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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
STAT2 Polyclonal Antibody
catalog :
44-362G
quantity :
100 µL
price :
US 514
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig s11c
Hsiue E, Wright K, Douglass J, Hwang M, Mog B, Pearlman A, et al. Targeting a neoantigen derived from a common TP53 mutation. Science. 2021;371: pubmed publisher
Dhayal S, Leslie K, Baity M, Akhbari P, Richardson S, Russell M, et al. Temporal regulation of interferon signalling in human EndoC-βH1 cells. J Mol Endocrinol. 2022;69:299-313 pubmed publisher
Conde J, Schutt W, Mladinich M, Sohn S, Hearing P, Mackow E. NS5 Sumoylation Directs Nuclear Responses That Permit Zika Virus To Persistently Infect Human Brain Microvascular Endothelial Cells. J Virol. 2020;94: pubmed publisher
product information
Product Type :
Antibody
Product Name :
STAT2 Polyclonal Antibody
Catalog # :
44-362G
Quantity :
100 µL
Price :
US 514
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
ChIP Assay: 10 µL, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: 1:200-1:2,000, Western Blot: 1:1,000
Species :
Human
Isotype :
IgG
Storage :
-20°C
Description :
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
Immunogen :
The antiserum was produced against a chemically synthesized peptide derived from the C-terminal region of human STAT2.
Format :
Liquid
Applications w/Dilutions :
ChIP Assay: 10 µL, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: 1:200-1:2,000, Western Blot: 1:1,000
Aliases :
1110034C02Rik; 1600010G07Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; Aprf; AW109958; AW496480; DNA-binding protein APRF; EGK_03803; HIES; IMD44; interferon alpha induced transcriptional activator; ISGF-3; MGC59816; p113; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kDa; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); STAT; STAT 2; STAT113; STAT2; STAT-2; Stat3
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA