beta Amyloid (1-42) Polyclonal Antibody | Invitrogen 44-344 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

beta Amyloid (1-42) Polyclonal Antibody

catalog :

44-344

quantity :

25 µg

price :

US 446.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

African green monkey, human, mouse

application :

ELISA, immunohistochemistry, immunohistochemistry - frozen section, dot blot, other

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:2500; loading ...; fig 4a	Mellott T, Huleatt O, Shade B, Pender S, Liu Y, Slack B, et al. Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. PLoS ONE. 2017;12:e0170450 pubmed publisher
immunohistochemistry - frozen section; African green monkey; 1:200; loading ...; fig 1f	Rodriguez Callejas J, Fuchs E, Perez Cruz C. Evidence of Tau Hyperphosphorylation and Dystrophic Microglia in the Common Marmoset. Front Aging Neurosci. 2016;8:315 pubmed publisher
other; human; 1:300; fig 2	Kim C, Lim E, Shin S, Krause H, Hong H. Magnetic immunoassay platform based on the planar frequency mixing magnetic technique. Biosens Bioelectron. 2016;83:293-9 pubmed publisher
	Pilozzi A, Yu Z, Carreras I, Cormier K, Hartley D, Rogers J, et al. A Preliminary Study of Cu Exposure Effects upon Alzheimer's Amyloid Pathology. Biomolecules. 2020;10: pubmed publisher
	Kechko O, Petrushanko I, Brower C, Adzhubei A, Moskalev A, Piatkov K, et al. Beta-amyloid induces apoptosis of neuronal cells by inhibition of the Arg/N-end rule pathway proteolytic activity. Aging (Albany NY). 2019;11:6134-6152 pubmed publisher
	Kawarabayashi T, Terakawa T, Takahashi A, Hasegawa H, Narita S, Sato K, et al. Oral Immunization with Soybean Storage Protein Containing Amyloid-β 4-10 Prevents Spatial Learning Decline. J Alzheimers Dis. 2019;70:487-503 pubmed publisher
	Dolfe L, Tambaro S, Tigro H, Del Campo M, Hoozemans J, Wiehager B, et al. The Bri2 and Bri3 BRICHOS Domains Interact Differently with Aβ42 and Alzheimer Amyloid Plaques. J Alzheimers Dis Rep. 2018;2:27-39 pubmed publisher
	Aytan N, Choi J, Carreras I, Crabtree L, Nguyen B, Lehar M, et al. Protective effects of 7,8-dihydroxyflavone on neuropathological and neurochemical changes in a mouse model of Alzheimer's disease. Eur J Pharmacol. 2018;828:9-17 pubmed publisher
	Zhang J, Chen C. Alleviation of Neuropathology by Inhibition of Monoacylglycerol Lipase in APP Transgenic Mice Lacking CB2 Receptors. Mol Neurobiol. 2018;55:4802-4810 pubmed publisher
	Niwa A, Ii Y, Shindo A, Matsuo K, Ishikawa H, Taniguchi A, et al. Comparative Analysis of Cortical Microinfarcts and Microbleeds using 3.0-Tesla Postmortem Magnetic Resonance Images and Histopathology. J Alzheimers Dis. 2017;59:951-959 pubmed publisher
	Ostapchenko V, Chen M, Guzman M, Xie Y, Lavine N, Fan J, et al. The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to Î²-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment. J Neurosci. 2015;35:15157-69 pubmed publisher
	Webster S, Van Eldik L, Watterson D, Bachstetter A. Closed head injury in an age-related Alzheimer mouse model leads to an altered neuroinflammatory response and persistent cognitive impairment. J Neurosci. 2015;35:6554-69 pubmed publisher

product information

Product Type :

Antibody

Product Name :

beta Amyloid (1-42) Polyclonal Antibody

Catalog # :

44-344

Quantity :

25 µg

Price :

US 446.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Dot Blot: Assay-dependent, ELISA: 1 µg/mL, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Radioimmune assays: Assay-dependent

Species :

Human

Isotype :

IgG

Storage :

-20°C

Description :

Beta amyloid is a 40–43 amino acid peptide cleaved from amyloid precursor protein by a protease, gamma-secretase. Beta Amyloid (1-40) (Amyloid beta 40 or Abeta 40) together with beta Amyloid (1-42) (Amyloid beta 42 or Abeta 42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the Amyloid beta 40 and Amyloid beta 42 alloforms are major components of the extracellular plaques found in Alzheimer's disease brain tissue.

Immunogen :

Synthetic peptide derived from amino acids 36-42 within the C-terminal region of human beta-Amyloid protein

Format :

Liquid

Applications w/Dilutions :

Dot Blot: Assay-dependent, ELISA: 1 µg/mL, Functional Assay: Assay-dependent, Immunohistochemistry: Assay-dependent, Radioimmune assays: Assay-dependent

Aliases :

A beta 1 42; A ß 1 42; A4; AAA; AB42; Abeta; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; Amyloid beta 1 42; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid ß; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; Aß 1 42; B APP42; BAPP42; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; Beta-APP40; BetaAPP42; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; Cvap; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; P3(40); P3(42); peptidase nexin-II; PN2; PN-II; PreA4; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2; ß APP42; ßAPP42

more info or order :

Invitrogen product webpage