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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Phospho-AS160 (Thr642) Polyclonal Antibody
catalog :
44-1071G
quantity :
100 µL
price :
US 425.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse
application :
western blot
more info or order :
Invitrogen product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 2f
Zhang W, Wu M, Kim T, Jariwala R, Garvey W, Luo N, et al. Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet-Induced Insulin Resistance. Diabetes. 2016;65:2380-91 pubmed publisher
Meng Z, Gong J, Chen Z, Sun J, Xiao Y, Wang L, et al. Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis. Mol Cell. 2017;66:332-344.e4 pubmed publisher
Quan C, Xie B, Wang H, Chen S. PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart. PLoS ONE. 2015;10:e0124491 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Phospho-AS160 (Thr642) Polyclonal Antibody
Catalog # :
44-1071G
Quantity :
100 µL
Price :
US 425.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Western Blot: 1:1,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20°C
Description :
AS160 (TBC1D4) is a GTPase-activiting protein for RAB2A, RAB8A, RAB10, and RAB14. The isoform 2 version of this protein promotes the insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane. This movement increases glucose uptake. Mutations associated with the gene cause Diabetes mellitus, non-insulin-dependent, 5 (NIDDM5).
Immunogen :
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human AS160 that contains threonine 642. The sequence is conserved in mouse.
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:1,000
Aliases :
5930406J04Rik; A930035N22; Akt substrate of 160 kDa; AS160; AV295684; DKFZp779C0666; Kiaa0603; NIDDM5; OTTHUMP00000040818; RGD1561609; RP11-159J2.1; RP11-159J2.3; similar to TBC1 domain family member 4; TBC (Tre-2, BUB2, CDC16) domain-containing protein; TBC Tre-2; TBC1 domain family member 4; TBC1 domain family, member 4; TBC1D4
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA