Phospho-SGK1 (Thr256) Polyclonal Antibody | Invitrogen 44-1260G product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-SGK1 (Thr256) Polyclonal Antibody

catalog :

44-1260G

quantity :

100 uL

price :

US 520.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 6

Reference
Tang L, Yang X, Yu S, Qin Q, Xue R, Sun Y, et al. Aldosterone-stimulated endothelial epithelial sodium channel (EnNaC) plays a role in cold exposure-induced hypertension in rats. Front Pharmacol. 2022;13:970812 pubmed publisher
Ahsan M, Dos Reis D, Barbieri A, Sumigray K, Nottoli T, SALAS P, et al. Loss of Serum Glucocorticoid-Inducible Kinase 1 SGK1 Worsens Malabsorption and Diarrhea in Microvillus Inclusion Disease (MVID). J Clin Med. 2022;11: pubmed publisher
Li R, Wang X, Huang Z, Balaji J, Kim T, Wang T, et al. The role of epithelial progesterone receptor isoforms in embryo implantation. iScience. 2021;24:103487 pubmed publisher
Ugwu N, Atzmony L, Ellis K, Panse G, Jain D, Ko C, et al. Cutaneous and hepatic vascular lesions due to a recurrent somatic GJA4 mutation reveal a pathway for vascular malformation. HGG Adv. 2021;2: pubmed publisher
Yang X, Niu N, Liang C, Wu M, Tang L, Wang Q, et al. Stimulation of Epithelial Sodium Channels in Endothelial Cells by Bone Morphogenetic Protein-4 Contributes to Salt-Sensitive Hypertension in Rats. Oxid Med Cell Longev. 2020;2020:3921897 pubmed publisher
Ahsan M, Figueroa Hall L, Baratta V, Garcia Milian R, Lam T, Hoque K, et al. Glucocorticoids and serum- and glucocorticoid-inducible kinase 1 are potent regulators of CFTR in the native intestine: implications for stress-induced diarrhea. Am J Physiol Gastrointest Liver Physiol. 2020;319:G121-G132 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-SGK1 (Thr256) Polyclonal Antibody

Catalog # :

44-1260G

Quantity :

100 uL

Price :

US 520.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.

Immunogen :

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human SGK1 that contains threonine 256.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1,000

Aliases :

serine/threonine protein kinase SGK; serine/threonine-protein kinase Sgk1; serum and glucocorticoid-dependent protein kinase; serum/glucocorticoid regulated kinase 1; serum/glucocorticoid-regulated kinase 1; Sgk; SGK1; Sgk1 variant i3