Phospho-S6 (Ser244, Ser247) Polyclonal Antibody | Invitrogen 44-923G product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-S6 (Ser244, Ser247) Polyclonal Antibody

catalog :

44-923G

quantity :

100 µL

price :

US 466

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse

application :

western blot, immunohistochemistry - frozen section, immunohistochemistry - free floating section

more info or order :

Invitrogen product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 7e	Sharma R, Ishimaru Y, Davison I, Ikegami K, Chien M, You H, et al. Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice. elife. 2017;6: pubmed publisher
immunohistochemistry - free floating section; mouse; loading ...; fig 1f	Tan C, Cooke E, Leib D, Lin Y, Daly G, Zimmerman C, et al. Warm-Sensitive Neurons that Control Body Temperature. Cell. 2016;167:47-59.e15 pubmed publisher
	Ryu H, Kim M, Park H, Choi H, Chung C. Stress-induced translation of KCNB1 contributes to the enhanced synaptic transmission of the lateral habenula. Front Cell Neurosci. 2023;17:1278847 pubmed publisher
	Weiss J, Vacher H, Trouillet A, Leinders Zufall T, Zufall F, Chamero P. Sensing and avoiding sick conspecifics requires Gαi2+ vomeronasal neurons. BMC Biol. 2023;21:152 pubmed publisher
	Hellysaz A, Svensson L, Hagbom M. Rotavirus Downregulates Tyrosine Hydroxylase in the Noradrenergic Sympathetic Nervous System in Ileum, Early in Infection and Simultaneously with Increased Intestinal Transit and Altered Brain Activities. MBio. 2022;13:e0138722 pubmed publisher
	Delorme J, Wang L, Kodoth V, Wang Y, Ma J, Jiang S, et al. Hippocampal neurons' cytosolic and membrane-bound ribosomal transcript profiles are differentially regulated by learning and subsequent sleep. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
	Autry A, Wu Z, Kapoor V, Kohl J, Bambah Mukku D, Rubinstein N, et al. Urocortin-3 neurons in the mouse perifornical area promote infant-directed neglect and aggression. elife. 2021;10: pubmed publisher
	Stern S, Azevedo E, Pomeranz L, Doerig K, Ivan V, Friedman J. Top-down control of conditioned overconsumption is mediated by insular cortex Nos1 neurons. Cell Metab. 2021;33:1418-1432.e6 pubmed publisher
	Caglar C, Friedman J. Restriction of food intake by PPP1R17-expressing neurons in the DMH. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
	Vihani A, Hu X, Gundala S, Koyama S, Block E, Matsunami H. Semiochemical responsive olfactory sensory neurons are sexually dimorphic and plastic. elife. 2020;9: pubmed publisher
	Nakahara T, Camargo A, Magalhães P, Souza M, Ribeiro P, Martins Netto P, et al. Peripheral oxytocin injection modulates vomeronasal sensory activity and reduces pup-directed aggression in male mice. Sci Rep. 2020;10:19943 pubmed publisher
	Azevedo E, Tan B, Pomeranz L, Ivan V, Fetcho R, Schneeberger M, et al. A limbic circuit selectively links active escape to food suppression. elife. 2020;9: pubmed publisher
	Carvalho V, Nakahara T, Souza M, Cardozo L, Trintinalia G, Pissinato L, et al. Representation of Olfactory Information in Organized Active Neural Ensembles in the Hypothalamus. Cell Rep. 2020;32:108061 pubmed publisher
	Fischer E, Alvarez H, Lagerstrom K, McKinney J, Petrillo R, Ellis G, et al. Neural correlates of winning and losing fights in poison frog tadpoles. Physiol Behav. 2020;223:112973 pubmed publisher
	Jiang H, Gallet S, Klemm P, Scholl P, Folz Donahue K, Altmuller J, et al. MCH Neurons Regulate Permeability of the Median Eminence Barrier. Neuron. 2020;107:306-319.e9 pubmed publisher
	Håglin S, Berghard A, Bohm S. Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia. J Neurosci. 2020;40:4116-4129 pubmed publisher
	Jais A, Paeger L, Sotelo Hitschfeld T, Bremser S, Prinzensteiner M, Klemm P, et al. PNOCARC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding. Neuron. 2020;106:1009-1025.e10 pubmed publisher
	York R, Byrne A, Abdilleh K, Patil C, Streelman T, Finger T, et al. Behavioral evolution contributes to hindbrain diversification among Lake Malawi cichlid fish. Sci Rep. 2019;9:19994 pubmed publisher
	Azevedo E, POMERANZ L, Cheng J, Schneeberger M, Vaughan R, Stern S, et al. A Role of Drd2 Hippocampal Neurons in Context-Dependent Food Intake. Neuron. 2019;102:873-886.e5 pubmed publisher
	MILNER E, Do M. A Population Representation of Absolute Light Intensity in the Mammalian Retina. Cell. 2017;171:865-876.e16 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-S6 (Ser244, Ser247) Polyclonal Antibody

Catalog # :

44-923G

Quantity :

100 µL

Price :

US 466

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 1:1,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Immunogen :

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human RPS6 that contains serines 244 and 247. The sequence is conserved in mouse and rat.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

(Rp)S6; 40S ribosomal protein S6; air[8]; air8; anon-WO02059370.61; CG10944; CG10944-PA; CG10944-PB; Dmel CG10944; Dmel_CG10944; DS6; hemocytes enlarged; hen; l(1)air[8]; l(1)air8; l(1)hen; LD31286p; lethal(1)aberrant immune response[8]; lethal-(1)-haemocytes enlarged; lethal-aberrant-immune-response-8; M(1)7BC; M(1)7C; minute; minute (1) 7BC; OK/SW-cl.2; OTTHUMP00000021121; OTTHUMP00000021122; Phosphoprotein NP33; pp30; ribosomal protein S6; Rp S6; RP11-513M16.6; RPS6; RpS6-PA; RpS6-PB; RS6; S6; S6 ribosomal protein; S6R; Small ribosomal subunit protein eS6; wu:fa92e06; wu:fb64g06; zgc:92237

more info or order :

Invitrogen product webpage