This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
OPRK1 Polyclonal Antibody
catalog :
44-302G
quantity :
100 uL
price :
US 471.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, immunocytochemistry
citations: 6
Reference
Terminel M, Bassil C, Rau J, Trevino A, Ruiz C, Alaniz R, et al. Morphine-induced changes in the function of microglia and macrophages after acute spinal cord injury. BMC Neurosci. 2022;23:58 pubmed publisher
Watanabe M, Kopruszinski C, Moutal A, Ikegami D, Khanna R, Chen Y, et al. Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine. Brain. 2022;145:2894-2909 pubmed publisher
Lorente J, Cuitavi J, Campos Jurado Y, Mont xf3 n Molina R, Gonz xe1 lez Romero J, Hip xf3 lito L. Kappa opioid receptor blockade in the nucleus accumbens shell prevents sex-dependent alcohol deprivation effect induced by inflammatory pain. Pain. 2022;163:e137-e147 pubmed publisher
Martin L, Moutal A, Cheng K, Washington S, Calligaro H, Goel V, et al. Green Light Antinociceptive and Reversal of Thermal and Mechanical Hypersensitivity Effects Rely on Endogenous Opioid System Stimulation. J Pain. 2021;22:1646-1656 pubmed publisher
Hestehave S, Abelson K, Brønnum Pedersen T, Finn D, Andersson D, Munro G. The influence of rat strain on the development of neuropathic pain and comorbid anxio-depressive behaviour after nerve injury. Sci Rep. 2020;10:20981 pubmed publisher
Zádor F, Lénárt N, Csibrány B, Sántha M, Molnár M, Tuka B, et al. Low dosage of rimonabant leads to anxiolytic-like behavior via inhibiting expression levels and G-protein activity of kappa opioid receptors in a cannabinoid receptor independent manner. Neuropharmacology. 2015;89:298-307 pubmed
product information
Product Type :
Antibody
Product Name :
OPRK1 Polyclonal Antibody
Catalog # :
44-302G
Quantity :
100 uL
Price :
US 471.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Mouse, Rat
Applications :
Immunocytochemistry: 1:250, Western Blot: 1:1,000
Species :
Mouse, Rat
Isotype :
IgG
Storage :
-20 C
Description :
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Immunogen :
The antiserum was produced against a chemically synthesized peptide derived from the internal region of the mouse k-opioid receptor. The sequence is conserved in rat.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:250, Western Blot: 1:1,000
Aliases :
kappa opioid receptor; kappa-type opioid receptor; KOPR1; KOR; K-OR-1; KOR-1; MSL-1; Opiate receptor, kappa-1; opioid receptor kappa 1; opioid receptor, kappa 1; opioid receptor, kappa 2; OPRK; OPRK1; Oprk2; Ork1; R21; Ror-d
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA