JNK1 Polyclonal Antibody | Invitrogen 44-690G product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

JNK1 Polyclonal Antibody

catalog :

44-690G

quantity :

100 µL

price :

US 430.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig e6j	Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 2019;574:553-558 pubmed publisher
western blot; human; 1:200; loading ...; fig 4d	Ranjan K, Pathak C. Expression of FADD and cFLIPL balances mitochondrial integrity and redox signaling to substantiate apoptotic cell death. Mol Cell Biochem. 2016;422:135-150 pubmed
western blot; human; 1:200; fig 6g	Ranjan K, Pathak C. FADD regulates NF-ÎºB activation and promotes ubiquitination of cFLIPL to induce apoptosis. Sci Rep. 2016;6:22787 pubmed publisher
western blot; human; 1:1000; fig 3	Ranjan K, Pathak C. Expression of cFLIPL Determines the Basal Interaction of Bcl-2 With Beclin-1 and Regulates p53 Dependent Ubiquitination of Beclin-1 During Autophagic Stress. J Cell Biochem. 2016;117:1757-68 pubmed publisher
	Cao Y, Li H, Zhao J, Sun Y, Jin X, Lv S, et al. Mechanical Study of Jian-Gan-Xiao-Zhi Decoction on Nonalcoholic Fatty Liver Disease Based on Integrated Network Pharmacology and Untargeted Metabolomics. Evid Based Complement Alternat Med. 2022;2022:2264394 pubmed publisher
	Park D, Lalli J, Sedlackova Slavikova L, Rice S. Functional comparison of herpes simplex virus 1 (HSV-1) and HSV-2 ICP27 homologs reveals a role for ICP27 in virion release. J Virol. 2015;89:2892-905 pubmed publisher
	Bernusso V, Machado Neto J, Pericole F, Vieira K, Duarte A, Traina F, et al. Imatinib restores VASP activity and its interaction with Zyxin in BCR-ABL leukemic cells. Biochim Biophys Acta. 2015;1853:388-95 pubmed publisher

product information

Product Type :

Antibody

Product Name :

JNK1 Polyclonal Antibody

Catalog # :

44-690G

Quantity :

100 µL

Price :

US 430.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

MAPK8 (JNK1) is activated by the presence of misfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity. It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.

Immunogen :

The antiserum was produced against a chemically synthesized peptide derived from an internal region of JNK1. This region is conserved among human, mouse, and rat forms of JNK1, JNK2, and JNK3 proteins.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:1,000

Aliases :

AI849689; c-Jun N-terminal kinase 1; FLJ12099; FLJ33785; JNK; JNK1; JNK1 beta1 protein kinase; jnk1a-1; JNK1A2; JNK21B1/2; JNK3; JNK3A; JNK-46; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAPK 10; MAPK 8; MAPK10; Mapk8; mapk8 protein; mapk8b; MGC50974; mitogen activated protein kinase 8; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8b; MK10; OTTHUMP00000019552; p493F12; p54 gamma; p54bSAPK; Phospho-JNK; PRKM10; PRKM8; protein kinase JNK1; protein kinase mitogen-activated 8; SAPK gamma; SAPK1; SAPK1C; stress-activated protein kinase 1; stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; zgc:112379

more info or order :

Invitrogen product webpage