatoid arthritis model and application to disease treatment. Immunology. 2010;130:296-306 pubmed publisher
	Oliva C, Turnbough C, Kearney J. CD14-Mac-1 interactions in Bacillus anthracis spore internalization by macrophages. Proc Natl Acad Sci U S A. 2009;106:13957-62 pubmed publisher
	Tse M, Lane C, Mott K, Onlamoon N, Hsiao H, Perng G. ICAM-5 modulates cytokine/chemokine production in the CNS during the course of herpes simplex virus type 1 infection. J Neuroimmunol. 2009;213:12-9 pubmed publisher
	Cui J, Zhu N, Wang Q, Yu M, Feng J, Li Y, et al. p38 MAPK contributes to CD54 expression and the enhancement of phagocytic activity during macrophage development. Cell Immunol. 2009;256:6-11 pubmed publisher
	Blumenthal A, Kobayashi T, Pierini L, Banaei N, Ernst J, Miyake K, et al. RP105 facilitates macrophage activation by Mycobacterium tuberculosis lipoproteins. Cell Host Microbe. 2009;5:35-46 pubmed publisher
	Sun Q, Jin H, Bond J. Disruption of the meprin alpha and beta genes in mice alters homeostasis of monocytes and natural killer cells. Exp Hematol. 2009;37:346-56 pubmed publisher
	Nemoto E, Honda T, Kanaya S, Takada H, Shimauchi H. Expression of functional Toll-like receptors and nucleotide-binding oligomerization domain proteins in murine cementoblasts and their upregulation during cell differentiation. J Periodontal Res. 2008;43:585-93 pubmed publisher
	Brake D, Smith C. Flow cytometry on the stromal-vascular fraction of white adipose tissue. Methods Mol Biol. 2008;456:221-9 pubmed publisher
	Zhu N, Cui J, Qiao C, Li Y, Ma Y, Zhang J, et al. cAMP modulates macrophage development by suppressing M-CSF-induced MAPKs activation. Cell Mol Immunol. 2008;5:153-7 pubmed publisher
	Wu X, Yu G, Parks H, Hebert T, Goh B, Dietrich M, et al. Circadian mechanisms in murine and human bone marrow mesenchymal stem cells following dexamethasone exposure. Bone. 2008;42:861-70 pubmed publisher
	Wang R, Braughton K, Kretschmer D, Bach T, Queck S, Li M, et al. Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA. Nat Med. 2007;13:1510-4 pubmed
	Peng J, Kitchen S, West R, Sigler R, Eisenmann K, Alberts A. Myeloproliferative defects following targeting of the Drf1 gene encoding the mammalian diaphanous related formin mDia1. Cancer Res. 2007;67:7565-71 pubmed
	Petursdottir D, Hardardottir I. Dietary fish oil increases the number of splenic macrophages secreting TNF-alpha and IL-10 but decreases the secretion of these cytokines by splenic T cells from mice. J Nutr. 2007;137:665-70 pubmed
	Turner J, Langley R, Johnston K, Egerton G, Wanji S, Taylor M. Wolbachia endosymbiotic bacteria of Brugia malayi mediate macrophage tolerance to TLR- and CD40-specific stimuli in a MyD88/TLR2-dependent manner. J Immunol. 2006;177:1240-9 pubmed
	Brake D, Smith E, Mersmann H, Smith C, Robker R. ICAM-1 expression in adipose tissue: effects of diet-induced obesity in mice. Am J Physiol Cell Physiol. 2006;291:C1232-9 pubmed

product information

Product Type :

Antibody

Product Name :

CD14 Monoclonal Antibody (Sa2-8), PerCP-Cyanine5.5, eBioscience

Catalog # :

45-0141-82

Quantity :

100 µg

Price :

US 360.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test

Species :

Mouse

Clone :

Sa2-8

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test

Aliases :

CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14

more info or order :

Invitrogen product webpage