| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; loading ...; fig 7a
| Woodall B, Woodall M, Luongo T, Grisanti L, Tilley D, Elrod J, et al. Skeletal Muscle-specific G Protein-coupled Receptor Kinase 2 Ablation Alters Isolated Skeletal Muscle Mechanics and Enhances Clenbuterol-stimulated Hypertrophy. J Biol Chem. 2016;291:21913-21924 pubmed |
- western blot; mouse; loading ...; fig 1d
| Diez H, Benitez M, Fernandez S, Torres Aleman I, Garrido J, Wandosell F. Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation. Biochim Biophys Acta. 2016;1863:2574-2583 pubmed publisher |
- western blot; mouse; 1:1000; fig 4
| Manassero G, Guglielmotto M, Zamfir R, Borghi R, Colombo L, Salmona M, et al. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein. Aging Cell. 2016;15:914-23 pubmed publisher |
- western blot; mouse; 1:1000; fig 2
| Franco Villanueva A, Wandosell F, Antón I. Neuritic complexity of hippocampal neurons depends on WIP-mediated mTORC1 and Abl family kinases activities. Brain Behav. 2015;5:e00359 pubmed publisher |
- western blot; mouse; 1:3000; fig 2
| Cymerman I, Gozdz A, Urbanska M, Milek J, Dziembowska M, Jaworski J. Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3β. PLoS ONE. 2015;10:e0134018 pubmed publisher |
- western blot; mouse; 1:1000
| Monteiro da Rocha A, Ding J, Slawny N, Wolf A, Smith G. Loss of glycogen synthase kinase 3 isoforms during murine oocyte growth induces offspring cardiac dysfunction. Biol Reprod. 2015;92:127 pubmed publisher |
- western blot; mouse; 1:5000; fig 1
| Ko R, Park J, Ha H, Choi Y, Lee S. Glycogen synthase kinase 3β ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production. Nat Commun. 2015;6:6765 pubmed publisher |
- western blot; human; fig 4a
- western blot; rat; fig 4d
| Cuesto G, Jordán Álvarez S, Enriquez Barreto L, Ferrús A, Morales M, Acebes A. GSK3β inhibition promotes synaptogenesis in Drosophila and mammalian neurons. PLoS ONE. 2015;10:e0118475 pubmed publisher |
- western blot; human; fig s1
| Banach Orlowska M, Szymańska E, Miaczynska M. APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription. FEBS Lett. 2015;589:532-9 pubmed publisher |
- western blot; mouse; 1:1000
| Bhattacharjee R, Goswami S, Dudiki T, Popkie A, Phiel C, Kline D, et al. Targeted disruption of glycogen synthase kinase 3A (GSK3A) in mice affects sperm motility resulting in male infertility. Biol Reprod. 2015;92:65 pubmed publisher |
- western blot; rat; 1:1000
| Pérez Alvarez M, Mateos L, Alonso A, Wandosell F. Estradiol and Progesterone Administration After pMCAO Stimulates the Neurological Recovery and Reduces the Detrimental Effect of Ischemia Mainly in Hippocampus. Mol Neurobiol. 2015;52:1690-1703 pubmed publisher |
| Maurin H, Lechat B, Borghgraef P, Devijver H, Jaworski T, Van Leuven F. Terminal hypothermic Tau.P301L mice have increased Tau phosphorylation independently of glycogen synthase kinase 3?/?. Eur J Neurosci. 2014;40:2442-53 pubmed publisher |
- western blot; mouse; 1:4000; fig 3, 5
| Wadosky K, Rodriguez J, Hite R, Min J, Walton B, Willis M. Muscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling. Am J Physiol Endocrinol Metab. 2014;306:E723-39 pubmed publisher |
- western blot; mouse; 1:1000
| Griffeth R, Carretero J, Burks D. Insulin receptor substrate 2 is required for testicular development. PLoS ONE. 2013;8:e62103 pubmed publisher |
- western blot; mouse; fig 2
| Maurin H, Lechat B, Dewachter I, Ris L, Louis J, Borghgraef P, et al. Neurological characterization of mice deficient in GSK3? highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase. Mol Brain. 2013;6:27 pubmed publisher |
