| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 2a
| Shaaya M, Fauser J, Zhurikhina A, Conage Pough J, Huyot V, Brennan M, et al. Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity. elife. 2020;9: pubmed publisher |
- immunocytochemistry; human; fig 5d
| Chen X, Wanggou S, Bodalia A, Zhu M, Dong W, Fan J, et al. A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression. Neuron. 2018;100:799-815.e7 pubmed publisher |
- western blot; human; loading ...; fig s8a
| Mekhdjian A, Kai F, Rubashkin M, Prahl L, Przybyla L, McGregor A, et al. Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell. 2017;28:1467-1488 pubmed publisher |
- western blot; dogs; loading ...; fig 4c
| Zhang W, Gunst S. Non-muscle (NM) myosin heavy chain phosphorylation regulates the formation of NM myosin filaments, adhesome assembly and smooth muscle contraction. J Physiol. 2017;595:4279-4300 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 4D
| Oudin M, Miller M, Klazen J, Kosciuk T, Lussiez A, Hughes S, et al. MenaINV mediates synergistic cross-talk between signaling pathways driving chemotaxis and haptotaxis. Mol Biol Cell. 2016;27:3085-3094 pubmed |
- immunocytochemistry; human; fig 1
| Fokkelman M, Balcıoğlu H, Klip J, Yan K, Verbeek F, Danen E, et al. Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour. Sci Rep. 2016;6:31707 pubmed publisher |
- immunocytochemistry; rat; fig 1
| Harizanova J, Fermin Y, Malik Sheriff R, Wieczorek J, Ickstadt K, Grecco H, et al. Highly Multiplexed Imaging Uncovers Changes in Compositional Noise within Assembling Focal Adhesions. PLoS ONE. 2016;11:e0160591 pubmed publisher |
- immunocytochemistry; mouse; 1:100; fig 3
| Farrugia A, Calvo F. Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts. Small Gtpases. 2017;8:49-57 pubmed publisher |
- western blot; human; 1:1000; fig s1
| Freeman S, Christian S, Austin P, Iu I, Graves M, Huang L, et al. Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor. J Cell Sci. 2017;130:152-163 pubmed publisher |
- immunocytochemistry; mouse; 1:400; fig s3
| Kumar A, Ouyang M, van den Dries K, McGhee E, Tanaka K, Anderson M, et al. Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity. J Cell Biol. 2016;213:371-83 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig s1e
| Nader G, Ezratty E, Gundersen G. FAK, talin and PIPKI? regulate endocytosed integrin activation to polarize focal adhesion assembly. Nat Cell Biol. 2016;18:491-503 pubmed publisher |
- immunocytochemistry; human; 1:200; fig 6
- western blot; human; 1:500; fig 5
| Horton E, Humphries J, Stutchbury B, Jacquemet G, Ballestrem C, Barry S, et al. Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition. J Cell Biol. 2016;212:349-64 pubmed publisher |
- western blot; mouse; 1:1000; fig 5
| Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed publisher |
- immunohistochemistry; Xenopus laevis; 1:100; fig 4
| Tandon P, Wilczewski C, Williams C, Conlon F. The Lhx9-integrin pathway is essential for positioning of the proepicardial organ. Development. 2016;143:831-40 pubmed publisher |
| Filhol O, Hesse A, Bouin A, Albig xe8 s Rizo C, Jeanneret F, Battail C, et al. CK2β Is a Gatekeeper of Focal Adhesions Regulating Cell Spreading. Front Mol Biosci. 2022;9:900947 pubmed publisher |
| Fauser J, Huyot V, Matsche J, Szynal B, Alexeev Y, Kota P, et al. Dissecting protein tyrosine phosphatase signaling by engineered chemogenetic control of its activity. J Cell Biol. 2022;221: pubmed publisher |
| Ma J, Bi L, Spurlin J, Lwigale P. Nephronectin-integrin α8 signaling is required for proper migration of periocular neural crest cells during chick corneal development. elife. 2022;11: pubmed publisher |
| Guo Y, Mei F, Huang Y, Ma S, Wei Y, Zhang X, et al. Matrix stiffness modulates tip cell formation through the p-PXN-Rac1-YAP signaling axis. Bioact Mater. 2022;7:364-376 pubmed publisher |
| Malchiodi Z, Cao H, Gay M, Safronenka A, Bansal S, Tucker R, et al. Cholecystokinin Receptor Antagonist Improves Efficacy of Chemotherapy in Murine Models of Pancreatic Cancer by Altering the Tumor Microenvironment. Cancers (Basel). 2021;13: pubmed publisher |
| Weiße J, Rosemann J, Muller L, Kappler M, Eckert A, Glaß M, et al. Identification of lymphocyte cell-specific protein-tyrosine kinase (LCK) as a driver for invasion and migration of oral cancer by tumor heterogeneity exploitation. Mol Cancer. 2021;20:88 pubmed publisher |
| Arts J, Mahlandt E, Schimmel L, Grönloh M, Van Der Niet S, Klein B, et al. Endothelial Focal Adhesions Are Functional Obstacles for Leukocytes During Basolateral Crawling. Front Immunol. 2021;12:667213 pubmed publisher |
| Majstrowicz K, Honnert U, Nikolaus P, Schwarz V, Oeding S, Hemkemeyer S, et al. Coordination of mitochondrial and cellular dynamics by the actin-based motor Myo19. J Cell Sci. 2021;134: pubmed publisher |
| Wu Y, Huang Y, Zhang W, Gunst S. The proprotein convertase furin inhibits IL-13-induced inflammation in airway smooth muscle by regulating integrin-associated signaling complexes. Am J Physiol Lung Cell Mol Physiol. 2021;321:L102-L115 pubmed publisher |
| Mousson A, Legrand M, Steffan T, Vauchelles R, Carl P, Gies J, et al. Inhibiting FAK-Paxillin Interaction Reduces Migration and Invadopodia-Mediated Matrix Degradation in Metastatic Melanoma Cells. Cancers (Basel). 2021;13: pubmed publisher |
| Zink J, Frye M, Frömel T, Carlantoni C, John D, Schreier D, et al. EVL regulates VEGF receptor-2 internalization and signaling in developmental angiogenesis. EMBO Rep. 2021;22:e48961 pubmed publisher |
| Kilinc A, Han S, Barrett L, Anandasivam N, Nelson C. Integrin-linked kinase tunes cell-cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1. Mol Biol Cell. 2021;32:402-412 pubmed publisher |
| Lee Y, Finch Edmondson M, Cognart H, Zhu B, Song H, Low B, et al. Common and Unique Transcription Signatures of YAP and TAZ in Gastric Cancer Cells. Cancers (Basel). 2020;12: pubmed publisher |
| Chen K, Jiao X, Di Rocco A, Shen D, Xu S, Ertel A, et al. Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation. Cell Rep. 2020;32:108151 pubmed publisher |
| Zhang W, Gunst S. S100A4 is activated by RhoA and catalyses the polymerization of non-muscle myosin, adhesion complex assembly and contraction in airway smooth muscle. J Physiol. 2020;598:4573-4590 pubmed publisher |
| Huang Y, Gunst S. Phenotype transitions induced by mechanical stimuli in airway smooth muscle are regulated by differential interactions of parvin isoforms with paxillin and Akt. Am J Physiol Lung Cell Mol Physiol. 2020;318:L1036-L1055 pubmed publisher |
| Schimmel L, Fukuhara D, Richards M, Jin Y, Essebier P, Frampton E, et al. c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly. Development. 2020;147: pubmed publisher |
| van der Stoel M, Schimmel L, Nawaz K, van Stalborch A, de Haan A, Klaus Bergmann A, et al. DLC1 is a direct target of activated YAP/TAZ that drives collective migration and sprouting angiogenesis. J Cell Sci. 2020;133: pubmed publisher |
| Jaumouillé V, Cartagena Rivera A, Waterman C. Coupling of β2 integrins to actin by a mechanosensitive molecular clutch drives complement receptor-mediated phagocytosis. Nat Cell Biol. 2019;21:1357-1369 pubmed publisher |
| Dorland Y, Cornelissen A, Kuijk C, Tol S, Hoogenboezem M, van Buul J, et al. Nuclear shape, protrusive behaviour and in vivo retention of human bone marrow mesenchymal stromal cells is controlled by Lamin-A/C expression. Sci Rep. 2019;9:14401 pubmed publisher |
| Osborne N, Sundseth R, Gay M, Cao H, Tucker R, Nadella S, et al. Vaccine against gastrin, a polyclonal antibody stimulator, decreases pancreatic cancer metastases. Am J Physiol Gastrointest Liver Physiol. 2019;317:G682-G693 pubmed publisher |
| Pedrosa A, Bodrug N, Gómez Escudero J, Carter E, Reynolds L, Georgiou P, et al. Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and -861. Cancer Res. 2019;: pubmed publisher |
| Klomp J, Shaaya M, Matsche J, Rebiai R, Aaron J, Collins K, et al. Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response. Cell Chem Biol. 2019;: pubmed publisher |
| Rezey A, Gerlach B, Wang R, Liao G, Tang D. Plk1 Mediates Paxillin Phosphorylation (Ser-272), Centrosome Maturation, and Airway Smooth Muscle Layer Thickening in Allergic Asthma. Sci Rep. 2019;9:7555 pubmed publisher |
| Godoy Parejo C, Deng C, Liu W, Chen G. Insulin Stimulates PI3K/AKT and Cell Adhesion to Promote the Survival of Individualized Human Embryonic Stem Cells. Stem Cells. 2019;37:1030-1041 pubmed publisher |
| Tsygankova O, Keen J. A unique role for clathrin light chain A in cell spreading and migration. J Cell Sci. 2019;132: pubmed publisher |
| Jones M, Askari J, Humphries J, Humphries M. Cell adhesion is regulated by CDK1 during the cell cycle. J Cell Biol. 2018;217:3203-3218 pubmed publisher |
| Roycroft A, Szabo A, Bahm I, Daly L, Charras G, Parsons M, et al. Redistribution of Adhesive Forces through Src/FAK Drives Contact Inhibition of Locomotion in Neural Crest. Dev Cell. 2018;45:565-579.e3 pubmed publisher |
| Sun X, Hourwitz M, Baker E, Schmidt B, Losert W, Fourkas J. Replication of biocompatible, nanotopographic surfaces. Sci Rep. 2018;8:564 pubmed publisher |
| Stutchbury B, Atherton P, Tsang R, Wang D, Ballestrem C. Distinct focal adhesion protein modules control different aspects of mechanotransduction. J Cell Sci. 2017;130:1612-1624 pubmed publisher |
| Cieniewicz A, Kirchner T, Hinke S, Nanjunda R, D AQUINO K, Boayke K, et al. Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin Resistance. Diabetes. 2017;66:206-217 pubmed publisher |
| Tomas N, Hoxha E, Reinicke A, Fester L, Helmchen U, Gerth J, et al. Autoantibodies against thrombospondin type 1 domain-containing 7A induce membranous nephropathy. J Clin Invest. 2016;126:2519-32 pubmed publisher |
| Zimnicka A, Husain Y, Shajahan A, Sverdlov M, Chaga O, Chen Z, et al. Src-dependent phosphorylation of caveolin-1 Tyr-14 promotes swelling and release of caveolae. Mol Biol Cell. 2016;27:2090-106 pubmed publisher |
| Calvo F, Ranftl R, Hooper S, Farrugia A, Moeendarbary E, Bruckbauer A, et al. Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts. Cell Rep. 2015;13:2699-714 pubmed publisher |
| Wu J, Chen Y, Kuo C, Wenshin Yu H, Chen Y, Chiou A, et al. Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration. Sci Rep. 2015;5:18476 pubmed publisher |
| Horton E, Byron A, Askari J, Ng D, Millon Frémillon A, Robertson J, et al. Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly. Nat Cell Biol. 2015;17:1577-1587 pubmed publisher |
| Jiang J, Zhang Z, Yuan X, Poo M. Spatiotemporal dynamics of traction forces show three contraction centers in migratory neurons. J Cell Biol. 2015;209:759-74 pubmed publisher |
| Case L, Baird M, Shtengel G, Campbell S, Hess H, Davidson M, et al. Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions. Nat Cell Biol. 2015;17:880-92 pubmed publisher |
| Robertson J, Jacquemet G, Byron A, Jones M, Warwood S, Selley J, et al. Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling. Nat Commun. 2015;6:6265 pubmed publisher |
| Balcioglu H, van Hoorn H, Donato D, Schmidt T, Danen E. The integrin expression profile modulates orientation and dynamics of force transmission at cell-matrix adhesions. J Cell Sci. 2015;128:1316-26 pubmed publisher |
