Phospho-VAV1 (Tyr160) Polyclonal Antibody | Invitrogen 44-482 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-VAV1 (Tyr160) Polyclonal Antibody

catalog :

44-482

quantity :

100 µL

price :

US 430

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse

application :

western blot, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 1 western blot; human; fig 2	Vivar O, Masi G, Carpier J, Magalhaes J, Galgano D, Pazour G, et al. IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Proc Natl Acad Sci U S A. 2016;113:386-91 pubmed publisher
	Dhar P, Basher F, Ji Z, Huang L, Qin S, Wainwright D, et al. Tumor-derived NKG2D ligand sMIC reprograms NK cells to an inflammatory phenotype through CBM signalosome activation. Commun Biol. 2021;4:905 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-VAV1 (Tyr160) Polyclonal Antibody

Catalog # :

44-482

Quantity :

100 µL

Price :

US 430

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000

Species :

Human

Isotype :

IgG

Storage :

-20°C

Description :

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Immunogen :

A chemically synthesized phosphopeptide derived from a region of human Vav1 that contains tyrosine 160

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000

Aliases :

oncogene vav; p95; p95vav; Proto-oncogene vav; VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav guanine nucleotide exchange factor 1; vav oncogene; vav proto-oncogene; VAV1; vav-T

more info or order :

Invitrogen product webpage