| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; loading ...; fig 4c
| Sugiyama T, Murao N, Kadowaki H, Takao K, Miyakawa T, Matsushita Y, et al. ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function. iScience. 2021;24:102758 pubmed publisher |
- western blot; human; loading ...; fig s3f
| Guillén Boixet J, Kopach A, Holehouse A, Wittmann S, Jahnel M, Schlüßler R, et al. RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation. Cell. 2020;181:346-361.e17 pubmed publisher |
- western blot; rat; 1:500; loading ...; fig 7h
| Santos M, Anderson C, Neschen S, Zumbrennen Bullough K, Romney S, Kahle Stephan M, et al. Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification. Nat Commun. 2020;11:296 pubmed publisher |
- western blot; brewer's yeast; 1:1000; fig 3f
| Tye B, Commins N, Ryazanova L, Wühr M, Springer M, Pincus D, et al. Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness. elife. 2019;8: pubmed publisher |
- western blot; mouse; fig s2a
| Kaufman D, Papillon J, Larose L, Iwawaki T, Cybulsky A. Deletion of inositol-requiring enzyme-1? in podocytes disrupts glomerular capillary integrity and autophagy. Mol Biol Cell. 2017;28:1636-1651 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s3i
| Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig 1a
| Silva R, Sattlegger E, Castilho B. Perturbations in actin dynamics reconfigure protein complexes that modulate GCN2 activity and promote an eIF2 response. J Cell Sci. 2016;129:4521-4533 pubmed |
- western blot; rat; loading ...; fig 6a
| Ayuso M, Martínez Alonso E, Regidor I, Alcazar A. Stress Granule Induction after Brain Ischemia Is Independent of Eukaryotic Translation Initiation Factor (eIF) 2? Phosphorylation and Is Correlated with a Decrease in eIF4B and eIF4E Proteins. J Biol Chem. 2016;291:27252-27264 pubmed publisher |
- western blot; roundworm ; fig 1a
| Ferraz R, Camara H, De Souza E, Pinto S, Pinca A, Silva R, et al. IMPACT is a GCN2 inhibitor that limits lifespan in Caenorhabditis elegans. BMC Biol. 2016;14:87 pubmed |
- western blot; human; 1:1000; loading ...; fig 5d
- western blot; mouse; 1:1000; loading ...; fig 1c
| Khoutorsky A, Sorge R, Prager Khoutorsky M, Pawlowski S, Longo G, Jafarnejad S, et al. eIF2? phosphorylation controls thermal nociception. Proc Natl Acad Sci U S A. 2016;113:11949-11954 pubmed |
- western blot; human; loading ...; fig 5
| Mohammad S, Wolfe L, Stöbe P, Biskup S, Wainwright M, Melin Aldana H, et al. Infantile Cirrhosis, Growth Impairment, and Neurodevelopmental Anomalies Associated with Deficiency of PPP1R15B. J Pediatr. 2016;179:144-149.e2 pubmed publisher |
- western blot; mouse; 1:1000; fig 3
| Zhu S, Henninger K, McGrath B, Cavener D. PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility. PLoS ONE. 2016;11:e0162766 pubmed publisher |
- western blot; human; fig 8
| Nelson E, Schmidt K, Deflubé L, Doğanay S, Banadyga L, Olejnik J, et al. Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions. J Virol. 2016;90:7268-7284 pubmed publisher |
- western blot; mouse; fig 8
- western blot; cat; fig 1
| Humoud M, Doyle N, Royall E, Willcocks M, Sorgeloos F, van Kuppeveld F, et al. Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage. J Virol. 2016;90:6489-6501 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 3a
| Kainulainen M, Lau S, Samuel C, Hornung V, Weber F. NSs Virulence Factor of Rift Valley Fever Virus Engages the F-Box Proteins FBXW11 and ?-TRCP1 To Degrade the Antiviral Protein Kinase PKR. J Virol. 2016;90:6140-7 pubmed publisher |
- western blot; human; fig 2
| Zhong L, Wang L, Xu L, Liu Q, Jiang L, Zhi Y, et al. The cytotoxic effect of the NOS-mediated oxidative stress in MCF-7 cells after PbClâ‚‚ exposure. Environ Toxicol. 2016;31:601-8 pubmed publisher |
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| Ohkubo R, Mu W, Wang C, Song Z, Barthez M, Wang Y, et al. The hepatic integrated stress response suppresses the somatotroph axis to control liver damage in nonalcoholic fatty liver disease. Cell Rep. 2022;41:111803 pubmed publisher |
| Roberto Pinto A, Am xe9 rico M, Terenzi H, Silveira D. Inhibiting IRE-1 RNase signaling decreases HIV-1 Tat-induced inflammatory M1 state in microglial cells. Biochim Biophys Acta Gen Subj. 2022;1866:130219 pubmed publisher |
| Hurwitz B, Guzzi N, Gola A, Fiore V, Sendoel A, Nikolova M, et al. The integrated stress response remodels the microtubule-organizing center to clear unfolded proteins following proteotoxic stress. elife. 2022;11: pubmed publisher |
| Wang C, Angl xe8 s F, Balch W. Triangulating variation in the population to define mechanisms for precision management of genetic disease. Structure. 2022;30:1190-1207.e5 pubmed publisher |
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| Bai X, Zhou Y, Lin Q, Huang C, Zhang S, Carlson R, et al. Bio-nanoparticle based therapeutic vaccine induces immunogenic response against triple negative breast cancer. Am J Cancer Res. 2021;11:4141-4174 pubmed |
| Chen Y, Cao S, Chen H, Yin C, Xu X, Yang Z. Dexmedetomidine Preconditioning Reduces Myocardial Ischemia-Reperfusion Injury in Rats by Inhibiting the PERK Pathway. Arq Bras Cardiol. 2021;117:1134-1144 pubmed publisher |