- western blot; mouse; 1:2000
| Willis M, Min J, Wang S, McDonough H, Lockyer P, Wadosky K, et al. Carboxyl terminus of Hsp70-interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise. Cell Biochem Funct. 2013;31:724-35 pubmed publisher |
- western blot; human; fig 5
| Zhou X, Wang H, Burg M, Ferraris J. Inhibitory phosphorylation of GSK-3? by AKT, PKA, and PI3K contributes to high NaCl-induced activation of the transcription factor NFAT5 (TonEBP/OREBP). Am J Physiol Renal Physiol. 2013;304:F908-17 pubmed publisher |
| Wang H, Ducommun S, Quan C, Xie B, Li M, Wasserman D, et al. AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues. Biochem J. 2013;449:479-89 pubmed publisher |
- western blot; rat; 1:1000; fig 5
| Pérez Alvarez M, Maza M, Anton M, Ordoñez L, Wandosell F. Post-ischemic estradiol treatment reduced glial response and triggers distinct cortical and hippocampal signaling in a rat model of cerebral ischemia. J Neuroinflammation. 2012;9:157 pubmed publisher |
- western blot; mouse; 1:1000; fig s2
| Wray J, Kalkan T, Gómez López S, Eckardt D, Cook A, Kemler R, et al. Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nat Cell Biol. 2011;13:838-45 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Goñi Oliver P, Avila J, Hernandez F. Calpain regulates N-terminal interaction of GSK-3? with 14-3-3?, p53 and PKB but not with axin. Neurochem Int. 2011;59:97-100 pubmed publisher |
- western blot; mouse; fig 1
| García Martínez J, Wullschleger S, Preston G, Guichard S, Fleming S, Alessi D, et al. Effect of PI3K- and mTOR-specific inhibitors on spontaneous B-cell follicular lymphomas in PTEN/LKB1-deficient mice. Br J Cancer. 2011;104:1116-25 pubmed publisher |
- western blot; human; fig 3
| García Martínez J, Moran J, Clarke R, Gray A, Cosulich S, Chresta C, et al. Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR). Biochem J. 2009;421:29-42 pubmed publisher |
| Cole A, Sutherland C. Measuring GSK3 expression and activity in cells. Methods Mol Biol. 2008;468:45-65 pubmed publisher |
- western blot; rat; 1:6000; fig 6
| Sun H, Xu B, Sheveleva E, Chen Q. LY294002 inhibits glucocorticoid-induced COX-2 gene expression in cardiomyocytes through a phosphatidylinositol 3 kinase-independent mechanism. Toxicol Appl Pharmacol. 2008;232:25-32 pubmed publisher |
- western blot; mouse; fig 1
| Bouskila M, Hirshman M, Jensen J, Goodyear L, Sakamoto K. Insulin promotes glycogen synthesis in the absence of GSK3 phosphorylation in skeletal muscle. Am J Physiol Endocrinol Metab. 2008;294:E28-35 pubmed |
- western blot; mouse; fig 3
| Mora A, Sakamoto K, McManus E, Alessi D. Role of the PDK1-PKB-GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart. FEBS Lett. 2005;579:3632-8 pubmed |
| Cao Y, Li H, Zhao J, Sun Y, Jin X, Lv S, et al. Mechanical Study of Jian-Gan-Xiao-Zhi Decoction on Nonalcoholic Fatty Liver Disease Based on Integrated Network Pharmacology and Untargeted Metabolomics. Evid Based Complement Alternat Med. 2022;2022:2264394 pubmed publisher |
| Kisseleff E, Vigouroux R, Hottin C, Lourdel S, Thomas L, Shah P, et al. Glycogen Synthase Kinase 3 Regulates the Genesis of Displaced Retinal Ganglion Cells3. Eneuro. 2021;8: pubmed publisher |
| Kopietz F, Alshuweishi Y, Bijland S, Alghamdi F, Degerman E, Sakamoto K, et al. A-769662 inhibits adipocyte glucose uptake in an AMPK-independent manner. Biochem J. 2021;478:633-646 pubmed publisher |
| Draffin J, Sánchez Castillo C, Fernández Rodrigo A, Sánchez Sáez X, Avila J, Wagner F, et al. GSK3α, not GSK3β, drives hippocampal NMDAR-dependent LTD via tau-mediated spine anchoring. EMBO J. 2021;40:e105513 pubmed publisher |
| Guglielmotto M, Manassero G, Vasciaveo V, Venezia M, Tabaton M, Tamagno E. Estrogens Inhibit Amyloid-β-Mediated Paired Helical Filament-Like Conformation of Tau Through Antioxidant Activity and miRNA 218 Regulation in hTau Mice. J Alzheimers Dis. 2020;77:1339-1351 pubmed publisher |
| Kopietz F, Rupar K, Berggreen C, S xe4 ll J, Vertommen D, Degerman E, et al. Inhibition of AMPK activity in response to insulin in adipocytes: involvement of AMPK pS485, PDEs, and cellular energy levels. Am J Physiol Endocrinol Metab. 2020;319:E459-E471 pubmed publisher |
| Herrera J, Ordóñez Gutiérrez L, Fabrias G, Casas J, Morales A, Hernández G, et al. Ovarian Hormone-Dependent Effects of Dietary Lipids on APP/PS1 Mouse Brain. Front Aging Neurosci. 2019;11:346 pubmed publisher |
| Dey S, Eisa A, Kline D, Wagner F, Abeysirigunawardena S, Vijayaraghavan S. Roles of glycogen synthase kinase 3 alpha and calcineurin in regulating the ability of sperm to fertilize eggs. FASEB J. 2020;34:1247-1269 pubmed publisher |
| Zhong W, Darmani N. The pivotal role of glycogen synthase kinase 3 (GSK-3) in vomiting evoked by specific emetogens in the least shrew (Cryptotis parva). Neurochem Int. 2020;132:104603 pubmed publisher |
| Martín Segura A, Ahmed T, Casadomé Perales Á, Palomares Perez I, Palomer E, Kerstens A, et al. Age-associated cholesterol reduction triggers brain insulin resistance by facilitating ligand-independent receptor activation and pathway desensitization. Aging Cell. 2019;18:e12932 pubmed publisher |
| Freitas M, Silva J, Brothag C, Regadas Correia B, Fardilha M, Vijayaraghavan S. Isoform-specific GSK3A activity is negatively correlated with human sperm motility. Mol Hum Reprod. 2019;25:171-183 pubmed publisher |
| Urbanska M, Kazmierska Grebowska P, Kowalczyk T, Caban B, Nader K, Pijet B, et al. GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation. EBioMedicine. 2019;39:377-387 pubmed publisher |
| Gozdz A, Nikolaienko O, Urbanska M, Cymerman I, Sitkiewicz E, Blazejczyk M, et al. GSK3? and GSK3? Phosphorylate Arc and Regulate its Degradation. Front Mol Neurosci. 2017;10:192 pubmed publisher |
| Irimia J, Meyer C, Segvich D, Surendran S, DePaoli Roach A, Morral N, et al. Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice. J Biol Chem. 2017;292:10455-10464 pubmed publisher |
| Wullschleger S, Wasserman D, Gray A, Sakamoto K, Alessi D. Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis. Biochem J. 2011;434:265-74 pubmed publisher |
| Pearce L, Alton G, Richter D, Kath J, Lingardo L, Chapman J, et al. Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). Biochem J. 2010;431:245-55 pubmed publisher |
| Asenjo A, González Armas J, Villanueva N. Phosphorylation of human respiratory syncytial virus P protein at serine 54 regulates viral uncoating. Virology. 2008;380:26-33 pubmed publisher |
| Kelleher I, Garwood C, Hanger D, Anderton B, Noble W. Kinase activities increase during the development of tauopathy in htau mice. J Neurochem. 2007;103:2256-67 pubmed |
| Taurin S, Sandbo N, Qin Y, Browning D, Dulin N. Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase. J Biol Chem. 2006;281:9971-6 pubmed |
| Medunjanin S, Hermani A, De Servi B, Grisouard J, Rincke G, Mayer D. Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity. J Biol Chem. 2005;280:33006-14 pubmed |
| McManus E, Sakamoto K, Armit L, Ronaldson L, Shpiro N, Marquez R, et al. Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis. EMBO J. 2005;24:1571-83 pubmed |
