Phospho-PYK2 (Tyr402) Polyclonal Antibody, Alexa Fluor 488 | Invitrogen 44-618A1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-PYK2 (Tyr402) Polyclonal Antibody, Alexa Fluor 488

catalog :

44-618A1

quantity :

10 blots

price :

US 390

clonality :

polyclonal

host :

domestic rabbit

conjugate :

AF488

antigen modification :

phosphorylated

reactivity :

human, mouse, rat, chicken

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

Phospho-PYK2 (Tyr402) Polyclonal Antibody, Alexa Fluor 488

Catalog # :

44-618A1

Quantity :

10 blots

Price :

US 390

Clonality :

Polyclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Chicken, Human, Mouse, Rat

Applications :

Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Western Blot: 1:1000

Species :

Chicken, Human, Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Immunogen :

This antibody was produced against a chemically synthesized phosphopeptide derived from the region of Pyk2 that contains tyrosine 402. The antibody was affinity purified by sequential epitope-specific chromatography, then conjugated to Alexa Fluor® 488 under optimal conditions.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Western Blot: 1:1000

Aliases :

CADTK, CAKB, FADK2, PKB, PTK, PTK2B, RAFTK, Focal Adhesion Kinase 2