| Hong J, Park E, Lee J, Lee Y, Rooney B, Park Y. Exercise training mitigates ER stress and UCP2 deficiency-associated coronary vascular dysfunction in atherosclerosis. Sci Rep. 2021;11:15449 pubmed publisher |
| Ohtsuka H, Kobayashi M, Shimasaki T, Sato T, Akanuma G, Kitaura Y, et al. Magnesium depletion extends fission yeast lifespan via general amino acid control activation. Microbiologyopen. 2021;10:e1176 pubmed publisher |
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| Mendes A, Gigan J, Rodríguez Rodrígues C, Choteau S, Sanséau D, Barros D, et al. Proteostasis in dendritic cells is controlled by the PERK signaling axis independently of ATF4. Life Sci Alliance. 2021;4: pubmed publisher |
| Muller R, Meacham Z, Ferguson L, Ingolia N. CiBER-seq dissects genetic networks by quantitative CRISPRi profiling of expression phenotypes. Science. 2020;370: pubmed publisher |
| Schneider K, Nelson G, Watson J, Morf J, Dalglish M, Luh L, et al. Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation. Cell Rep. 2020;32:108154 pubmed publisher |
| De Zoysa T, Phizicky E. Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequences. PLoS Genet. 2020;16:e1008893 pubmed publisher |
| Wuerth J, Habjan M, Kainulainen M, Berisha B, Bertheloot D, Superti Furga G, et al. eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition. MBio. 2020;11: pubmed publisher |
| Hong J, Hong S, Lee J, Park J, Eriksen J, Rooney B, et al. Exercise training ameliorates cerebrovascular dysfunction in a murine model of Alzheimer's disease: role of the P2Y2 receptor and endoplasmic reticulum stress. Am J Physiol Heart Circ Physiol. 2020;318:H1559-H1569 pubmed publisher |
| Ramesh R, Sattlegger E. Domain II of the translation elongation factor eEF1A is required for Gcn2 kinase inhibition. FEBS Lett. 2020;594:2266-2281 pubmed publisher |
| Alvarez Castelao B, Tom Dieck S, Fusco C, Donlin Asp P, Perez J, Schuman E. The switch-like expression of heme-regulated kinase 1 mediates neuronal proteostasis following proteasome inhibition. elife. 2020;9: pubmed publisher |
| Dörrbaum A, Alvarez Castelao B, Nassim Assir B, Langer J, Schuman E. Proteome dynamics during homeostatic scaling in cultured neurons. elife. 2020;9: pubmed publisher |
| Guo X, Aviles G, Liu Y, Tian R, Unger B, Lin Y, et al. Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway. Nature. 2020;579:427-432 pubmed publisher |
| Nyunt T, Britton M, Wanichthanarak K, Budamagunta M, Voss J, Wilson D, et al. Mitochondrial oxidative stress-induced transcript variants of ATF3 mediate lipotoxic brain microvascular injury. Free Radic Biol Med. 2019;143:25-46 pubmed publisher |
| Rodriguez C, Chun S, Mills R, Todd P. Translation of upstream open reading frames in a model of neuronal differentiation. BMC Genomics. 2019;20:391 pubmed publisher |
| An H, Ordureau A, Paulo J, Shoemaker C, Denic V, Harper J. TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress. Mol Cell. 2019;74:891-908.e10 pubmed publisher |
| Fusade Boyer M, Dupré G, Bessière P, Khiar S, Quentin Froignant C, Beck C, et al. Evaluation of the Antiviral Activity of Sephin1 Treatment and Its Consequences on eIF2α Phosphorylation in Response to Viral Infections. Front Immunol. 2019;10:134 pubmed publisher |
| Anglès F, Hutt D, Balch W. HDAC inhibitors rescue multiple disease-causing CFTR variants. Hum Mol Genet. 2019;28:1982-2000 pubmed publisher |
| Hodgson R, Varanda B, Ashe M, Allen K, Campbell S. Cellular eIF2B subunit localization: implications for the integrated stress response and its control by small molecule drugs. Mol Biol Cell. 2019;30:942-958 pubmed publisher |
| van Galen P, Mbong N, Kreso A, Schoof E, Wagenblast E, Ng S, et al. Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia. Cell Rep. 2018;25:1109-1117.e5 pubmed publisher |
| Krzyzosiak A, Sigurdardottir A, Luh L, Carrara M, Das I, Schneider K, et al. Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B. Cell. 2018;174:1216-1228.e19 pubmed publisher |
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| White M, Schroeder R, Zhu K, Xiong K, McConkey D. HRI-mediated translational repression reduces proteotoxicity and sensitivity to bortezomib in human pancreatic cancer cells. Oncogene. 2018;37:4413-4427 pubmed publisher |
| Diedrichs D, Gomez J, Huang C, Rutkowski D, Curtu R. A data-entrained computational model for testing the regulatory logic of the vertebrate unfolded protein response. Mol Biol Cell. 2018;29:1502-1517 pubmed publisher |
| Cubas Gaona L, Diaz Beneitez E, Ciscar M, Rodriguez J, Rodriguez D. Exacerbated Apoptosis of Cells Infected with Infectious Bursal Disease Virus upon Exposure to Interferon Alpha. J Virol. 2018;92: pubmed publisher |
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| Bettaieb A, Jiang J, Sasaki Y, Chao T, Kiss Z, Chen X, et al. Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice. Gastroenterology. 2015;149:468-80.e10 pubmed publisher |
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