beta Amyloid (1-40) Polyclonal Antibody | Invitrogen 44-136 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

beta Amyloid (1-40) Polyclonal Antibody

catalog :

44-136

quantity :

100 µg

price :

US 500.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

African green monkey, human

application :

ELISA, immunohistochemistry, immunohistochemistry - frozen section, dot blot

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; African green monkey; 1:200; loading ...; fig 1h	Rodriguez Callejas J, Fuchs E, Perez Cruz C. Evidence of Tau Hyperphosphorylation and Dystrophic Microglia in the Common Marmoset. Front Aging Neurosci. 2016;8:315 pubmed publisher
immunohistochemistry; human; 1:1000; loading ...; fig 4d	Bangasser D, Dong H, Carroll J, Plona Z, Ding H, Rodriguez L, et al. Corticotropin-releasing factor overexpression gives rise to sex differences in Alzheimer's disease-related signaling. Mol Psychiatry. 2017;22:1126-1133 pubmed publisher
	Rofo F, Metzendorf N, Saubi C, Suominen L, Godec A, Sehlin D, et al. Blood-brain barrier penetrating neprilysin degrades monomeric amyloid-beta in a mouse model of Alzheimer's disease. Alzheimers Res Ther. 2022;14:180 pubmed publisher
	Khorani M, Bobe G, Matthews D, Magaña A, Caruso M, Gray N, et al. The Impact of the hAPP695SW Transgene and Associated Amyloid-β Accumulation on Murine Hippocampal Biochemical Pathways. J Alzheimers Dis. 2022;85:1601-1619 pubmed publisher
	Rofo F, Ugur Yilmaz C, Metzendorf N, Gustavsson T, Beretta C, Erlandsson A, et al. Enhanced neprilysin-mediated degradation of hippocampal Aβ42 with a somatostatin peptide that enters the brain. Theranostics. 2021;11:789-804 pubmed publisher
	Yakushiji Y, Kawamoto K, Uchihashi K, Ihara M, Aoki S, Nagaishi Y, et al. Low-Dose Phosphodiesterase III Inhibitor Reduces the Vascular Amyloid Burden in Amyloid-β Protein Precursor Transgenic Mice. Int J Mol Sci. 2020;21: pubmed publisher
	Matthews D, Caruso M, Murchison C, Zhu J, Wright K, Harris C, et al. Centella Asiatica Improves Memory and Promotes Antioxidative Signaling in 5XFAD Mice. Antioxidants (Basel). 2019;8: pubmed publisher
	Poncelet L, Ando K, Vergara C, Mansour S, Suain V, Yilmaz Z, et al. A 4R tauopathy develops without amyloid deposits in aged cat brains. Neurobiol Aging. 2019;81:200-212 pubmed publisher
	Medawar E, Benway T, Liu W, Hanan T, Haslehurst P, James O, et al. Effects of rising amyloidβ levels on hippocampal synaptic transmission, microglial response and cognition in APPSwe/PSEN1M146V transgenic mice. EBioMedicine. 2019;39:422-435 pubmed publisher

product information

Product Type :

Antibody

Product Name :

beta Amyloid (1-40) Polyclonal Antibody

Catalog # :

44-136

Quantity :

100 µg

Price :

US 500.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Dot Blot: Assay-dependent, ELISA: 1 µg/mL, Immunohistochemistry: Assay-dependent, Radioimmune assays: Assay-dependent

Species :

Human

Isotype :

IgG

Storage :

-20°C

Description :

Beta-amyloid is a 40–43 amino acid peptide cleaved from amyloid precursor protein, and a putative gamma-secretase. Amyloid beta (1-40) together with Amyloid beta (1-42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the amyloid beta (40) and amyloid beta (42) alloforms are major components of the extracellular plaques found in Alzheimer's disease brain tissue.

Immunogen :

The antiserum was produced against a chemically synthesized peptide corresponding to amino acids 1-40 of human beta-Amyloid (A-beta).

Format :

Liquid

Applications w/Dilutions :

Dot Blot: Assay-dependent, ELISA: 1 µg/mL, Immunohistochemistry: Assay-dependent, Radioimmune assays: Assay-dependent

Aliases :

A beta 1 40; A ß 1 40; A4; AAA; AB40; Abeta; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; Amyloid beta 1 40; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid ß; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; App; APP-C57; APP-C59; APP-C99; APPI; appican; Aß 1 40; B APP40; BAPP40; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; BetaAPP40; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; P3(40); P3(42); peptidase nexin-II; PN2; PN-II; PreA4; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; ß APP40; ßAPP40; testicular tissue protein Li 2

more info or order :

Invitrogen product webpage